KEGG   Thiomicrospira aerophila: THIAE_08530
Entry
THIAE_08530       CDS       T03589                                 
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase
  KO
K01929  UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:6.3.2.10]
Organism
tao  Thiomicrospira aerophila
Pathway
tao00300  Lysine biosynthesis
tao00550  Peptidoglycan biosynthesis
tao01100  Metabolic pathways
tao01502  Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:tao00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00300 Lysine biosynthesis
    THIAE_08530
  09107 Glycan biosynthesis and metabolism
   00550 Peptidoglycan biosynthesis
    THIAE_08530
 09160 Human Diseases
  09175 Drug resistance: antimicrobial
   01502 Vancomycin resistance
    THIAE_08530
Enzymes [BR:tao01000]
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.2  Acid-D-amino-acid ligases (peptide synthases)
    6.3.2.10  UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
     THIAE_08530
SSDB
Motif
Pfam: Mur_ligase_M Mur_ligase_C Mur_ligase
Other DBs
NCBI-ProteinID: AHF01794
UniProt: W0DXT6
Position
complement(1715898..1717355)
AA seq 485 aa
MTTDKGRTVMRFGRWTLGQLAEWLNVILPTKWQAQADLAVAQMVTDSRAVMPGDVYIAIE
GTRFDGHRFIAQAIEQGAVACIISNKNYAKQTVPCLLVSDTTRALGRLGQAHRQAAQLEC
LVAVTGSNGKTTVKELLAALFATKGPTLATQGNLNNQFGVPRTLLRLRDEHRYAVIEMGA
NHQGEIDCLTRLAEPDIAIITLAAPAHLEGFGSLDGIITAKGEIMHGLKPDGVGIINTDS
PGFSHWFGKLTRSGRKAMSFGQAAQADIRIRNVSTTKQGIQFELYYQQAWRTVTSPLLGV
HNAYNLAAGAAVAQVLNWDWDDIAPVFAKFTGTDGRLQIFQLGQLTLIDDSYNANPSSMA
AGLDSLHALASPDNKPMLACLGSMAELGSTAAEAHYQIGRQAVKLGVRQLWAQGGNADDY
VAGFKSLASGKTLAQAAEHAAMIEHLFTLYQTGEPWVVLIKGSRSAAMDQLRPGLTQRIA
DAHLS
NT seq 1458 nt   +upstreamnt  +downstreamnt
atgacaactgacaaagggcggactgtaatgcgatttggacgctggacgctgggacagcta
gcagaatggttaaatgtgattctacccactaaatggcaagcgcaagctgatttagcggtt
gctcagatggtcacggattcacgcgcggtcatgccaggtgatgtctatattgcgattgaa
gggacgcgatttgatggtcatcgatttatcgcccaagcgattgagcagggtgctgtggcc
tgcatcattagcaataaaaactatgctaaacaaactgtgccttgtttattagtgtcggat
accacccgcgcgttgggacggttggggcaggcccaccgacaagccgcacagcttgaatgt
ttagtggcggtgactggttcgaacggtaaaacgaccgttaaagaactgcttgctgctcta
ttcgcgactaaggggccaacacttgcaacacaaggcaatctaaataatcaatttggtgtg
ccacgcacattattacgtttgcgtgatgagcaccggtatgcagtgattgaaatgggcgcg
aaccatcaaggcgaaattgattgtttaacccgcttagctgaaccggatattgcgattatt
acccttgctgccccggctcatcttgaaggttttggcagtcttgatggcattattaccgct
aaaggcgaaattatgcatggcttaaagcctgatggcgttggcatcattaatactgattcg
cccggttttagccactggtttggtaaattgacccgaagtggtcgtaaagcgatgagtttt
ggccaggctgcacaagctgacattcggattcgaaatgtgtccaccaccaagcaaggcatt
cagtttgagctgtattatcagcaggcctggcgcaccgtcactagcccgttactaggggtt
cacaacgcctacaatcttgcggcaggcgcagcggtggcacaggtgttaaattgggattgg
gatgacattgcaccggtgtttgccaagtttacgggtacagatggtcggttgcagattttt
cagctgggtcaactcaccttaattgatgatagttacaacgctaatccaagctcgatggcg
gcagggttagatagtctacatgcgcttgccagtccggataacaagccgatgctggcctgc
ttaggatctatggcagagttaggcagtaccgctgctgaggcccattatcaaattggtcgg
caggcggttaaattaggtgtgcgccaactctgggcacagggtggcaatgccgacgattat
gtcgcgggctttaagtcgttagcaagcggtaaaaccttggcccaagccgccgaacacgcg
gcgatgattgaacacttatttaccctttatcaaactggcgaaccctgggtcgtcttaatt
aaaggctcgcgcagtgccgcaatggatcagttgcgccctggcctaactcaaaggattgcc
gatgctcatttatcttag

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (4)   
   KEGG PATHWAY (4)   
Chemical substance (8)   
   KEGG COMPOUND (8)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (3)   
   Pfam (3)   
All databases (25)   

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