KEGG T04728: A0127

Thermococcus peptonophilus: A0127_02265

Entry

A0127_02265       CDS       T04728

Name

(GenBank) phosphomethylpyrimidine kinase

K21219

hydroxymethylpyrimidine kinase / phosphomethylpyrimidine kinase / thiamine-phosphate diphosphorylase [EC:2.7.1.49 2.7.4.7 2.5.1.3]

Organism

tpep Thermococcus peptonophilus

Pathway

tpep00730

Thiamine metabolism

tpep01100

Metabolic pathways

tpep01240

Biosynthesis of cofactors

Module

tpep_M00896

Thiamine biosynthesis, archaea, AIR (+ NAD+) => TMP/TPP

Brite

KEGG Orthology (KO) [BR:tpep00001]
09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00730 Thiamine metabolism
    A0127_02265
Enzymes [BR:tpep01000]
2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.3  thiamine phosphate synthase
     A0127_02265
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.49  hydroxymethylpyrimidine kinase
     A0127_02265
   2.7.4  Phosphotransferases with a phosphate group as acceptor
    2.7.4.7  phosphooxymethylpyrimidine kinase
     A0127_02265

SSDB

Motif

Pfam:

Phos_pyr_kin ThiP_synth PfkB Carb_kinase

Other DBs

NCBI-ProteinID:

AMQ18077

UniProt:

A0A142CTH5

Position

437451..438749

AA seq 432 aa
MAVLIIAGLDTGGGAGLKADIETVSALGEHPLPVVSAITYQNPDEVRGVFPVPPNTIREQ
IRAVKGVFEIRAVKIGLLHGGAVKVIAEETKGLIRVLDPVIASSSGFRFLSPEDVEILKR
ELLPGSIVTPNVPEAEVLTGLKINSIEDIKRVARVLVEELGAEAAIVKGGHLNFTDVLYW
NGEVFKFSGERVEGFTHGTGCVFSSALAAFIAKGLELPKAVERAKRFVEGAIRFSGGEGE
AVNPLWELQRDTQRWMAKEDLEKAVGELVKLGELLNPHVAEVGTNFALATDFGEVFAVKG
RIVRYGKTIKPVGPVELNASDHLRRALLKMREFYPEVRAVINLRYSEKLIKRAEKLGLKV
SFYDRREEPEEVKRAERGTMEWGIESAVKRLGEKPNVIYHLGDWGKEPMILVFGRNAEEI
VERIRNLIFASQ

NT seq 1299 nt +upstreamnt +downstreamnt
atggccgtgctcatcatagctggcctcgacactggcggcggggcagggctgaaggctgac
atcgaaaccgtctcggcccttggcgagcacccgctcccggtagtttccgcgataacctat
caaaacccggacgaggttaggggggtctttccagtaccaccaaatactatcagggaacag
ataagggccgttaagggtgtctttgaaattagggctgtcaaaataggccttcttcacggc
ggtgcagtgaaggtcatagccgaggagacgaaagggctcattagagtcctcgatccggtc
atagcttcctcttcaggctttcggtttttaagccctgaagatgtcgagatactgaagaga
gagctcctcccaggctcgatagttaccccgaacgtccctgaggcagaggttctaacgggc
ctgaaaataaactccatagaggacataaaaagggttgcacgagttctagtagaggagctg
ggcgcagaggctgctattgtcaagggtggacacctgaacttcaccgacgtcctctactgg
aatggggaggtcttcaagttttcaggggagagggttgagggcttcactcacgggacgggc
tgcgtcttctcttcggctctggcagctttcatagccaagggccttgagcttccgaaggcc
gtcgagagggcaaagcgcttcgtcgagggggcgataaggttctcagggggagaaggagag
gccgtcaatcctctctgggagcttcagagagatactcagaggtggatggccaaggaagat
cttgaaaaagcagtcggtgagcttgtgaaactcggcgaactcctgaacccgcacgttgct
gaggtaggcaccaactttgccctggcaactgacttcggcgaagtcttcgcagttaagggc
cgcattgtccgctacggcaaaacgataaagccagtggggccggttgagctcaacgccagc
gatcacctcaggagagctctcctgaagatgagggagttctaccccgaggtcagagcggtt
atcaacctccgctattcagagaagctcatcaagagggcagaaaagcttggactgaaggtt
tccttctacgaccgcagggaagagccggaggaagtcaagagggccgagaggggtacaatg
gagtggggcattgagagcgccgtgaaaaggcttggagagaagcccaacgtgatctatcac
ctcggcgactggggaaaggagccgatgatactcgtgtttggcaggaatgctgaagagatc
gtcgagagaataagaaaccttatttttgccagtcagtag

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