KEGG   Treponema pallidum subsp. pallidum Mexico A: TPAMA_0670
Entry
TPAMA_0670        CDS       T02273                                 
Symbol
ddl
Name
(GenBank) D-alanine--D-alanine ligase
  KO
K01921  D-alanine-D-alanine ligase [EC:6.3.2.4]
Organism
tpo  Treponema pallidum subsp. pallidum Mexico A
Pathway
tpo00470  D-Amino acid metabolism
tpo00550  Peptidoglycan biosynthesis
tpo01100  Metabolic pathways
tpo01502  Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:tpo00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00470 D-Amino acid metabolism
    TPAMA_0670 (ddl)
  09107 Glycan biosynthesis and metabolism
   00550 Peptidoglycan biosynthesis
    TPAMA_0670 (ddl)
 09160 Human Diseases
  09175 Drug resistance: antimicrobial
   01502 Vancomycin resistance
    TPAMA_0670 (ddl)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01011 Peptidoglycan biosynthesis and degradation proteins [BR:tpo01011]
    TPAMA_0670 (ddl)
Enzymes [BR:tpo01000]
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.2  Acid-D-amino-acid ligases (peptide synthases)
    6.3.2.4  D-alanine---D-alanine ligase
     TPAMA_0670 (ddl)
Peptidoglycan biosynthesis and degradation proteins [BR:tpo01011]
 Precursor biosynthesis
  Amino acid ligase
   TPAMA_0670 (ddl)
SSDB
Motif
Pfam: Dala_Dala_lig_C Dala_Dala_lig_N ATP-grasp CPSase_L_D2 ATPgrasp_ST
Other DBs
NCBI-ProteinID: AFU66658
Position
complement(736247..737437)
AA seq 396 aa
MVHVTLLYGGRSAEHDVSVRSARFVARTLCLQHTVMLIGITRRGVWYAQPACALEQLCTG
TVALSIQEDEKRRVCLVPGGGTAGAFVIAGMPCVTDVVFPVLHGSYGEDGTVQGLLEMLQ
VPYVGCGVCASALAMDKVKAKMLWQAAGLPVLPFVFFRKDAWRMHMQEFVAQLETRLGYP
LFVKPAQAGSSVGASAVQTRAPLIPAIEAAFQWDEVVLVERYVRAREIECALSGNGPYTV
HGAGEVIAQGAFYDYEEKYADASVARVLVTAPLETAQYEQITTLALRAYEALGLTGLARV
DFFLLETGEVYVNEVNTMPGFTSISLFPQICQAAGVAPQDLMAQLLSCARERFAARAALS
TDLHAHVCAPSVTAAHDPDAQGDDWDQRDSNPLPTA
NT seq 1191 nt   +upstreamnt  +downstreamnt
gtggtgcatgtgacgcttttgtacggaggccgttctgcagagcacgatgtttctgtacgt
tctgcacgttttgtggcgcgcacgttgtgcttacaacacaccgtaatgctcatcggtatt
acccgtcgtggcgtgtggtatgcgcagcctgcgtgtgcattagagcagttgtgtaccggc
actgtcgcgctcagtattcaggaagatgaaaagaggcgcgtgtgtcttgtcccgggaggt
ggtactgcaggcgcttttgtcatagcggggatgccgtgtgtcacggatgtggtattcccc
gtattgcatggcagttatggggaagatggtacggtgcagggtttgcttgagatgctgcag
gtgccgtacgtggggtgtggagtgtgtgcaagtgctcttgcgatggataaggtaaaggca
aagatgctatggcaggcggcgggacttcccgttttaccgtttgtctttttccgtaaagat
gcatggcgtatgcatatgcaagaatttgttgcgcagcttgaaacacgccttggctatcct
ctttttgtaaagccagctcaagcaggcagttccgtaggagccagtgcagtgcagacgcgt
gcaccgcttatccctgcgattgaagcggcttttcagtgggatgaagtggtgttggtggag
cgatatgtgcgcgcgcgagaaattgaatgtgcgctcagtgggaacggaccctatactgta
catggggcaggagaggtgattgcgcagggagccttttatgactacgaggaaaaatatgct
gatgcaagtgtcgcgcgtgtactcgttacggctcctcttgagactgcccagtacgaacag
attaccacacttgccctgcgcgcatacgaagcattaggactcacgggtctggcgcgggtt
gatttttttctgttagaaacgggagaagtatatgtgaacgaagtaaacacgatgccgggt
tttacgtcgatatcactctttccccaaatatgtcaggctgcaggtgttgcaccgcaggac
ttaatggcacaactcctttcttgcgcacgagagcgctttgcagcgcgcgccgcactgagc
accgacttgcacgcccacgtgtgtgcgccctcggtgactgctgcacatgaccccgatgcg
caaggggacgactgggaccagagggactcgaaccccctccctactgcttag

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