KEGG   Thermotoga maritima MSB8: THEMA_01915
Entry
THEMA_01915       CDS       T02976                                 
Name
(GenBank) alpha-isopropylmalate/homocitrate synthase family transferase
  KO
K01649  2-isopropylmalate synthase [EC:2.3.3.13]
Organism
tmi  Thermotoga maritima MSB8
Pathway
tmi00290  Valine, leucine and isoleucine biosynthesis
tmi00620  Pyruvate metabolism
tmi01100  Metabolic pathways
tmi01110  Biosynthesis of secondary metabolites
tmi01210  2-Oxocarboxylic acid metabolism
tmi01230  Biosynthesis of amino acids
Module
tmi_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:tmi00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00620 Pyruvate metabolism
    THEMA_01915
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    THEMA_01915
Enzymes [BR:tmi01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.3  Acyl groups converted into alkyl groups on transfer
    2.3.3.13  2-isopropylmalate synthase
     THEMA_01915
SSDB
Motif
Pfam: HMGL-like LeuA_dimer SpoIISA_toxin
Other DBs
NCBI-ProteinID: AHD17692
Position
complement(364464..366080)
AA seq 538 aa
MSIKVYDTTLRDGAQAFGVSFSLEDKIRIAEALDDLGVHYLEGGWPGSNPKDIAFFEAVK
GMNFKNLKVAAFSSTRRPDVKIEEDANIQTLIKAETPVYTIFGKSWDLHVEKALRTTLEE
NLKMIYDTVSYLKRFADEVIYDAEHFFDGYKANREYALKTLKVAEEAGADCLVLADTNGG
TLPHEIEEIIEDVKKHVKAPLGIHAHNDSDVAVANTLAAVRKGAVHVQGTINGLGERCGN
ANLCSVIPNLVLKMGLEVIPKENLKKLFDVAHLVAELSGRPHIENMPYVGDYAFAHKGGV
HVSAIKRDPRTYEHIDPELVGNRRIISISELSGKSNVLEKIKEMGFEIDESSPKVREILK
KIKELEAQGYHFEGAEASFELLVRDMLGKRKKYFEFLGFTVMTIKNRDEESFSEATVKVR
VPDEVAKRLGHDEPFEHTAAEGEGPVEALDRAVRKALEKFYPSLKDTKLTDYKVRILNEQ
AGTKATTRVLIESSDGKRRWGTVGVSPNIIEASWTALLESLEYKLHKDEEEMRNDEEN
NT seq 1617 nt   +upstreamnt  +downstreamnt
ttgagtataaaggtctacgatacaacgctcagggacggtgcgcaggcctttggagtttct
ttctcactcgaagataagatcagaattgccgaggcactcgatgacctcggtgttcactat
cttgaagggggttggcctggctccaacccgaaggatatagcgttttttgaagctgtaaaa
ggtatgaacttcaagaatctgaaagtggcggccttcagttccacaagaaggcccgacgta
aaaatagaagaagacgcgaacattcagaccctcataaaagcggaaacacctgtttacacg
atctttggaaagagctgggatcttcacgtggaaaaagccttgcgaacgacactcgaagag
aatctgaagatgatatacgacacagtttcatatctcaaaagattcgccgatgaggtgata
tacgacgcggaacacttcttcgatgggtacaaggcgaacagagagtacgccctcaaaact
ctgaaggtggctgaagaagcgggggctgattgtctcgttctcgctgacacgaacggtgga
acgcttccacacgagatcgaggagatcatcgaggatgtgaaaaagcacgtgaaagctccg
ctcggaatacacgctcacaacgattcggatgtggcggtggcgaatacactcgcggctgtg
agaaagggagccgtgcacgtccaggggaccataaacggccttggagagagatgtggaaac
gcgaatctctgttcggtgattccgaatctcgtcctcaagatgggtcttgaggttatacca
aaggaaaatctgaagaaactcttcgatgtggcacacctcgttgcagaactctccggaaga
ccccacatcgagaacatgccctatgtgggtgattacgccttcgctcacaagggaggagtc
catgtttctgccataaaacgcgatccaaggacttacgaacacatcgacccggaactcgtg
gggaacagaaggatcatatccatctcggaactttccggtaagagcaacgtgctggagaag
ataaaggaaatgggattcgaaatagatgagtcatcgcccaaggtcagggagatcctcaaa
aagatcaaggaattggaagcgcaggggtaccacttcgagggtgcggaggcatctttcgag
cttctcgtcagggatatgctcgggaaaagaaagaagtactttgagtttctcggtttcacc
gtgatgaccataaagaacagggatgaggagagtttctccgaagcaaccgtgaaggtcaga
gtcccggacgaagttgcgaagagactgggacacgacgaaccctttgaacacacagcagcg
gaaggagaaggaccggtagaagccctcgacagagcggtgagaaaagccctcgagaaattc
tatccatctttgaaagacacgaaactcacggactacaaggtgagaatcctgaacgagcag
gcgggcaccaaagcgacaacacgggttctcatagagtccagcgacggaaagagaaggtgg
ggaactgtgggcgtctcaccgaacatcatagaggcttcctggaccgctcttctcgaatcc
ttagagtacaagcttcacaaggatgaagaggagatgagaaacgatgaggagaattaa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (7)   
   KEGG PATHWAY (6)   
   KEGG MODULE (1)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein domain (3)   
   Pfam (3)   
All databases (23)   

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