KEGG   Thermotoga maritima MSB8: TM0554
Entry
TM0554            CDS       T00022                                 
Name
(GenBank) 3-isopropylmalate dehydratase, large subunit
  KO
K01703  3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:4.2.1.33 4.2.1.35]
Organism
tma  Thermotoga maritima MSB8
Pathway
tma00290  Valine, leucine and isoleucine biosynthesis
tma00660  C5-Branched dibasic acid metabolism
tma01100  Metabolic pathways
tma01110  Biosynthesis of secondary metabolites
tma01210  2-Oxocarboxylic acid metabolism
tma01230  Biosynthesis of amino acids
Module
tma_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:tma00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00660 C5-Branched dibasic acid metabolism
    TM0554
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    TM0554
Enzymes [BR:tma01000]
 4. Lyases
  4.2  Carbon-oxygen lyases
   4.2.1  Hydro-lyases
    4.2.1.33  3-isopropylmalate dehydratase
     TM0554
    4.2.1.35  (R)-2-methylmalate dehydratase
     TM0554
SSDB
Motif
Pfam: Aconitase AcnX
Other DBs
NCBI-ProteinID: AAD35639
UniProt: Q9WZ24
Position
582681..583934
AA seq 417 aa
MTLAEKILSQKAGRKVEPGEFLLLEPDIALANDITAPLAIKKFKEYGGKKVKYPDRVVLV
PDHFTPNKDIKSAMQVKMMREFAREQGIEKFFEIGRMGIEHVLLPEEGIVKSGDLVVGAD
SHTCTYGALGAFATGVGSTDIAGFYLIGKVWFRVPESIKVTLRGKFKDLVTAKDLVLKLI
SILGVDGANYKAIEFSGPGVKEISMDGRFTISNMAIEAGGKTGLFPVDEITIAYERERGI
EVEEMYPDEDAKYVREVEMDLSELEPQVAYPFLPSNAKDVSEAEKERIKIDQAVIGSCTN
GRIEDLRLAAQILKGRTVSPDVRCIIIPGSQKVYKQALKEGLIDIFIDAGCAVSTPTCGP
CLGGHMGVLAEGEVAISTTNRNFVGRMGHPNSKVFLASPAVAAASAIKGYIADPRKL
NT seq 1254 nt   +upstreamnt  +downstreamnt
atgacactcgcagaaaagatactctctcaaaaagcgggaagaaaggtggaaccgggagaa
tttctccttctggagccggacatcgctctcgcgaacgacataacggctccgcttgcgata
aagaagttcaaggagtacggtggaaagaaagtgaagtatccagacagagtggtgctcgtt
ccagaccatttcacccccaacaaggacataaagtccgccatgcaggtgaagatgatgaga
gaatttgccagagagcaggggatcgaaaagttcttcgaaataggcaggatgggtattgaa
cacgtgctgcttccagaagaaggaatcgtgaaatccggagatctcgtggtcggtgcggat
tcacacacctgtacctacggagcccttggagcgtttgcgaccggagtggggtccaccgac
atcgcgggcttctatctcataggaaaggtatggttccgtgtccccgagagtataaaggtg
actcttcgcgggaagttcaaggatctggtgactgccaaagacctcgtgttgaagctcatc
tcgatactcggtgtagatggagccaactacaaggcgatagaattctctggaccgggtgtg
aaagagatcagcatggacggccgttttaccatttcgaacatggcgatcgaggcgggagga
aagacgggactgtttccggtggacgagatcaccattgcctacgaaagagaaagaggcata
gaagtggaagagatgtacccggacgaagacgcaaaatacgtgagagaagtggaaatggac
ctttctgagctcgaacctcaggttgcatatcccttcctcccatccaacgcgaaggacgtt
tccgaagctgagaaagagagaataaagatagatcaggcggtgataggaagctgtaccaac
ggaaggatagaagatctcagacttgccgcgcagattctgaagggaaggacagtatcaccg
gacgttcgatgcatcataattccgggatcccagaaggtttacaaacaggctctcaaagaa
ggactcatcgacatattcatcgacgcgggctgcgccgtttccacgcccacatgtggaccc
tgtcttggcggacacatgggagtgctcgcagaaggagaggttgcgatctccacaacgaac
aggaacttcgttggaaggatgggacatccgaacagcaaggttttcctggcatctcctgca
gtggcggcggccagcgcaataaaaggatacatcgcagatccgagaaagctgtga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (8)   
   KEGG PATHWAY (6)   
   KEGG MODULE (2)   
Chemical substance (19)   
   KEGG COMPOUND (19)   
Chemical reaction (13)   
   KEGG ENZYME (2)   
   KEGG REACTION (11)   
Genome (1)   
   KEGG GENOME (1)   
Gene (10)   
   KEGG ORTHOLOGY (1)   
   RefGene (7)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (2)   
   UniProt (1)   
   SWISS-PROT (1)   
Protein domain (2)   
   Pfam (2)   
All databases (57)   

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