KEGG   Sus scrofa (pig): 397202
Entry
397202            CDS       T01009                                 
Symbol
JAK1
Name
(RefSeq) tyrosine-protein kinase JAK1
  KO
K11217  Janus kinase 1 [EC:2.7.10.2]
Organism
ssc  Sus scrofa (pig)
Pathway
ssc01521  EGFR tyrosine kinase inhibitor resistance
ssc04151  PI3K-Akt signaling pathway
ssc04217  Necroptosis
ssc04380  Osteoclast differentiation
ssc04550  Signaling pathways regulating pluripotency of stem cells
ssc04620  Toll-like receptor signaling pathway
ssc04621  NOD-like receptor signaling pathway
ssc04630  JAK-STAT signaling pathway
ssc04658  Th1 and Th2 cell differentiation
ssc04659  Th17 cell differentiation
ssc05140  Leishmaniasis
ssc05145  Toxoplasmosis
ssc05152  Tuberculosis
ssc05160  Hepatitis C
ssc05161  Hepatitis B
ssc05162  Measles
ssc05163  Human cytomegalovirus infection
ssc05164  Influenza A
ssc05165  Human papillomavirus infection
ssc05166  Human T-cell leukemia virus 1 infection
ssc05167  Kaposi sarcoma-associated herpesvirus infection
ssc05168  Herpes simplex virus 1 infection
ssc05169  Epstein-Barr virus infection
ssc05171  Coronavirus disease - COVID-19
ssc05200  Pathways in cancer
ssc05203  Viral carcinogenesis
ssc05212  Pancreatic cancer
ssc05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:ssc00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    397202 (JAK1)
   04151 PI3K-Akt signaling pathway
    397202 (JAK1)
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    397202 (JAK1)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    397202 (JAK1)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    397202 (JAK1)
   04621 NOD-like receptor signaling pathway
    397202 (JAK1)
   04658 Th1 and Th2 cell differentiation
    397202 (JAK1)
   04659 Th17 cell differentiation
    397202 (JAK1)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    397202 (JAK1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    397202 (JAK1)
   05203 Viral carcinogenesis
    397202 (JAK1)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    397202 (JAK1)
  09162 Cancer: specific types
   05212 Pancreatic cancer
    397202 (JAK1)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    397202 (JAK1)
   05161 Hepatitis B
    397202 (JAK1)
   05160 Hepatitis C
    397202 (JAK1)
   05171 Coronavirus disease - COVID-19
    397202 (JAK1)
   05164 Influenza A
    397202 (JAK1)
   05162 Measles
    397202 (JAK1)
   05168 Herpes simplex virus 1 infection
    397202 (JAK1)
   05163 Human cytomegalovirus infection
    397202 (JAK1)
   05167 Kaposi sarcoma-associated herpesvirus infection
    397202 (JAK1)
   05169 Epstein-Barr virus infection
    397202 (JAK1)
   05165 Human papillomavirus infection
    397202 (JAK1)
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    397202 (JAK1)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    397202 (JAK1)
   05140 Leishmaniasis
    397202 (JAK1)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    397202 (JAK1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:ssc01001]
    397202 (JAK1)
Enzymes [BR:ssc01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.2  non-specific protein-tyrosine kinase
     397202 (JAK1)
Protein kinases [BR:ssc01001]
 Non-receptor tyrosine kinases
  JAK family [OT]
   397202 (JAK1)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase Jak1_Phl FERM_F2 FERM_F1 ABC1 SH2 RIO1 FERM_C_FAK1
Other DBs
NCBI-GeneID: 397202
NCBI-ProteinID: NP_999279
Ensembl: ENSSSCG00000003809
Vega: OTTSUSG00000002956
UniProt: Q9TTJ1
Position
6:147320288..147567188
AA seq 1141 aa
MAFCAKMRSSKKTEVNLEAPEPGVEVLFYLSDREPLRLGGGEYTAEEVCIKAAQECCISP
LCHNLFALYDESTKLWYAPNRTITVDDKTSVRLHYRMRFYFTNWHGTNDNEQSVWRHSPK
KQKNGYEKKKVPDATPLLDASSLEYLFAQGQYDLVKCLAPIRDPKTEQDGHDIENECLGM
AVLAISHYAMMKKMQLPELPKDISYKRYIPETLNKSIRQRNLLTRMRINNVFKDFLKEFN
NKTICDSSVSTHDLKVKYLATLETLTKHYGAEIFETSMLLISSENEMSRFHPNDGGNVLY
EVMVTGNLGIQWRQKPNVVPIEKEKNKLKRKKLESKHKKDEEKNKIREEWNNFSYFPEIT
HIVIKESVVSINKQDNKKMELKLSSHEEALSFVSLIDGYFRLTADAHHYLCTDVAPPLIV
HNIQNGCHGPICTEYAINKLRQEGSEEGMYVLRWSCTDFDNILMTVTCFEKSEVLGGQKQ
FKNFQIEVQKGRYSLHGSDRSFPSLGDLMSHLKKQILRTDNISFVLKRCCQPKPREISNL
LVATKKAQEWQPVYTMSQLSFDRILKNDIMQGEHLGRGTRTHIYSGTLMDYKDDEGTSEE
KRKIKVILKVLDPSHRDISLAFFEAASMMRQVSHKHIVYLYGVCVRDVENIMVEEFVEGG
PLDLFMHRKSDVLTTPWKFKVAKQLASALSYLEDKDLVHGNVCTKNLLLAREGIDSECGP
FIKLSDPGIPITVLSRQECIERIPWIAPECVEDSKNLSVAADKWSFGTTLWEICYNGEIP
LKDKTLIEKERFYESRCRPVTPSCKELADLMTRCMNYDPNQRPFFRAIMRDINKLEEQNP
DIVSEKKPATEVDPTHFEKRFLKRIRDLGEGHFGKVELCRYDPEGDNTGEQVAVKSLKPE
SGGNHIADLKKEIEILRNLYHENIVKYKGICTEDGGNGIKLIMEFLPSGSLKEYLPKNKN
KINLKQQLKYAVQICKGMDYLGSRQYVHRDLAARNVLVESEHQVKIGDFGLTKAIETDKE
YYTVKDDRDSPVFWYAPECLIQCKFYIASDVWSFGVTLHELLTYCDSDSSPMALFLKMIG
PTHGQMTVTRLVNTLKEGKRLPCPPNCPEEVYQLMRKCWEFQPSNRTTFQNLIEGFEALL
K
NT seq 3426 nt   +upstreamnt  +downstreamnt
atggctttttgtgctaaaatgaggagctccaagaagaccgaggtgaatctggaggcccct
gagccgggggtggaagtgctcttctatctgtcggatagggagcccctccggctgggcggc
ggggagtacacggccgaggaggtgtgcatcaaggcggcgcaggaatgctgtatctctcct
ctgtgtcacaacctctttgccctgtatgatgagagcaccaagctctggtacgctccaaat
cgcaccatcaccgtcgatgacaagacgtcagttcggctccactaccggatgaggttctat
ttcaccaactggcatgggaccaatgataatgagcagtcggtatggcggcattctccaaag
aaacagaaaaatggctacgagaaaaaaaaagttccagatgcaacccctctccttgatgcc
agctcattggaatatctctttgctcaggggcagtacgatttggtcaaatgcctggctccc
attcgagaccccaagacggagcaggacgggcatgatattgagaacgagtgtctgggcatg
gctgtgttggccatctcccactatgccatgatgaagaagatgcagttgccagaacttccc
aaggacatcagctacaagcgatatattccagaaacattgaataagtccatcagacagagg
aatcttcttacgaggatgcggataaataatgttttcaaggatttcctaaaggagtttaac
aacaagaccatttgtgacagtagcgtgtctacgcatgacctgaaggtgaaatacctggct
accttggaaactttgaccaaacattatggtgctgaaatatttgagacgtctatgttactg
atttcatcggaaaatgagatgagtcggtttcatccaaatgacggtggaaatgttctctat
gaggtgatggtgactggaaatctcgggatccagtggaggcagaaacccaatgttgttccc
attgaaaaggaaaaaaataaactgaaacgaaaaaaactggaaagtaaacacaagaaggat
gaggaaaaaaacaaaatccgggaagagtggaacaatttttcgtacttccctgagatcact
cacattgtcatcaaggagtctgtggtcagcattaacaagcaggacaacaaaaaaatggaa
ctgaagctctcttcccacgaggaggccttgtccttcgtgtccctgatagacggctacttc
cggctcacagcagatgcccatcattacctctgcaccgacgtggctcccccgttgattgtc
cacaacatacagaatggttgtcacggtccaatctgcacagagtacgccatcaataaactg
cggcaagagggcagcgaggaggggatgtacgtgctgcggtggagctgcactgactttgac
aacatcctcatgaccgtcacctgctttgagaagtccgaggtgctaggtggccagaagcag
ttcaagaacttccagattgaggtgcagaagggccgctacagcctgcatggctcggaccgc
agctttcccagcctcggggacctcatgagccacctgaagaagcagatcctgcgcacggac
aacatcagcttcgtgctgaagcgctgctgccagcccaagccccgagaaatctccaatttg
ctggtggccaccaagaaagcccaggagtggcagcccgtctacaccatgagccagctgagt
ttcgatcggatccttaagaatgacattatgcaaggcgagcaccttgggagaggcactcgg
acgcacatctactccggcaccctcatggactacaaggacgacgaagggacttccgaagag
aagagaaaaataaaagtgatcctcaaagtcttagaccccagccacagggacatctctctg
gccttcttcgaggcagccagcatgatgaggcaggtctcccataagcacatcgtgtacctc
tacggcgtctgtgtccgggacgtggagaacatcatggtggaggagtttgtggagggggga
cccctggatctcttcatgcaccggaaaagcgacgtcctcaccacaccctggaagttcaaa
gttgccaaacagctggccagtgccctgagttacctggaggataaagacctggtccatgga
aatgtgtgcactaaaaacctcctcctggcccgtgagggcatcgacagcgagtgcggcccg
ttcatcaagctcagtgaccccggcatccccatcacggtgctgtccaggcaagagtgcata
gaacgaatcccgtggatcgctcccgaatgtgttgaggactccaagaacctgagtgtggct
gcggacaaatggagctttggaaccacgctctgggagatctgctacaatggcgagatcccc
ttgaaagacaagacactcattgagaaagagagattctatgaaagccgatgtaggccggtg
accccatcttgtaaggagctggctgaccttatgacccgctgcatgaactacgaccccaac
cagagacccttcttccgagccatcatgagagacatcaataagctggaggaacagaatcca
gacattgtatcagaaaaaaagccagcaactgaggtggatcccacacattttgaaaagcgg
ttcttaaagaggatccgtgacctgggagagggccactttgggaaggtcgagctttgtagg
tatgaccccgagggggacaacacaggggagcaggtggctgtcaagtccctgaagcctgag
agcggaggaaaccacatagctgatctgaagaaggagattgaaatcttgagaaacctttat
cacgagaacattgtcaagtataaaggcatttgcacagaggacggaggaaatggtattaag
cttatcatggaattcctgccttcgggaagccttaaggagtatcttccaaagaataaaaac
aaaatcaacctcaaacagcagttaaaatacgccgttcagatttgtaaggggatggactat
ttgggttctcggcaatacgttcaccgggacttggcagcaagaaatgttcttgtcgagagt
gaacaccaagtgaaaattggagacttcggtctcaccaaagccatcgaaaccgataaggag
tactacacagtcaaggacgatcgggacagccctgtgttttggtatgctccggagtgttta
attcagtgtaaattttacatcgcctccgatgtctggtctttcggggtgactctgcatgag
ctgctcacttactgtgattcggattccagtcccatggcgttgttcctgaaaatgataggc
ccaactcatggccagatgacggtaacaagacttgtgaatacattaaaagaaggaaaacgt
ttgccttgtccacctaactgtccagaagaggtttatcaactgatgagaaaatgctgggaa
ttccaaccatctaatcggacaacctttcagaaccttattgaaggatttgaagcactttta
aaataa

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (28)   
   KEGG PATHWAY (28)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (12)   
   KEGG ORTHOLOGY (1)   
   RefGene (6)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   VEGA (1)   
Protein sequence (14)   
   UniProt (1)   
   RefSeq(pep) (13)   
DNA sequence (33)   
   RefSeq(nuc) (13)   
   GenBank (10)   
   EMBL (10)   
Protein domain (9)   
   Pfam (9)   
All databases (101)   

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