KEGG   MODULE: ssc_M00110Help
Entry
ssc_M00110        Pathway   Module                                 

Name
C19/C18-Steroid hormone biosynthesis, pregnenolone => androstenedione => estrone
Definition
K00512 (K00070,K01822) K07434
Module map
ssc_M00110

Orthology
K00512  
steroid 17alpha-monooxygenase / 17alpha-hydroxyprogesterone deacetylase [EC:1.14.14.19 1.14.14.32] [RN:R03783 R08517]
K00070  
3beta-hydroxy-delta5-steroid dehydrogenase [EC:1.1.1.145] [RN:R01837]
K01822  
steroid delta-isomerase [EC:5.3.3.1] [RN:R01837]
K07434  
cytochrome P450, family 19, subfamily A (aromatase) [EC:1.14.14.14] [RN:R01840 R04759 R02351]
Ortholog tableTaxonomy
Class
Pathway module; Carbohydrate and lipid metabolism; Sterol biosynthesis
BRITE hierarchy
Pathway
ssc00140  Steroid hormone biosynthesis
Organism
Sus scrofa (pig) [GN:ssc]
Gene
403330  CYP17A1; steroid 17-alpha-hydroxylase/17,20 lyase precursor [KO:K00512]
403331  CYP19A1; aromatase 1 [KO:K07434]
403332  CYP19A2; aromatase 2 [KO:K07434]
403333  CYP19A3; aromatase 3 [KO:K07434]
445539  HSD3B1; 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase [KO:K00070]
Reaction
Compound
C01953  Pregnenolone
C05138  17alpha-Hydroxypregnenolone
C01227  Dehydroepiandrosterone
C00280  Androstenedione
C05290  19-Hydroxyandrost-4-ene-3,17-dione
C05297  19-Oxoandrost-4-ene-3,17-dione
C00468  Estrone
Other DBs
BSID: 446218
KO module

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