| Entry |
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| Definition |
Uroporphyrinogen III synthase HEM4
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| Orthology |
| uroporphyrinogen-III synthase [EC: 4.2.1.75] |
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| Organism |
tcu Thermomonospora curvata
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| Pathway |
| Porphyrin and chlorophyll metabolism | | Metabolic pathways | | Biosynthesis of secondary metabolites |
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| Module |
| Heme biosynthesis, glutamate => protoheme/siroheme |
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| Brite |
KEGG Orthology (KO) [BR:tcu00001]
Metabolism
Metabolism of cofactors and vitamins
00860 Porphyrin and chlorophyll metabolism
Tcur_2410
Enzymes [BR:tcu01000]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
Tcur_2410
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| SSDB |
    |
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| Motif |
 |
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| Other DBs |
NCBI-GI: NCBI-GeneID: UniProt: |
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| Position |
complement(2804090..2805262)
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| AA seq |
390 aa  
MNTDHEPLAGFAVGVTAARRHEELAALLERRGARVVHAPAIRLVPLADDAELLHATNVCI
ADRLDYVVVTTAIGFRAWLETADGWGLRDALIERLHKARILARGPKARGAIRSAGLQEEW
SPDSESCQELLRHLLAEDLTGTRIAVQLYGEPLPDFTGALRAAGAEVIEVPVYRWSRTDD
STPLRRLVGQAVAGTIDAITFTSAPAVTATLAVAAEDGLEEALLEALRTHTVAACVGPVT
AQPLTDRGVPTVQPERARIGALVRALAADLPRRRARRINVRGHTLELRGHAVVLDGQLRP
IAPAPMAILRALARRPGHVVSRAELCTVLPSRVITGSGWGRDGRPQADEHAVEMAVARLR
RGLGRSGIVETVVKRGYRLACDPVRTDRPF |
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| NT seq |
1173 nt  +upstreamnt +downstreamnt
atgaacactgaccatgaaccgctcgccgggttcgcggtcggggtgaccgcggcacggcgg
cacgaggagttggccgcgctgctggaacggcgcggggcacgggtggtgcacgcccccgcg
atccggctggtgccgctggccgacgacgccgaactgctgcacgccaccaacgtgtgcatc
gccgacaggctcgactatgtcgtcgtcaccaccgccatcggtttccgcgcctggctggag
acggccgacggctgggggctgcgcgacgccttgatcgagcggctgcacaaggcccgcatc
ctggcccgcggccccaaggcccgcggcgccatccgctcggcgggcctgcaggaggagtgg
tcgccggattcggaaagctgccaggagctgctgcgtcacctgctggccgaggacctgacc
ggcacccgcatcgcggtgcagctgtatggggagccgctgccggacttcaccggcgcgctg
cgcgccgccggcgccgaggtgatcgaggtgccggtctaccgctggtcgcgcaccgacgac
tccacgccgctgcgccggctggtggggcaggccgtggccggcaccatcgacgccatcacc
ttcaccagcgcccccgccgtcaccgccacgctggcggtggcggccgaggacggcctggag
gaggcgttgctggaggcgctgcgcacccacacggtggccgcctgcgtcggcccggtcacc
gcccagccgctgaccgaccgcggcgtacccaccgtccagcccgagcgggccaggatcggg
gcgctggtgcgggcgctggccgccgacctgccgcggcggcgggcccggcggatcaacgtc
cgcggccacaccctggagctgcgcgggcacgccgtcgtgctggacgggcagctgcggccg
atcgccccggcgccgatggcgatcctgcgggcgctggcccgccggcccggccatgtggtc
tcccgggccgagctgtgcacggtgctgcccagccgggtgatcaccggaagcggctggggc
cgggacggccgcccgcaggccgatgagcacgcggtggagatggcggtggcccggctgcgg
cgcggcctgggccgctcgggcatcgtggagaccgtggtcaaacgcggctaccggctggcc
tgcgacccggtacgcaccgatcgtcccttttga |
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