KEGG   Sus scrofa (pig): 397652Help
Entry
397652            CDS       T01009                                 

Gene name
PRKACA, PKA
Definition
protein kinase, cAMP-dependent, catalytic, alpha
Orthology
K04345  
protein kinase A [EC:2.7.11.11]
Organism
ssc  Sus scrofa (pig)
Pathway
MAPK signaling pathway
Ras signaling pathway
Calcium signaling pathway
cAMP signaling pathway
Chemokine signaling pathway
Oocyte meiosis
Apoptosis
Adrenergic signaling in cardiomyocytes
Vascular smooth muscle contraction
Wnt signaling pathway
Hedgehog signaling pathway
Gap junction
Platelet activation
Circadian entrainment
Long-term potentiation
Retrograde endocannabinoid signaling
Glutamatergic synapse
Cholinergic synapse
Serotonergic synapse
GABAergic synapse
Dopaminergic synapse
Olfactory transduction
Taste transduction
Inflammatory mediator regulation of TRP channels
Insulin signaling pathway
Insulin secretion
GnRH signaling pathway
Ovarian steroidogenesis
Progesterone-mediated oocyte maturation
Estrogen signaling pathway
Melanogenesis
Thyroid hormone synthesis
Thyroid hormone signaling pathway
Oxytocin signaling pathway
Endocrine and other factor-regulated calcium reabsorption
Vasopressin-regulated water reabsorption
Salivary secretion
Gastric acid secretion
Bile secretion
Parkinson's disease
Prion diseases
Cocaine addiction
Amphetamine addiction
Morphine addiction
Amoebiasis
HTLV-I infection
Epstein-Barr virus infection
Viral carcinogenesis
Proteoglycans in cancer
Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:ssc00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    397652 (PRKACA)
   04010 MAPK signaling pathway
    397652 (PRKACA)
   04310 Wnt signaling pathway
    397652 (PRKACA)
   04340 Hedgehog signaling pathway
    397652 (PRKACA)
   04020 Calcium signaling pathway
    397652 (PRKACA)
   04024 cAMP signaling pathway
    397652 (PRKACA)
 Cellular Processes
  Cell growth and death
   04114 Oocyte meiosis
    397652 (PRKACA)
   04210 Apoptosis
    397652 (PRKACA)
  Cellular commiunity
   04540 Gap junction
    397652 (PRKACA)
 Organismal Systems
  Immune system
   04611 Platelet activation
    397652 (PRKACA)
   04062 Chemokine signaling pathway
    397652 (PRKACA)
  Endocrine system
   04911 Insulin secretion
    397652 (PRKACA)
   04910 Insulin signaling pathway
    397652 (PRKACA)
   04912 GnRH signaling pathway
    397652 (PRKACA)
   04913 Ovarian Steroidogenesis
    397652 (PRKACA)
   04915 Estrogen signaling pathway
    397652 (PRKACA)
   04914 Progesterone-mediated oocyte maturation
    397652 (PRKACA)
   04921 Oxytocin signaling pathway
    397652 (PRKACA)
   04918 Thyroid hormone synthesis
    397652 (PRKACA)
   04919 Thyroid hormone signaling pathway
    397652 (PRKACA)
   04916 Melanogenesis
    397652 (PRKACA)
  Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    397652 (PRKACA)
   04270 Vascular smooth muscle contraction
    397652 (PRKACA)
  Digestive system
   04970 Salivary secretion
    397652 (PRKACA)
   04971 Gastric acid secretion
    397652 (PRKACA)
   04976 Bile secretion
    397652 (PRKACA)
  Excretory system
   04962 Vasopressin-regulated water reabsorption
    397652 (PRKACA)
   04961 Endocrine and other factor-regulated calcium reabsorption
    397652 (PRKACA)
  Nervous system
   04724 Glutamatergic synapse
    397652 (PRKACA)
   04727 GABAergic synapse
    397652 (PRKACA)
   04725 Cholinergic synapse
    397652 (PRKACA)
   04728 Dopaminergic synapse
    397652 (PRKACA)
   04726 Serotonergic synapse
    397652 (PRKACA)
   04720 Long-term potentiation
    397652 (PRKACA)
   04723 Retrograde endocannabinoid signaling
    397652 (PRKACA)
  Sensory system
   04740 Olfactory transduction
    397652 (PRKACA)
   04742 Taste transduction
    397652 (PRKACA)
   04750 Inflammatory mediator regulation of TRP channels
    397652 (PRKACA)
  Environmental adaptation
   04713 Circadian entrainment
    397652 (PRKACA)
 Human Diseases
  Cancers
   05205 Proteoglycans in cancer
    397652 (PRKACA)
   05203 Viral carcinogenesis
    397652 (PRKACA)
  Neurodegenerative diseases
   05012 Parkinson's disease
    397652 (PRKACA)
   05020 Prion diseases
    397652 (PRKACA)
  Substance dependence
   05030 Cocaine addiction
    397652 (PRKACA)
   05031 Amphetamine addiction
    397652 (PRKACA)
   05032 Morphine addiction
    397652 (PRKACA)
  Cardiovascular diseases
   05414 Dilated cardiomyopathy (DCM)
    397652 (PRKACA)
  Infectious diseases
   05166 HTLV-I infection
    397652 (PRKACA)
   05169 Epstein-Barr virus infection
    397652 (PRKACA)
   05146 Amoebiasis
    397652 (PRKACA)
Enzymes [BR:ssc01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.11  cAMP-dependent protein kinase
     397652 (PRKACA)
Protein kinases [BR:ssc01001]
 Serine/threonine protein kinases: AGC group
  PKA family
   397652 (PRKACA)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Ensembl: 
UniProt: 
Structure
PDB: 

Jmol
Position
2
AA seq 351 aa AA seqDB search
MGNAAAAKKGSEQESVKEFLAKAKEDFLKKWENPAQNTAHLDQFERIKTLGTGSFGRVML
VKHKETGNHFAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMV
MEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGY
IQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFF
ADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFAT
TDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFSEF
NT seq 1056 nt NT seq  +upstreamnt  +downstreamnt
atgggcaacgccgccgccgccaagaagggcagcgagcaggagagcgtgaaagagttctta
gccaaagccaaagaagattttcttaaaaaatgggaaaatcctgctcagaatacagcccat
ttggatcaatttgaacgaatcaagaccctcggcacgggctccttcgggcgggtgatgctg
gtgaagcacaaggagactgggaaccactttgccatgaagatcctcgacaaacagaaggtg
gtgaagctgaaacagattgagcacaccctgaatgaaaagcgcatcctgcaagcagtcaac
ttcccgttccttgtcaaactcgagttctccttcaaggacaactcaaatttatacatggtc
atggaatatgtgcctggtggggagatgttctcacacctgcggaggatcgggaggttcagt
gagccccatgcccgcttctacgcggcccagattgtcctgaccttcgagtacctgcactcg
cttgatctcatctaccgggacctgaagccggagaaccttctcatcgaccagcagggctac
attcaggtgacagacttcggttttgccaaacgtgtgaaaggccgcacctggactttgtgt
gggacacccgagtacctggcccctgagatcatcctgagtaaaggctacaacaaagctgtg
gactggtgggccctgggggttctcatctatgagatggccgctggctacccgcccttcttc
gctgaccagcccatccagatctacgagaagattgtctccgggaaggtgcggttcccgtcc
cacttcagctccgacctgaaggatctgcttcggaacctcctgcaggtggacctcaccaaa
cgctttgggaaccttaagaacggagtcaatgacatcaagaaccacaagtggtttgccacg
actgactggattgccatctaccagaggaaggtggaagctcccttcataccaaagtttaaa
ggccctggggacacgagtaactttgatgactatgaggaagaagagatccgagtctccatc
aatgagaagtgtggcaaggagttttctgagttttag

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