KEGG T00254: TP04

Theileria parva: TP04_0504

Entry

TP04_0504 CDS T00254

Definition

dihydrofolate reductase-thymidylate synthase (EC:1.5.1.3)

Orthology

K13998

dihydrofolate reductase / thymidylate synthase [EC:1.5.1.3 2.1.1.45]

Organism

tpv Theileria parva

Pathway

tpv00240	Pyrimidine metabolism
tpv00670	One carbon pool by folate
tpv00790	Folate biosynthesis
tpv01100	Metabolic pathways

Class

Metabolism; Nucleotide metabolism; Pyrimidine metabolism [PATH:tpv00240]
Metabolism; Metabolism of cofactors and vitamins; Folate biosynthesis [PATH:tpv00790]
Metabolism; Metabolism of cofactors and vitamins; One carbon pool by folate [PATH:tpv00670]

SSDB

Motif

Pfam:

Thymidylat_synt DHFR_1

Other DBs

NCBI-GI:

71028992

NCBI-GeneID:

3500994

UniProt:

Q4N262

Position

AA seq 522 aa
MAEDYSGLPFVKLLVAITPENGIGISNGLPWPHIKRDFLFMFRATTYVDPEFKEKHPGAQ
NVIIIGRKTYDSLPEGTFPLKNRINVVISRNLTEVPGGLVFPSMPAAIRHVTEHLNYYKI
FIMGIFHLNIKHLGGSYVYRDALDARIVDKMYVTRVNKNYKCEVFFPKIPDDFVITGISK
TFSSEDTTYDFVTYERKDLIVDDRVKKTFEEMLLTGEKFATKDQLVKACPSLKVRYSQEL
QYLEILADILNTGYHKKNRTGVDCIAKFGYQMRFDLSESFPLLTTKKVFLRGIIEELIWF
IKGSTNGNELLKKNVRIWELNGARSFLDNLGFFDREEHDLGPVYGFQWRHFGAKYVDMHT
DYSNQGIDQLSLVIDRIKNNPDNRRLIVCSWNVADLSKMALPPCHLLFQFFVADGTLSCM
MHQRSCDMGLGVPFNIASYSLLTYMIAQICGLKPGEFVHNLGDAHIYNNHIDAIKEQISR
VPYPFPTLRLNKDITRIEDFTIDDIKVENYRSHPVIKMEMAA

NT seq 1569 nt +upstreamnt +downstreamnt
atggcggaagattactctggattacctttcgttaaattgttagtagcgataacgccagaa
aatggaattggaatcagtaatggactaccatggccacacatcaaaagggactttcttttt
atgttcagggcaacgacttatgttgatccagaattcaaagaaaagcacccaggagctcaa
aatgtaataatcattggtagaaagacatacgatagccttccagaaggaacttttccactg
aagaacagaatcaacgttgttatatcaagaaatcttactgaggttccaggtggattagta
tttccttcaatgccagctgcgattcgtcacgttactgaacatctcaactactataagatc
ttcataatgggtatttttcatctaaatataaaacatttaggaggaagctacgtctatagg
gatgctcttgatgcaagaattgttgataaaatgtacgttacaagggtaaacaagaattac
aagtgtgaagtgttcttcccaaagatccctgatgacttcgttataactggaattagtaaa
acgttctcaagtgaagacacaacatatgactttgtgacgtacgaaagaaaagatttaatt
gttgatgatcgcgttaaaaaaacatttgaagagatgttgttgactggagagaaatttgca
actaaggatcaattggtgaaagcttgcccatcactgaaggttagatacagccaggaactt
cagtatcttgaaattctagctgacatcttaaacactggatatcacaaaaagaatagaaca
ggcgtggattgtattgcaaaattcggttaccaaatgaggtttgacctttcagaatcattt
ccgttattaacaacaaagaaagtcttcttaagaggaatcattgaggagcttatttggttt
attaaaggtagcacaaacggcaatgaattgctgaaaaagaatgtaagaatctgggagctg
aatggagcaagaagttttctggataacctgggattttttgatcgcgaagaacatgaccta
ggacctgtttacggattccaatggcgtcatttcggtgccaaatacgtagatatgcacaca
gactacagtaaccaaggaattgaccagctatcactggtcattgataggatcaagaataac
ccagataacagaagattgattgtgtgttcgtggaacgtagcagacctgtcaaagatggca
ttgcctccatgtcatctgctattccaattttttgtagcagatggaacattgtcgtgtatg
atgcaccaaaggtcatgtgatatgggactaggagtaccatttaacattgcatcatactca
ttactgacctacatgatagcccaaatatgtggactaaaaccgggagaatttgtacacaac
cttggagatgcccacatatacaataaccatattgacgcaatcaaggaacagattagtaga
gttccttatccattcccaaccctaagactaaacaaagatataacaaggattgaagacttc
acaatcgatgacattaaggtggaaaattaccgttcacacccggtaatcaagatggagatg
gctgcataa

All links

Pathway (4)   
   KEGG PATHWAY (4)   
Chemical substance (11)   
   KEGG COMPOUND (11)   
Chemical reaction (9)   
   KEGG ENZYME (2)   
   KEGG REACTION (7)   
Genome (1)   
   KEGG GENOME (1)   
Gene (4)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (1)   
   OC (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (2)   
   Pfam (2)   
All databases (34)   

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