KEGG   MODULE: ssc_M00110Help
Entry
ssc_M00110        Pathway   Module                                 

Name
C19/C18-Steroid hormone biosynthesis, pregnenolone => androstenedione => estrone
Definition
K00512 (K00070,K01822) K07434
Module map
ssc_M00110

Orthology
K00512  
cytochrome P450, family 17, subfamily A (steroid [EC:1.14.99.9] [RN:R03783 R08517]
K00070  
3beta-hydroxy-delta5-steroid dehydrogenase [EC:1.1.1.145] [RN:R01837]
K01822  
steroid delta-isomerase [EC:5.3.3.1] [RN:R01837]
K07434  
cytochrome P450, family 19, subfamily A (aromatase) [EC:1.14.14.14] [RN:R01840 R04759 R02351]
Ortholog tableTaxonomy
Class
Pathway module; Carbohydrate and lipid metabolism; Sterol biosynthesis
BRITE hierarchy
Pathway
Steroid hormone biosynthesis
Organism
Sus scrofa (pig) [GN:ssc]
Gene
403330  
CYP17A1; cytochrome P450 17A1 (EC:1.14.99.9 4.1.2.30) [KO:K00512]
403331  
CYP19A1; cytochrome P450 19A1 (EC:1.14.14.14) [KO:K07434]
403333  
CYP19A3; cytochrome P450 19A3 (EC:1.14.14.14) [KO:K07434]
445539  
HSD3B1; hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 (EC:1.1.1.145 5.3.3.1) [KO:K00070]
Reaction
Compound
C01953  
Pregnenolone
C05138  
17alpha-Hydroxypregnenolone
C01227  
Dehydroepiandrosterone
C00280  
Androstenedione
C05290  
19-Hydroxyandrost-4-ene-3,17-dione
C05297  
19-Oxoandrost-4-ene-3,17-dione
C00468  
Estrone
Other DBs
BSID: 
KO module

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