KEGG   Streptomyces alfalfae: A7J05_12305
Entry
A7J05_12305       CDS       T05110                                 
Symbol
kgd
Name
(GenBank) alpha-ketoglutarate decarboxylase
  KO
K01616  multifunctional 2-oxoglutarate metabolism enzyme [EC:2.2.1.5 4.1.1.71 1.2.4.2 2.3.1.61]
Organism
ssia  Streptomyces alfalfae
Pathway
ssia00020  Citrate cycle (TCA cycle)
ssia00630  Glyoxylate and dicarboxylate metabolism
ssia00785  Lipoic acid metabolism
ssia01100  Metabolic pathways
ssia01110  Biosynthesis of secondary metabolites
ssia01120  Microbial metabolism in diverse environments
ssia01200  Carbon metabolism
ssia01210  2-Oxocarboxylic acid metabolism
Module
ssia_M00009  Citrate cycle (TCA cycle, Krebs cycle)
ssia_M00011  Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:ssia00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00020 Citrate cycle (TCA cycle)
    A7J05_12305 (kgd)
   00630 Glyoxylate and dicarboxylate metabolism
    A7J05_12305 (kgd)
  09108 Metabolism of cofactors and vitamins
   00785 Lipoic acid metabolism
    A7J05_12305 (kgd)
Enzymes [BR:ssia01000]
 1. Oxidoreductases
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.4  With a disulfide as acceptor
    1.2.4.2  oxoglutarate dehydrogenase (succinyl-transferring)
     A7J05_12305 (kgd)
 2. Transferases
  2.2  Transferring aldehyde or ketonic groups
   2.2.1  Transketolases and transaldolases
    2.2.1.5  2-hydroxy-3-oxoadipate synthase
     A7J05_12305 (kgd)
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.61  dihydrolipoyllysine-residue succinyltransferase
     A7J05_12305 (kgd)
 4. Lyases
  4.1  Carbon-carbon lyases
   4.1.1  Carboxy-lyases
    4.1.1.71  2-oxoglutarate decarboxylase
     A7J05_12305 (kgd)
SSDB
Motif
Pfam: E1_dh 2-oxoacid_dh OxoGdeHyase_C Transket_pyr 2-oxogl_dehyd_N
Other DBs
NCBI-ProteinID: APY86393
UniProt: A0A1P8TFH6
Position
3081075..3084890
AA seq 1271 aa
MSPESPSNSSISTDQDGQGKDPAAAFGPNEWLVDEIYQQYLQDPNSVDRAWWDFFADYKP
GVGASVAAAPAKPAGDVAAGAAAPSAPAAQAAPAAPAAKAPAAQQAAPAPAPAAKPAAAA
PAPAAKPAAAKPAAKAEPAKEAPAKEAPAGPEYVTLRGPSAAVAKNMNASIEVPTATSVR
AVPVKLLFDNRIVINNHLKRARGGKISFTHLIGYAMVQAIKAMPSMNYSFVEKDGKPTLV
KPEHINFGLAIDLVKPNGDRQLVVAGIKKAETLNFFEFWQAYEDIVRRARDGKLGMDDFT
GVTVSLTNPGGLGTVHSVPRLMPGQSVIMGVGSMDYPAEFQGTSQDTLNKLGISKVMTLT
STYDHRVIQGAASGEFLRIVANLLLGEQDFYDEIFKALRIPYEPVRWFKDIDASHDDDVT
KAARVFELIHSYRVRGHVMADTDPLEYKQRKHPDLDITEHGLTLWDLEREFAVGGFAGKS
MMKLRDVLGVLRDSYCRTTGVEFMHIQDPKQRKWLQDRIERQHATKPEREEQLRILRRLN
AAEAFETFLQTKYVGQKRFSLEGGESVIPLLDAVIDSAAESRLDEVVIGMAHRGRLNVLA
NIVGKSYAQIFREFEGNLDPKSMHGSGDVKYHLGAEGTFTGLDGEQIKVSLAANPSHLEA
VDPVLEGIVRAKQDIINKGGTDFTVLPVALHGDAAFAGQGVVAETLNMSQLRGYRTGGTV
HIVINNQVGFTAAPESSRSSMYSTDVARMIEAPIFHVNGDDPEAVVRVARLAFEFRQAFN
KDVVIDLICYRRRGHNESDNPAFTQPLMYDLIDKKRSVRKLYTESLIGRGDITLEEAEQA
LQDYQGQLEKVFTEVREATSQPSPVEVPGPEAEFPVTVNTAISQEVVKRIAESQVNIPDR
VTVHPRLLPQLQRRAAMVEDGTIDWGMGETLAIGSLLMEGTPVRLAGQDSRRGTFGQRHA
VLIDRETGDDYTPLLYLSEDQARFNAYDSLLSEYAAMGFEYGYSLARPESLVMWEAQFGD
FVNGAQTVVDEFISSAEQKWGQTSGVTLLLPHGYEGQGPDHSSARPERFLQLCAQNNMTV
AMPTLPSNYFHLLRWQVHNPHHKPLVVFTPKWMLRLKAAASKTEEFTSGGFRPVIGDATV
DPNAVRKVVFCAGKLYYELEAERQKRGVTDTAIIRIERLYPLPGAELQEEISKFPNAEKY
LWAQEEPANQGAWPFIALNLIDHLDLAVGADIPHGERLRRISRPHGSSPAVGSKKRHEQE
QEQLLSEVFEA
NT seq 3816 nt   +upstreamnt  +downstreamnt
gtgtcgccagagtcccccagtaactcgagcatctcgaccgaccaagacgggcagggcaag
gaccctgccgccgccttcggtcccaatgagtggctcgtcgacgagatctatcagcagtac
ctccaggacccgaattcggtcgaccgagcctggtgggacttctttgccgactacaagcca
ggggtgggcgcctccgtggccgccgccccggcgaagccggcgggtgacgtggccgcgggg
gccgcggcccccagtgctcccgccgcccaggccgccccggccgcgcccgccgccaaggct
cccgccgcgcagcaggccgcgcccgcgcccgcccccgcggcgaagcccgccgcggccgct
ccggctcccgcggccaagccggccgccgcgaagcccgccgccaaggcggagcccgcgaag
gaggcccccgccaaggaggccccggccggtcccgagtacgtgacgctgcgcggcccgagc
gccgccgtcgcgaagaacatgaacgcctcgatcgaggtcccgacggcgacgtcggtccgc
gcggtcccggtgaagctgctcttcgacaaccgcatcgtcatcaacaaccacctcaagcgc
gcccgcggcgggaagatctccttcacgcacctcatcgggtacgcgatggtccaggccatc
aaggccatgccgtcgatgaactactccttcgtggagaaggacggcaagcccaccctggtc
aagccggagcacatcaacttcggcctcgccatcgacctggtgaagcccaacggcgaccgc
cagctcgtggtcgcgggcatcaagaaggccgagacgctgaacttcttcgagttctggcag
gcctacgaggacatcgtccgccgcgcccgcgacggcaagctcggcatggacgacttcacc
ggcgtcacggtctccctgaccaaccccggcggcctcggcaccgtccactccgtgccgcgt
ctgatgcccggccagtcggtcatcatgggcgtcggctccatggactaccccgcggagttc
cagggcacctcccaggacaccctgaacaagctcggcatctcgaaggtcatgacgctcacg
tcgacctacgaccaccgggtcatccagggcgccgcctccggcgagttcctgcggatcgtc
gcgaacctcctcctcggcgagcaggacttctacgacgagatcttcaaggcgctgcgcatc
ccctacgagccggtccgctggttcaaggacatcgacgcctcgcacgacgacgacgtcacg
aaggccgcccgcgtcttcgagctgatccactcctaccgcgtgcgcggccacgtcatggcc
gacaccgacccgctggagtacaagcagcgcaagcaccccgacctggacatcaccgagcac
ggcctcaccctgtgggacctggagcgggagttcgcggtcggcggtttcgccggcaagtcg
atgatgaagctgcgcgacgtcctcggcgtgctgcgcgactcgtactgccgcaccaccggc
gtcgagttcatgcacatccaggaccccaagcagcgcaagtggctccaggaccgcatcgag
cgccagcacgccacgaagccggagcgcgaggagcagctgcgcatcctgcgccggctgaac
gccgccgaggccttcgagacgttcctgcagacgaagtacgtcggccagaagcgcttctcc
ctggagggcggcgagtccgtcatcccgctgctcgacgcggtcatcgactccgccgccgag
tcgcgcctggacgaggtcgtcatcggcatggcccaccgcggccgcctgaacgtcctcgcg
aacatcgtcggcaagtcgtacgcgcagatcttccgcgagttcgagggcaacctcgacccg
aagtcgatgcacggctccggcgacgtgaagtaccacctgggcgccgagggcaccttcacc
ggtctggacggcgagcagatcaaggtctcgctggccgccaacccctcgcacctggaggcg
gtcgacccggtcctcgaaggcatcgtccgcgccaagcaggacatcatcaacaagggcggc
acggacttcacggtcctgccggtggccctccacggcgacgcggccttcgcgggccagggc
gtggtggccgagaccctgaacatgtcgcagctgcgcggttaccgcacgggcggcacggtc
cacatcgtcatcaacaaccaggtcggcttcaccgccgccccggagtcgtcccgctcgtcg
atgtactcgacggacgtggcgcggatgatcgaggcgccgatcttccacgtgaacggcgac
gacccggaggccgtggtccgcgtggcccgcctggccttcgagttccgtcaggcgttcaac
aaggacgtcgtgatcgacctcatctgctaccgccgccgcggtcacaacgagtcggacaac
ccggcgttcacccagccgctgatgtacgacctgatcgacaagaagcgctcggtgcgcaag
ctctacaccgagtccctcatcggtcgcggcgacatcaccctggaagaggccgagcaggcc
ctccaggactaccagggccagctggagaaggtcttcaccgaggtccgcgaggccacctcg
cagccctcgccggtggaggtcccgggtcccgaggccgagttccccgtcacggtgaacacc
gcgatctcccaggaggtcgtcaagcgcatcgccgagtcccaggtcaacatccccgaccgc
gtcaccgtgcacccgcgactgctcccgcagctccagcgccgcgcggccatggtcgaggac
ggcacgatcgactggggcatgggcgagaccctcgccatcggctcgctgctgatggagggc
accccggtgcgcctcgcgggccaggactcgcgccgcggcacgttcggccagcgccacgcg
gtcctcatcgaccgcgagaccggcgacgactacaccccgctgctctacctctccgaggac
caggcgcgcttcaacgcctacgactcgctcctctcggagtacgcggcgatgggcttcgag
tacggttactccctggcccgtcccgagtccctcgtgatgtgggaggcgcagttcggtgac
ttcgtcaacggcgcgcagaccgtcgtcgacgagttcatctcctccgccgagcagaagtgg
ggccagacgtccggcgtcacgctcctgctcccgcacggctacgagggccagggcccggac
cactcctcggcccgtcccgagcggttcctccagctctgcgcgcagaacaacatgacggtc
gcgatgccgaccctgccgtcgaactacttccacctcctgcggtggcaggtgcacaacccg
caccacaagccgctggtggtcttcaccccgaagtggatgctgcgcctcaaggccgcggcc
tccaagacggaggagttcacgtcgggcggcttccgcccggtcatcggcgacgccaccgtg
gacccgaacgcggtccgcaaggtcgtcttctgcgcgggcaagctctactacgagctggag
gccgagcggcagaagcgcggtgtcacggacacggcgatcatccgcatcgagcgcctgtac
ccgctgccgggtgcggagctccaggaggagatctccaagttcccgaacgccgaaaagtac
ctgtgggcgcaggaggagccggcgaatcagggcgcgtggcccttcatcgccctcaacctc
atcgaccacctggacctggcggtcggcgccgacatcccgcacggtgagcgtctgcgccgc
atctcgcggccgcacggctcgtcgccggcggtcggctcgaagaagcgccacgagcaggag
caggagcagcttctgagcgaggtcttcgaggcctag

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (10)   
   KEGG PATHWAY (8)   
   KEGG MODULE (2)   
Chemical substance (14)   
   KEGG COMPOUND (14)   
Chemical reaction (10)   
   KEGG ENZYME (4)   
   KEGG REACTION (6)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (5)   
   Pfam (5)   
All databases (46)   

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