KEGG T00296: Tcr

Thiomicrospira crunogena: Tcr_1878

Entry

Tcr_1878 CDS T00296

Definition

2-isopropylmalate synthase (EC:2.3.3.13)

Orthology

K01649

2-isopropylmalate synthase [EC:2.3.3.13]

Organism

tcx Thiomicrospira crunogena

Pathway

tcx00290	Valine, leucine and isoleucine biosynthesis
tcx00620	Pyruvate metabolism
tcx01100	Metabolic pathways
tcx01110	Biosynthesis of secondary metabolites
tcx01210	2-Oxocarboxylic acid metabolism
tcx01230	Biosynthesis of amino acids

Module

tcx_M00432

Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate

Class

Metabolism; Carbohydrate metabolism; Pyruvate metabolism [PATH:tcx00620]
Metabolism; Amino acid metabolism; Valine, leucine and isoleucine biosynthesis [PATH:tcx00290]

SSDB

Motif

Pfam:

HMGL-like LeuA_dimer

Other DBs

NCBI-GI:

NCBI-GeneID:

JGI:

UniProt:

Position

2053565..2055184

AA seq 539 aa
MTPEKYRPTITPDLPNRQWPNQRLTQAPIWASVDLRDGNQALANPMTVEQKLKLWDQLVA
IGFKTIEIGFPAASQLEFDFARRLIEENRIPDDVTVQVLVQAREHLIKRTYEALQGVKQA
VVHVYNTTSTVQREKVFCKSKADIKAMAIQGAKWVQSYAKEHPESDWVFQYSPESFSQTE
TDYAVEVCQAVMDVWQPTPDNRCILNLPATVESTSPNRFADQVEYFITHLKNRESAIISI
HTHNDRGCAVAAAELSLLAGADRVEGTLLGNGERTGNMDIVTLAMNLYSEGIDPELNLSD
PDSWVPVIEEVTKIDTHVRHPWVGEAVYTAYSGSHQDAIRKCLMRQKDDEPWNVAYLPID
PKDLNRSYEAIIRVNSQSGKAGAAFVLTQEYDLNLPKWVQQDFAPVAQTIAEQAGGIVSH
QMLYDAFIQHYRLDKSLAELNNYQLSRKEGKEHLSVEVNGETWQGQGNGTLSALCDAWQR
RTGQQVDVLDYSEHALHEGKDSKAIAYVYVQQKNTKTIGIAMAEDTVSAMIQALLSTIR

NT seq 1620 nt +upstreamnt +downstreamnt
atgactcctgaaaaatatcgcccaacgatcacgcccgatttacccaatcgccagtggccg
aaccaacgccttacccaggcaccgatttgggcaagtgtcgatctacgagacggcaatcag
gcgttagccaacccaatgacggtggagcagaagcttaagctttgggatcaactggtggcg
attggttttaaaaccatcgaaatcggtttcccggccgccagtcagttggagtttgatttt
gcgcgccgcttaattgaagaaaaccgcattccggacgatgtgacggtgcaggtgctggtg
caggccagagagcatttgattaagcgcacttatgaagcgttgcaaggcgtgaagcaagcg
gtggtgcatgtgtacaacaccacctctaccgtacaacgtgaaaaggttttctgtaaatcg
aaagccgacattaaagccatggcaatccaaggcgccaaatgggtacaaagctatgctaaa
gaacacccggaatccgactgggtattccagtattcaccagaaagcttttctcaaaccgag
accgattatgcggtggaagtgtgtcaggcggtgatggatgtgtggcaaccgacaccagac
aatcgttgcattttaaacttgccggccacggtggaaagcacgtctccaaaccgttttgcc
gaccaagtggaatatttcattacccatttgaaaaaccgtgagtcggccattatttccatc
catacccataacgatcgcggctgtgccgttgcggcggcggaactgtcattactggcgggc
gcggatcgcgtggaaggcactttgttaggcaatggcgagcgcaccggaaacatggacatc
gtcaccttggcgatgaacctttacagcgaaggcattgaccctgaattaaacctatccgac
ccagacagctgggtgccggtgattgaagaagtgacgaaaatcgacacccatgttcgccat
ccttgggtgggtgaagcggtttacacagcgtattccggcagtcatcaggatgcgattcgt
aaatgtttgatgcgccagaaagacgatgaaccgtggaatgtagcgtatttaccgattgat
ccgaaagatttgaatcgaagttatgaagcgattattcgtgtcaacagccagtccggaaaa
gcgggtgcggcattcgtgctgacacaggaatatgatttgaacttaccgaaatgggtgcag
caagattttgcgcctgttgcacaaaccattgccgaacaagccggtggcattgtcagccac
cagatgctgtatgatgcctttattcaacattatcgtttggataagtctttagcggaattg
aacaattaccaattgtcacgcaaggaaggcaaagagcatttaagtgtggaagtgaacggt
gaaacctggcaaggccaaggcaacggcaccttaagcgcactgtgtgatgcgtggcaacga
cgcaccggacagcaagtggatgtgttggattacagcgaacacgccttgcatgaagggaaa
gactcaaaagcgattgcctatgtctatgtgcagcagaaaaacaccaaaaccatcggtatc
gccatggcggaagatacggtttctgcgatgattcaggccttactctcgaccattcgttaa

All links

Pathway (7)   
   KEGG PATHWAY (6)   
   KEGG MODULE (1)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (5)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (1)   
   JGI-TCX (1)   
   OC (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
Protein domain (2)   
   Pfam (2)   
All databases (24)   

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