KEGG   Spirochaeta thermophila DSM 6192: STHERM_c16140Help
Entry
STHERM_c16140     CDS       T01315                                 

Gene name
hemD
Definition
porphyrin biosynthesis protein HemD (EC:2.1.1.107 4.2.1.75)
Orthology
K13542  
uroporphyrinogen III methyltransferase / synthase [EC:2.1.1.107 4.2.1.75]
Organism
sta  Spirochaeta thermophila DSM 6192
Pathway
Porphyrin and chlorophyll metabolism
Metabolic pathways
Biosynthesis of secondary metabolites
Brite
KEGG Orthology (KO) [BR:sta00001]
 Metabolism
  Metabolism of cofactors and vitamins
   00860 Porphyrin and chlorophyll metabolism
    STHERM_c16140 (hemD)
Enzymes [BR:sta01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.107  uroporphyrinogen-III C-methyltransferase
     STHERM_c16140 (hemD)
 4. Lyases
  4.2  Carbon-oxygen lyases
   4.2.1  Hydro-lyases
    4.2.1.75  uroporphyrinogen-III synthase
     STHERM_c16140 (hemD)
BRITE hierarchy
SSDB OrthologParalogGene clusterGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
UniProt: 
Position
complement(1775405..1777423)
Genome map
AA seq 672 aa AA seqDB search
MRVLRLGTRGSRLALAQVREWIARWRDASPEAGEVEWEPMVLHPRGDRDKRTPLHLVEGS
DFFTDALDEALLEGRIDVALHSAKDLPDELREGLSLAAITPLEGPREDVLVLHPRWASAS
SVDELPAGLRIGTSSARRREQLSHLRSDWELVDIRGTIEERLARVSSGEIDGVVMAKVAL
TRLALEVPHLPLPFVPHPLQGRLAAVVREGDEEVRRLCAVLDDRGRWGRVAIVGAGPGTA
DFLTLRAERLLREADLVLYDDLVYPELLAGRTAELVAVGRRKGKERYTVEEVCDLMIQAA
YAGKKVVRLKGGDPSLYARLEEELSWLRAARIPYEVVPGISAFQAASACTEIPLTSREGA
SSLLISTGYPPERALIPPPDGRLSCVYYMAGEEFPRICARFLEAGWDPHTPAVVVSAAAR
PEQTHLSLTLEDGARWTGSLPRPALLLVGATGVSRSWWEDRPHILVTGTRAAPWRARGEV
VHIPCIATVPRRDGRVQEVMEGLSSYTMLIFTSRHGVAHFVDRLLEHGDLRLLAGMRVVA
IGRVTAEALKDRGLVPDLIPEEDSAEGLVSLAAKENWRDEKILIPCSSLSDPFLQEELSR
QGNTVDAVPFYDTVPAPYPEALPLEVGAFDEVVFLSPSGVRVFRERFGALPPGIRIHTPG
ATTRRAVDDATS
NT seq 2019 nt NT seq  +upstreamnt  +downstreamnt
atgcgcgtcttgaggcttggtaccagaggaagcaggctcgccctcgcccaggtgagggag
tggatcgcgcggtggagagacgcctcgcctgaggcgggggaggtggagtgggagcctatg
gtcctccatcccagaggtgatcgcgacaagcgcacccccctccacctcgtagagggctcg
gacttcttcaccgatgccctcgatgaggccctcctggaggggaggatcgacgtggccctc
cacagcgcgaaggacctccccgacgagctccgggaggggctctcccttgcggcgatcacc
cccctcgaggggccgcgcgaggacgtcctcgtgctccacccccgatgggcgtccgcctcc
tctgtggacgagcttccggccggattgcgtatcggcaccagcagtgcgaggaggagggag
cagctctcccacctccggagcgactgggagctcgtggacatacggggcaccatagaggag
cgcctcgcacgcgtctcttccggcgagatagacggggtggtgatggccaaagtggccctc
acccgactggcactggaggtgcctcacctccccctcccctttgtcccccaccccctgcag
ggcagacttgcggcagtggtgcgggagggggacgaggaggtgcgccgcctctgcgcggtc
ctcgacgatcggggccgatggggtagggtggcgatcgtgggtgcagggcccggcactgca
gacttcctcacgctgagggccgaaagactccttcgggaggcggatctcgtcctctacgac
gacctcgtctaccccgagcttctcgcagggaggacggccgagctcgtggcggtggggagg
cggaagggaaaggagcggtacaccgtggaggaggtgtgtgacctgatgatccaggccgcc
tatgcgggaaagaaggtggtccgcctcaagggcggggatccctccctctatgcgaggctc
gaggaagagctctcctggctgagggcggcgaggataccctacgaagtggtgccggggata
agcgcctttcaggccgcctccgcctgcacagagatcccactcacgagcagggagggtgcc
tcctccctcctcatctccacagggtatcctccggagcgggccctcatccccccgccggat
gggcggctttcctgtgtgtactacatggcgggtgaggagttcccccggatatgcgcccgc
ttcctggaggcggggtgggatcctcacacccctgcggtggtggtgagtgcggcggcccgg
cccgaacagacccacctctccctcaccctggaggacggcgcgcggtggaccggatccctc
ccgcgtcccgcgctcctcctggtgggggcgaccggcgtctcccggtcgtggtgggaggac
cgtccccacatcctcgtgaccgggacgcgcgctgccccctggcgggcgcggggggaggtg
gtgcacatcccgtgcatcgccacggtcccccgacgcgatgggagggtccaggaggtgatg
gaaggcctctcctcatacaccatgctcatcttcacctcccgccatggggtggcccacttc
gtggaccgcctcctggagcacggtgatctccgcctccttgcgggcatgcgcgtggtggcc
ataggcagggtcactgccgaggcccttaaggaccgggggctcgttccagacctcatcccg
gaggaggactcggcagaggggctcgtctcgctcgcagcgaaggagaactggagggatgag
aagatcctcatcccctgttcctcgctctcggatccctttttgcaggaggagctttcccgg
caagggaataccgtggatgcggtccccttctacgataccgtccccgccccctatccagag
gcccttccgctggaggtgggcgccttcgacgaggtggtcttcctctcgccctccggcgtg
agggtcttcagggagcgcttcggcgcccttccaccggggatccgcatccataccccagga
gccaccacaaggagggcagtggacgatgctacctcttag

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