KEGG   Trichechus manatus latirostris (Florida manatee): 101355711
Entry
101355711         CDS       T05135                                 
Name
(RefSeq) dual specificity mitogen-activated protein kinase kinase 3
  KO
K04432  mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
Organism
tmu  Trichechus manatus latirostris (Florida manatee)
Pathway
tmu04010  MAPK signaling pathway
tmu04015  Rap1 signaling pathway
tmu04218  Cellular senescence
tmu04620  Toll-like receptor signaling pathway
tmu04664  Fc epsilon RI signaling pathway
tmu04668  TNF signaling pathway
tmu04714  Thermogenesis
tmu04750  Inflammatory mediator regulation of TRP channels
tmu04912  GnRH signaling pathway
tmu04935  Growth hormone synthesis, secretion and action
tmu04936  Alcoholic liver disease
tmu05014  Amyotrophic lateral sclerosis
tmu05022  Pathways of neurodegeneration - multiple diseases
tmu05132  Salmonella infection
tmu05135  Yersinia infection
tmu05145  Toxoplasmosis
tmu05161  Hepatitis B
tmu05169  Epstein-Barr virus infection
tmu05170  Human immunodeficiency virus 1 infection
tmu05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
tmu05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:tmu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    101355711
   04015 Rap1 signaling pathway
    101355711
   04668 TNF signaling pathway
    101355711
 09140 Cellular Processes
  09143 Cell growth and death
   04218 Cellular senescence
    101355711
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    101355711
   04664 Fc epsilon RI signaling pathway
    101355711
  09152 Endocrine system
   04912 GnRH signaling pathway
    101355711
   04935 Growth hormone synthesis, secretion and action
    101355711
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    101355711
  09159 Environmental adaptation
   04714 Thermogenesis
    101355711
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    101355711
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    101355711
   05161 Hepatitis B
    101355711
   05169 Epstein-Barr virus infection
    101355711
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    101355711
   05135 Yersinia infection
    101355711
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    101355711
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    101355711
   05022 Pathways of neurodegeneration - multiple diseases
    101355711
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    101355711
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    101355711
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:tmu01001]
    101355711
Enzymes [BR:tmu01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     101355711
Protein kinases [BR:tmu01001]
 Serine/threonine kinases: STE group
  STE7 family
   101355711
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like ABC1 Haspin_kinase Seadorna_VP7 Pkinase_fungal APH Choline_kinase RIO1 DUF4344
Other DBs
NCBI-GeneID: 101355711
NCBI-ProteinID: XP_004381080
UniProt: A0A2Y9DU11
Position
Unknown
AA seq 347 aa
MESPASSQPPSAPPSKGKSRKKKDLRITCVCKPPPPNPTPPRNLDSRTFITIGDRNFEVE
ADDLVTISELGRGAYGVVEKVRHAQSGTIMAVKRIRATVNSQEQKRLLMDLDINMRTVDC
FYTVTFYGALFREGDVWICMELMDTSLDKFYRKVLDKNMTIPEDILGEIAVSIVRALEHL
HSKLSVIHRDVKPSNVLINKEGHVKMCDFGISGYLVDSVAKTMDAGCKPYMAPERINPEL
NQKGYNVKSDVWSLGITMIEMAILRFPYESWGTPFQQLKQVVEEPSPQLPADRFSPEFVD
FTAQCLRKNPTERMSYLELMEHPFFTLHKTKKTDIAAFVKEILGEDS
NT seq 1044 nt   +upstreamnt  +downstreamnt
atggagtcgcccgcctcgagccagcctcctagcgcacccccgtccaaaggaaaatccagg
aagaagaaggatttacggataacctgcgtgtgtaagcctccaccacccaaccccacaccc
ccccggaaccttgattcccggaccttcatcaccataggagacaggaacttcgaggtggaa
gccgatgacctcgtgaccatctcggagttgggccgtggagcctatggggtagtggagaag
gtgcgacatgcccagagtggcaccatcatggctgtgaagcggatccgagccaccgtgaac
tcacaggagcagaagaggctgctcatggacttggacatcaacatgcggacagttgactgc
ttctacactgtcaccttctacggggccctcttcagagagggtgatgtgtggatctgtatg
gagctcatggacacctctctggataagttctaccggaaggtgctggataaaaacatgaca
attccagaggacattttgggggagattgctgtgtcgatcgtgagggctctggagcacctg
cacagcaagctctccgtgatccacagagacgtgaagccctctaatgtactcatcaacaag
gagggccacgtgaagatgtgtgactttgggattagtggctacttggtggactccgtggcc
aagactatggacgccggctgcaagccctacatggcccccgagagaatcaacccagagctg
aaccagaagggctacaatgtcaagtccgatgtctggagcctcggcatcacaatgattgag
atggccatcctgcggttcccttatgagtcctgggggaccccattccagcagctgaagcag
gtggtagaggagccatccccccagctcccggctgaccggttctcccctgagtttgtagac
ttcactgcacagtgcctgaggaagaaccccacggagcgcatgagctacctggagctgatg
gagcaccctttcttcaccttgcacaaaaccaagaagacggacattgctgccttcgtgaag
gagatcctgggggaggactcgtag

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (21)   
   KEGG PATHWAY (21)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   RefGene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (11)   
   Pfam (11)   
All databases (46)   

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