KEGG   Sus scrofa (pig): 396755Help
Entry
396755            CDS       T01009                                 

Gene name
INSR
Definition
(RefSeq) insulin receptor isoform X1
  KO
K04527  
insulin receptor [EC:2.7.10.1]
Organism
ssc  Sus scrofa (pig)
Pathway
MAPK signaling pathway
Ras signaling pathway
Rap1 signaling pathway
cGMP-PKG signaling pathway
HIF-1 signaling pathway
FoxO signaling pathway
Phospholipase D signaling pathway
mTOR signaling pathway
PI3K-Akt signaling pathway
AMPK signaling pathway
Longevity regulating pathway
Longevity regulating pathway - multiple species
Adherens junction
Insulin signaling pathway
Ovarian steroidogenesis
Regulation of lipolysis in adipocytes
Type II diabetes mellitus
Insulin resistance
Non-alcoholic fatty liver disease (NAFLD)
Aldosterone-regulated sodium reabsorption
Module
PI3K-Akt signaling
Brite
KEGG Orthology (KO) [BR:ssc00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    396755 (INSR)
   04015 Rap1 signaling pathway
    396755 (INSR)
   04010 MAPK signaling pathway
    396755 (INSR)
   04066 HIF-1 signaling pathway
    396755 (INSR)
   04068 FoxO signaling pathway
    396755 (INSR)
   04072 Phospholipase D signaling pathway
    396755 (INSR)
   04022 cGMP - PKG signaling pathway
    396755 (INSR)
   04151 PI3K-Akt signaling pathway
    396755 (INSR)
   04152 AMPK signaling pathway
    396755 (INSR)
   04150 mTOR signaling pathway
    396755 (INSR)
 Cellular Processes
  Cellular community - eukaryotes
   04520 Adherens junction
    396755 (INSR)
 Organismal Systems
  Endocrine system
   04910 Insulin signaling pathway
    396755 (INSR)
   04923 Regulation of lipolysis in adipocyte
    396755 (INSR)
   04913 Ovarian Steroidogenesis
    396755 (INSR)
  Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    396755 (INSR)
  Aging
   04211 Longevity regulating pathway - mammal
    396755 (INSR)
   04213 Longevity regulating pathway - multiple species
    396755 (INSR)
 Human Diseases
  Endocrine and metabolic diseases
   04930 Type II diabetes mellitus
    396755 (INSR)
   04932 Non-alcoholic fatty liver disease (NAFLD)
    396755 (INSR)
   04931 Insulin resistance
    396755 (INSR)
Enzymes [BR:ssc01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     396755 (INSR)
Protein kinases [BR:ssc01001]
 Tyrosine protein kinases
  InsR family [OT]
   396755 (INSR)
Enzyme-linked receptors [BR:ssc01020]
 Receptor tyrosine kinases
  RTK class II (Insulin receptor family)
   396755 (INSR)
Cytokine receptors [BR:ssc04050]
 Receptor tyrosine kinase
  RTK class II (Insulin receptor family)
   396755 (INSR)
CD molecules [BR:ssc04090]
 Proteins
  396755 (INSR)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GeneID: 
NCBI-ProteinID: 
Ensembl: 
Vega: 
Position
2
AA seq 1382 aa AA seqDB search
MGAGGRRGAAALPLLVAVAALLVSAAGHLYPGEVCPGMDIRNNLTRLHELANCSVIEGHL
QILLMFKTRPEDFRDLSFPKLIMITDYLLLFRVYGLESLKDLFPNLTVIRGSRLFFNYAL
VIFEMVHLKELGLYNLMNITRGAVRIEKNNELCYLATIDWSRILDSVEDNYIVLNKDDNE
ECGDICPGTAKGKTNCPATVINGQFVERCWTHSHCQKVCPTICKSHGCTAEGLCCHSECL
GNCSEPDDPTKCVACRNFYLDGRCVETCPPPYYHFQDWRCVNFSFCQDLHNKCKNSRRQG
CHQYVIHNNKCIPECPSGYTMNSSNLMCTPCLGPCPKVCHLLEGEKTIDSVTSAQELRGC
TIINGSLIINIRGGNNLAAELEANLGLIEEISGYLKIRRSYALVSLSFFRKLRLIRGETL
EIGNYSFYALDNQNLRQLWDWSKHNLTITQGKLFFHYNPKLCLSEIHKMEEVSGTKGRQE
RNDIALKTNGDQASCENELLKFSYIRTSYDKILLKWEPYWPPDFRDLLGFMLFYKEAPYQ
NVTEFDGQDACGSNSWTVVDIDPPTRSNDPKSQNHPGWLMRGLKPWTQYAIFVKTLVTFS
DERRTYGAKSDIIYVQTDATNPSVPLDPISVSNSSSQIILKWKPPSDPNGNITHYLVFWE
RQAEDSELYELDYCLKGLKLPSRTWSPPFETEGSQKHNQSEYEESSGECCSCPKTDSQIL
KELEESSFRKTFEDYLHNVVFIPRKSSSGPAAEDARPSRKRRALGDVGNITAAVPTIPGF
SNTSSTSTPTSSEEHRPFEKVVNRESLVISGLRHFTGYRIELQACNQDAPEERCSVAAYV
SARTMPEAKADDIIGPVTHEIFENNVVHLMWQEPKEPNGLIVLYEVSYRRYGDEELHLCV
SRRHFALERGCRLRGLPPGNYSVRVRATSLAGNGSWTEATYFYVTDYLDVPSNIAKIIIG
PLIFVFLFSVVIGSIYLFLRKRQPDGPLGPLYASSNPEYLSASDVFPCSVYVPDEWEVPR
EKITLLRELGQGSFGMVYEGNARDIVKGEPETRVAVKTVNESASLRERIEFLNEASVMKG
FTCHHVVRLLGVVSKGQPTLVVMELMAHGDLKSYLRSLRPEAENNPGRPPPTLQEMIQMA
AEIADGMAYLNAKKFVHRDLAARNCMVAHDFTVKIGDFGMTRDIYETDYYRKGGKGLLPV
RWMAPESLKDGVFTTSSDMWSFGVVLWEITSLAEQPYQGLSNEQVLKFVMDGGYLDQPDN
CPERVTDLMRMCWQFNPKMRPTFLEIVDLLKDDLHPSFPEVSFFHSEENKAPESEELEME
FEDMESVPLDRSSHSQREEAGGRDGGSALGLKRNYEEHISYTHMNGGKKNGRILTLPRSN
PS
NT seq 4149 nt NT seq  +upstreamnt  +downstreamnt
atgggcgctgggggcaggcggggggcggcggccctgccgctgctggtggccgttgccgcg
ctgctggtgagcgccgcgggccacctgtaccctggagaggtgtgcccagggatggatatc
cggaataaccttacacggctgcacgagttggccaactgctcggtcatcgaaggacatttg
cagatcctgttgatgttcaaaacgcggcccgaggatttccgagacctcagtttccccaaa
ctcatcatgatcactgattacttgctgctcttccgggtctacgggctggagagcctgaag
gacctgttccccaacctcaccgtcatccggggctcacgcctcttctttaactatgcgctg
gtcatctttgagatggttcacttgaaggagcttggcctctacaatttgatgaacatcacc
aggggtgctgtccgcatcgagaagaacaatgagctctgctacctggcgaccattgactgg
tcgcgcatcctggactctgtggaggataattacattgtgctgaacaaagacgacaacgag
gagtgtggggacatttgcccaggcactgcgaagggcaagaccaattgccctgccaccgtc
atcaatgggcaatttgtcgagcggtgttggacgcacagtcactgccagaaagtgtgcccg
accatctgtaagtcgcacggctgcactgctgagggcctctgctgtcacagcgagtgtttg
ggcaactgctctgagccagacgaccccaccaagtgcgtggcctgccgcaacttctacctg
gacggcagatgcgtggagacctgcccgcccccctactaccacttccaagactggcgctgc
gtgaacttcagcttctgccaggacctgcacaacaaatgcaagaactcaaggaggcagggc
tgccaccagtacgtcattcacaacaacaagtgtatccctgagtgcccctcagggtacacg
atgaattccagcaacttgatgtgcactccgtgcctaggcccctgtcccaaagtgtgtcac
ctcctggaaggcgagaagaccatcgactcagtgacatccgcccaggagctccgaggctgc
accattatcaacgggagcctaatcatcaacattcgaggaggcaacaacctggcagccgaa
ctagaggccaaccttggactcattgaggagatttcagggtacctgaaaatccgccgatcc
tatgccctcgtgtcactttccttcttccggaagttgcgtctgatccgaggggagacgttg
gaaattgggaactattctttctatgccttggacaaccagaacctaaggcaactgtgggac
tggagcaaacacaacctcaccatcactcaggggaaactcttcttccattataatcccaaa
ctctgcttgtcggaaattcacaagatggaggaagtttctggaaccaaggggcgccaggag
agaaatgatattgccctgaagaccaatggggaccaggcgtcctgtgaaaatgagttactt
aaattttcttacattcggacatcttatgacaagatcttgctgaagtgggagccgtattgg
ccccccgacttccgagacctcctggggttcatgctcttctacaaagaggccccttatcag
aacgtgacggagtttgacgggcaggatgcgtgtggctccaacagctggacggtggtggac
attgacccgcctacgaggtccaatgaccccaagtcccagaaccatcctgggtggctgatg
cgtggtctcaagccctggacccagtatgccatctttgtcaagactttggtcaccttttct
gatgaacgacgcacctatggagccaagagtgacatcatctacgtccagacagatgccaca
aatccttccgtccccctggatcccatctcggtttctaattcctcgtcccagatcattctg
aagtggaagcccccctctgaccccaacggcaacatcacacactacctggtgttctgggag
aggcaggcggaggacagtgagctgtatgaactggattattgcctcaaagggttgaagctg
ccctcccggacctggtccccaccattcgagactgaggggtcccagaagcacaatcagagt
gagtacgaggaatcctctggggaatgctgctcctgcccaaagaccgactcacagatcctc
aaggagctggaggaatcatcattcaggaaaacgtttgaagattacctacacaatgtggta
ttcatccccagaaaatcctcttcaggccctgctgccgaggacgctaggccatccaggaaa
cgcagggcccttggtgacgtggggaacataacggcggccgtgcccaccattccgggtttc
tccaacacctcctccaccagcactcccacgagctcagaggagcacagaccctttgagaag
gtggtgaacagagagtcactggtcatctctggcctgcgtcacttcactggctatcgcatt
gagctgcaggcttgcaaccaagatgcccccgaagagaggtgcagtgtggctgcgtatgtc
agcgccaggaccatgcctgaagccaaggcagatgatatcattggccctgtgacccatgaa
atcttcgagaacaacgtcgttcacttgatgtggcaggagccgaaggaacccaatggtctg
attgtgctgtacgaagtgagttaccgacgatacggtgatgaggagctgcatctctgcgtc
tcccgcaggcattttgctctggagcgaggctgcaggctacgcgggctgccacctgggaat
tacagcgttcgagttcgggccacctccctggcgggtaatggctcctggacagaggccacc
tatttctacgtgacagactatttagacgtcccatcaaatattgcaaaaattatcattggc
cccctcatctttgtctttctcttcagtgttgtgattggaagcatttatctattcctgagg
aagaggcagccggatgggccactgggaccattgtatgcttcttcgaaccccgagtacctc
agtgccagcgatgtatttccatgttctgtgtacgtgccggacgagtgggaggtgcctcgg
gagaagatcacgctcctgcgcgagctggggcagggctccttcggcatggtgtacgaggga
aacgccagggacatcgtcaagggtgagccggagacccgtgtggcggtgaagacggtcaac
gagtcggccagcctgcgagagcggatcgagtttctcaacgaggcctccgtcatgaagggc
ttcacctgccaccatgtggtccgcctcctgggggtggtgtccaaaggccagccaacactg
gtggtgatggagttgatggctcacggagacttaaagagttacctgcgttccctgcggccg
gaggctgagaataaccccggccgccctccccctaccctgcaagagatgattcagatggca
gcagagattgctgatgggatggcatacctgaacgccaagaagtttgtacaccgggacctc
gccgcacgaaattgcatggtcgcccatgattttaccgtcaaaatcggagactttggaatg
accagagacatctacgaaacggattactaccggaaagggggcaagggtctactgcccgtg
cgatggatggcacccgaatccctgaaggacggggtctttaccacttcttccgacatgtgg
tcctttggcgtcgtcctttgggaaattaccagcttggcagaacagccttaccaaggcctt
tcaaacgagcaggtgttgaaatttgtcatggatggaggctatctggatcaacctgacaat
tgtccagagagagtcaccgacctgatgcgcatgtgctggcagttcaaccccaagatgcgg
ccgaccttcctggagattgttgacctgctcaaggacgacctgcaccccagctttcccgaa
gtctccttcttccacagcgaggagaacaaagcacccgagagcgaggagctggagatggag
tttgaggacatggagagcgtccccctggaccggtcctcacactcgcagagggaggaggcc
gggggtcgggatggagggtccgcgctggggctaaagaggaactatgaggagcacatctcc
tacacccacatgaacggaggcaagaaaaatggccggattctgactctgccccggtcaaat
ccttcctaa

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