KEGG   Sus scrofa (pig): 396610Help
Entry
396610            CDS       T01009                                 

Gene name
MAPK8, JNK, JNK1
Definition
mitogen-activated protein kinase 8
Orthology
K04440  
c-Jun N-terminal kinase [EC:2.7.11.24]
Organism
ssc  Sus scrofa (pig)
Pathway
MAPK signaling pathway
ErbB signaling pathway
Ras signaling pathway
cAMP signaling pathway
FoxO signaling pathway
Protein processing in endoplasmic reticulum
Wnt signaling pathway
Osteoclast differentiation
Focal adhesion
Toll-like receptor signaling pathway
NOD-like receptor signaling pathway
RIG-I-like receptor signaling pathway
Fc epsilon RI signaling pathway
TNF signaling pathway
Neurotrophin signaling pathway
Retrograde endocannabinoid signaling
Dopaminergic synapse
Inflammatory mediator regulation of TRP channels
Insulin signaling pathway
GnRH signaling pathway
Progesterone-mediated oocyte maturation
Prolactin signaling pathway
Adipocytokine signaling pathway
Type II diabetes mellitus
Non-alcoholic fatty liver disease (NAFLD)
Salmonella infection
Pertussis
Chagas disease (American trypanosomiasis)
Toxoplasmosis
Tuberculosis
Hepatitis C
Hepatitis B
Influenza A
Herpes simplex infection
Epstein-Barr virus infection
Pathways in cancer
Colorectal cancer
Pancreatic cancer
Brite
KEGG Orthology (KO) [BR:ssc00001]
 Genetic Information Processing
  Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    396610 (MAPK8)
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    396610 (MAPK8)
   04010 MAPK signaling pathway
    396610 (MAPK8)
   04012 ErbB signaling pathway
    396610 (MAPK8)
   04310 Wnt signaling pathway
    396610 (MAPK8)
   04668 TNF signaling pathway
    396610 (MAPK8)
   04068 FoxO signaling pathway
    396610 (MAPK8)
   04024 cAMP signaling pathway
    396610 (MAPK8)
 Cellular Processes
  Cellular commiunity
   04510 Focal adhesion
    396610 (MAPK8)
 Organismal Systems
  Immune system
   04620 Toll-like receptor signaling pathway
    396610 (MAPK8)
   04621 NOD-like receptor signaling pathway
    396610 (MAPK8)
   04622 RIG-I-like receptor signaling pathway
    396610 (MAPK8)
   04664 Fc epsilon RI signaling pathway
    396610 (MAPK8)
  Endocrine system
   04910 Insulin signaling pathway
    396610 (MAPK8)
   04920 Adipocytokine signaling pathway
    396610 (MAPK8)
   04912 GnRH signaling pathway
    396610 (MAPK8)
   04914 Progesterone-mediated oocyte maturation
    396610 (MAPK8)
   04917 Prolactin signaling pathway
    396610 (MAPK8)
  Nervous system
   04728 Dopaminergic synapse
    396610 (MAPK8)
   04723 Retrograde endocannabinoid signaling
    396610 (MAPK8)
   04722 Neurotrophin signaling pathway
    396610 (MAPK8)
  Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    396610 (MAPK8)
  Development
   04380 Osteoclast differentiation
    396610 (MAPK8)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    396610 (MAPK8)
   05210 Colorectal cancer
    396610 (MAPK8)
   05212 Pancreatic cancer
    396610 (MAPK8)
  Endocrine and metabolic diseases
   04930 Type II diabetes mellitus
    396610 (MAPK8)
   04932 Non-alcoholic fatty liver disease (NAFLD)
    396610 (MAPK8)
  Infectious diseases
   05132 Salmonella infection
    396610 (MAPK8)
   05133 Pertussis
    396610 (MAPK8)
   05152 Tuberculosis
    396610 (MAPK8)
   05164 Influenza A
    396610 (MAPK8)
   05161 Hepatitis B
    396610 (MAPK8)
   05160 Hepatitis C
    396610 (MAPK8)
   05168 Herpes simplex infection
    396610 (MAPK8)
   05169 Epstein-Barr virus infection
    396610 (MAPK8)
   05145 Toxoplasmosis
    396610 (MAPK8)
   05142 Chagas disease (American trypanosomiasis)
    396610 (MAPK8)
Enzymes [BR:ssc01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     396610 (MAPK8)
Protein kinases [BR:ssc01001]
 Serine/threonine protein kinases: CMGC group
  MAPK family [OT]
   396610 (MAPK8)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Ensembl: 
UniProt: 
Position
14
AA seq 427 aa AA seqDB search
MSRSKRDSNFYSVEIGDSTFTVLKRYQNLKPIGSGAQGIVCAAFDAILERNVAIKKLSRP
FQNQTHAKRAYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQ
MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSF
MMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGEMIKGGVLFPGTDHIDQWNKVIEQ
LGTPCPEFMKKLQPTVRTYVENRPKYAGYSFEKLFPDVLFPADSEHNKLKASQARDLLSK
MLVIDASKRISVDEALQHPYINVWYDPSEAEAPPPKIPDKQLDEREHTIEEWKELIYKEV
MDLEERTKNGVIRGQPSPLGAAVINGSQHPSSSSSVNDVSSMSTDPTLASDTDSSLEASA
GPLGCCR
NT seq 1284 nt NT seq  +upstreamnt  +downstreamnt
atgagcagaagcaagcgtgacagcaatttttatagtgtagagattggagattctacattc
actgtcctgaaacggtatcagaatttaaaaccaataggctcaggagctcaaggaatagta
tgtgcagcttttgatgccattcttgaaagaaatgttgcaatcaagaagttaagccggcca
tttcagaatcagactcatgctaagcgtgcttacagagagctagttcttatgaaatgtgta
aatcacaaaaatataattggccttttgaatgttttcacaccacagaaatccctagaagaa
tttcaagatgtttacatagttatggagctcatggatgcaaatctttgtcaagtgattcag
atggaactagatcatgaaagaatgtcttaccttctctatcagatgctttgtggaatcaag
caccttcactctgctggaattattcatcgggacttaaagcccagtaatatagtggtaaaa
tcagactgcactttgaagattcttgactttggactggccaggactgcaggaactagtttt
atgatgacaccttacgtagtgactcgctactacagagcacctgaggtcatcctagggatg
ggctacaaagaaaacgttgacatttggtcagttgggtgcatcatgggagaaatgatcaaa
ggtggtgttttgttcccaggtacagatcatattgatcaatggaataaagttattgaacag
cttggaacaccatgtcccgaattcatgaagaaactacaaccaacagtaaggacttacgtc
gaaaacagacctaaatatgctggatatagctttgagaagctctttcctgatgtacttttc
ccagccgattcggagcacaacaaacttaaagctagtcaggcaagggatttgttatccaaa
atgctggtaattgatgcatctaaaaggatctctgtagatgaagctctccagcacccttac
attaatgtctggtatgatccttctgaagctgaagctccaccaccaaagatacctgacaag
cagttggatgaaagggaacacacaatagaagagtggaaagaattgatatacaaagaagtt
atggacttggaggagagaaccaagaatggagttatacgggggcagccctctcctttaggt
gcagcagtgatcaatggctctcagcatccatcgtcatcatcgtctgtcaatgatgtgtct
tcaatgtcaacagatccgactttggcctcggatacagacagcagtctagaagcatcagct
ggacctctgggctgctgtagatga

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