ID   Q53657_STRAU            Unreviewed;       469 AA.
AC   Q53657;
DT   01-NOV-1996, integrated into UniProtKB/TrEMBL.
DT   01-NOV-1996, sequence version 1.
DT   19-JAN-2010, entry version 38.
DE   SubName: Full=6-hydroxylation enzyme of tetracycline;
GN   Name=cts8;
OS   Streptomyces aureofaciens.
OC   Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales;
OC   Streptomycineae; Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=1894;
RN   [1]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=NRRL3203;
RX   MEDLINE=95337551; PubMed=7612997;
RA   Dairi T., Nakano T., Aisaka K., Katsumata R., Hasegawa M.;
RT   "Cloning and nucleotide sequence of the gene responsible for
RT   chlorination of tetracycline.";
RL   Biosci. Biotechnol. Biochem. 59:1099-1106(1995).
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DR   EMBL; D38214; BAA07387.1; -; Genomic_DNA.
DR   PIR; JC4098; JC4098.
DR   GO; GO:0004497; F:monooxygenase activity; IEA:InterPro.
DR   GO; GO:0055114; P:oxidation reduction; IEA:InterPro.
DR   InterPro; IPR002938; mOase_FAD_bd.
DR   InterPro; IPR003042; Rng_hydrolase-like.
DR   Pfam; PF01494; FAD_binding_3; 1.
DR   PRINTS; PR00420; RNGMNOXGNASE.
PE   4: Predicted;
KW   Cyclin.
SQ   SEQUENCE   469 AA;  50448 MW;  A914F94452FD1052 CRC64;
     MVVAGAGPTG LMLACELALG GARAVVVERR REPEKHSKAM GMQGRTVELL ELRGLLDRFK
     EGAGVLQGGN FASLGVPMRF EEFDTQPTQY VLLVPQLRTE ELLAERAREL GVRIVRGSGV
     TGFAQDADGV TVETDTGLLR ARYLVGCDGG STVRKAAGIG FTGQDPHMYA LIGDMRFSGD
     LPRGEGLGPM RPVGLVYRAT VAWFDRPFAD RRAPVTEEEM RAALVEHTGS DHGMHDVTWL
     SRLTDVSRLA DSYRLGRVLL AGDAAHIHLP AGGQGLNLGF QDAVNLGWKL AAVVRGHGTE
     ELLDSYGRER RPIADGVVRN TRTQAVLIDP DPRYEALRQT LPHLMALPDT NRHMAGMLSG
     FDVAYGGGDH PLVGRRMPDA ELITADGPRR ISDCFAGARG LLLLPEQGPT ASPLAAWADR
     VDTLTVKSGG PDPDTAHLVR PDGYVAWAGE PARTEELHHA ATTWFGAAA
//