KEGG T01012: 510105.170

Trypanosoma cruzi: 510105.170

Entry

510105.170 CDS T01012

Definition

dihydrolipoamide acetyltransferase precursor (EC:2.3.1.12)

Orthology

K00627

pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase) [EC:2.3.1.12]

Organism

tcr Trypanosoma cruzi

Pathway

tcr00010	Glycolysis / Gluconeogenesis
tcr00020	Citrate cycle (TCA cycle)
tcr00620	Pyruvate metabolism
tcr01100	Metabolic pathways
tcr01110	Biosynthesis of secondary metabolites

Module

tcr_M00307

Pyruvate oxidation, pyruvate => acetyl-CoA

Class

Metabolism; Carbohydrate metabolism; Glycolysis / Gluconeogenesis [PATH:tcr00010]
Metabolism; Carbohydrate metabolism; Citrate cycle (TCA cycle) [PATH:tcr00020]
Metabolism; Carbohydrate metabolism; Pyruvate metabolism [PATH:tcr00620]

SSDB

Motif

Pfam:

2-oxoacid_dh Biotin_lipoyl E3_binding PA_decarbox DUF3614

Other DBs

NCBI-GI:

71665855

NCBI-GeneID:

3552402

GeneDB:

Tc00.1047053510105.170

UniProt:

Q4DZT8

AA seq 471 aa
MFRRRVVQQLSSAVASLRLLTITPIPMPALSPTMEKGKISEWVTKVGDSVASGDTWCKVE
TDKAVVSYDNVSEEGFVARILVQTGEEASVGDTVCLIVDEADGINSDEVKNWHAEGAAPS
RAEEPSAAAASPSTGPAAPIPTSPSTSGGRVKASPLARKTAQELNVSLEGIIGTGGGVGR
IVKKDVEAAAASGSARSSAAAEAAQTKVQSIPKQMPAPDVATVAATSKLTPAVNENYTDI
PVSNMRATIARRLTQSKNVDIPHYYLFEECCADNMLALIKQLNAKGDGKYKITVNDYTIK
AVARANILVPEANSSWQGDVIRQYNTVDVSVAVATPTGLITPIVKNAQARGLADISTEMK
ELAKKARDGKLQPHEFIGGTVSISNLGASGIPGFTAIINPPQSLILAVGSAKPRPKISFN
EETGKYQVGTEVEMVIKFTASFDHRVVDGAVGAEWCKHFKDAIENPLSLLL

NT seq 1416 nt +upstreamnt +downstreamnt
atgtttcgccgacgtgtggttcagcagctcagcagcgccgtggcttctcttcggctcctg
actattacgcctatcccgatgccggcactctcccctacaatggagaagggaaagatctcg
gagtgggtcacgaaggtcggcgattccgttgcctctggtgatacatggtgcaaggttgag
acggacaaggctgtcgtgtcatacgacaacgtgtcagaggagggatttgttgcccgtatt
cttgtccagactggcgaggaggcctccgttggtgacacggtttgtcttatcgttgacgag
gcagacggcatcaactcggacgaggtgaagaactggcatgcagagggtgctgccccatca
cgggcagaggaaccatctgcagctgccgcgtccccttcgactggtcccgccgcgccaatc
cccacatcaccttccacgagcggtggccgcgtaaaggcatccccgcttgcccgcaagacg
gcgcaggagctcaacgtgtcgctggagggcatcattggcaccggcggtggcgttggtcgt
atcgttaagaaagacgtggaggcggcggcagctagcggcagcgcgaggtcatcggccgcg
gcagaagcggcccaaaccaaagtccaatccattcccaagcaaatgccggcaccagacgta
gcaacagtagcggcaacatcgaagctcacaccagcggtgaacgagaactacacggatatt
cccgtttccaacatgcgtgcgacaatcgcaaggcgtctaacgcagtccaagaatgtggat
attccacactactacctatttgaggagtgttgtgctgacaacatgctagcactcattaag
cagttgaacgccaagggtgatggcaagtacaagatcaccgtgaatgactacaccattaag
gcggtggcgagggcgaacattttggtaccggaggccaattcctcttggcagggggatgtg
atacgccagtacaacacggttgatgtaagcgtggcggttgcaaccccaacaggtcttatt
actcccatcgtcaagaatgctcaagcaaggggactggcggatatctcgacagaaatgaaa
gaacttgcaaagaaggcgcgtgacggtaagttgcagccacatgaattcattggcggtacg
gtgtccatctccaacttgggtgcctccggcatccccggattcacggccatcattaacccc
ccgcagtcactcattcttgccgttggctctgcaaagccgcggccaaagatatcatttaac
gaggagacgggcaagtaccaggtaggcacggaggtggaaatggtcatcaagttcacggcg
tccttcgaccaccgcgttgtcgacggcgcagttggcgcggagtggtgcaagcattttaag
gatgctatcgagaacccactttcactgttgctctaa

All links

Pathway (6)   
   KEGG PATHWAY (5)   
   KEGG MODULE (1)   
Chemical substance (4)   
   KEGG COMPOUND (4)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (5)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (1)   
   GENEDB (1)   
   OC (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (5)   
   Pfam (5)   
All databases (26)   

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