KEGG   Thermus sp. CCB_US3_UF1: TCCBUS3UF1_9320
Entry
TCCBUS3UF1_9320   CDS       T01866                                 
Name
(GenBank) 2-isopropylmalate synthase
  KO
K01649  2-isopropylmalate synthase [EC:2.3.3.13]
Organism
thc  Thermus sp. CCB_US3_UF1
Pathway
thc00290  Valine, leucine and isoleucine biosynthesis
thc00620  Pyruvate metabolism
thc01100  Metabolic pathways
thc01110  Biosynthesis of secondary metabolites
thc01210  2-Oxocarboxylic acid metabolism
thc01230  Biosynthesis of amino acids
Module
thc_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:thc00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00620 Pyruvate metabolism
    TCCBUS3UF1_9320
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    TCCBUS3UF1_9320
Enzymes [BR:thc01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.3  Acyl groups converted into alkyl groups on transfer
    2.3.3.13  2-isopropylmalate synthase
     TCCBUS3UF1_9320
SSDB
Motif
Pfam: HMGL-like LeuA_dimer Guanylate_kin TipAS
Other DBs
NCBI-ProteinID: AEV15977
UniProt: G8NC87
Position
917914..919470
AA seq 518 aa
MERHIRIFDTTLRDGEQSPGVALSLDQKLEIAHALARLNVDIIEAGFPVSGPLEFEAVRR
IAAEVKGPVIAALARTHTLDIDQAAKALEKAEKPRIHVFTSASKIHLEHMLKKTEEEVLE
MADQMVRYARRYVDDVEFSAQDVMRAEWDFVKRLYEVAIEAGATTINIPDTTGYGTPLEY
GALIRRIRDEVVRGRDVIISTHTHDDLGLATANALAGIENGAGQVECTINGIGERAGNTS
LEEVVMALYVRRDWYKAYTRINTREIYRVSRLVERYTGMPVPPNKAIVGDNAFAHESGIH
QDGVLKHRSTYEIMDAELIGRRPAVIVLGKHSGRAAFKKALEDLGYKDLSEEELKKLFAR
FKEIAEKKGPLSAEELQALVESEREPASHFFTLEHVQFFSGSGLLPTATVKVKTPEGERL
ATHTGDGPVDAVYKALEEAIGLRPELELYRVEAITGSTEALGQVTVRLRLGELQAVGVGV
SPDIIEASALAFLDAAGKLASGRATRHPPSIAEVQRGV
NT seq 1557 nt   +upstreamnt  +downstreamnt
atggagcggcacatccggatcttcgataccaccttgcgggatggcgagcagagccctggg
gtagcgctttccctggaccagaagctggagatcgcccacgccctggcccggctcaacgtg
gacatcattgaggcgggcttccccgtatccgggcccttggagtttgaggccgtgcgccgc
atcgccgccgaggtcaagggcccggttatcgccgctttggcccgcacccacaccttggac
attgaccaggcggccaaggccttggaaaaggcggaaaagccccggatccacgtcttcacc
tcggcctccaagatccacctggagcacatgctgaagaagacggaggaggaggttttggag
atggcggaccagatggtccgctacgcccgccgctacgtggacgacgtggagttttccgcc
caggacgtgatgcgggccgagtgggacttcgtgaagcgcctctatgaggtggccattgag
gccggggccaccaccatcaacatccccgacaccaccggctacggcactcccctggagtac
ggggccctgatccgccgcatccgggacgaggtggtccgggggcgggacgtgatcatctcc
acccacacccacgacgacctgggcctggccacggccaacgccctggcggggattgaaaac
ggggccggccaggtggagtgcaccatcaacggcatcggggagcgggcggggaacacctcc
ttggaggaggtggtcatggccctctacgtgcgccgggactggtacaaggcctacacccgg
atcaacacccgggagatctaccgggtttcccgcctggtggagcggtacaccggcatgccc
gtcccccccaacaaggccatcgtgggggacaacgccttcgcccacgagtccggcatccac
caggatggggtgctgaagcaccgctccacctacgagatcatggacgcggagctcatcggc
aggcggccagcggtgatcgttctcggcaagcactctggccgggcggccttcaagaaggcc
ctcgaggacctgggctacaaggacctttccgaggaggagctgaagaagcttttcgcccgc
ttcaaggagatcgccgagaagaagggccccctctccgccgaggagctccaggccctggtg
gaaagcgagcgggagcccgcctcccacttctttaccctggaacatgtccagtttttctcc
ggatccggcctcctgcccacggccacggtgaaggtgaagaccccggagggggagaggttg
gccacccataccggggatggcccggtggatgccgtgtacaaggccctggaggaggccatc
ggccttaggcccgagctggagctttaccgggtggaggccatcacggggagcaccgaggcc
ctgggccaggtgaccgtgcgcctgcggctgggggagctccaggccgtgggcgtgggggtt
tccccggacatcattgaggccagcgccctggccttcctggatgccgctggcaagctggct
tcgggacgggccaccaggcacccgccttccatcgcggaggtgcagcggggtgtctaa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (7)   
   KEGG PATHWAY (6)   
   KEGG MODULE (1)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (4)   
   Pfam (4)   
All databases (25)   

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