ID A0A061FTY6_THECC Unreviewed; 580 AA.
AC A0A061FTY6;
DT 03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT 03-SEP-2014, sequence version 1.
DT 27-MAR-2024, entry version 55.
DE SubName: Full=Histone deacetylase 15 isoform 1 {ECO:0000313|EMBL:EOY20940.1};
GN ORFNames=TCM_012263 {ECO:0000313|EMBL:EOY20940.1};
OS Theobroma cacao (Cacao) (Cocoa).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Malvales; Malvaceae; Byttnerioideae; Theobroma.
OX NCBI_TaxID=3641 {ECO:0000313|EMBL:EOY20940.1, ECO:0000313|Proteomes:UP000026915};
RN [1] {ECO:0000313|EMBL:EOY20940.1, ECO:0000313|Proteomes:UP000026915}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Matina 1-6 {ECO:0000313|Proteomes:UP000026915};
RX PubMed=23731509; DOI=10.1186/gb-2013-14-6-r53;
RA Motamayor J.C., Mockaitis K., Schmutz J., Haiminen N., Iii D.L.,
RA Cornejo O., Findley S.D., Zheng P., Utro F., Royaert S., Saski C.,
RA Jenkins J., Podicheti R., Zhao M., Scheffler B.E., Stack J.C., Feltus F.A.,
RA Mustiga G.M., Amores F., Phillips W., Marelli J.P., May G.D., Shapiro H.,
RA Ma J., Bustamante C.D., Schnell R.J., Main D., Gilbert D., Parida L.,
RA Kuhn D.N.;
RT "The genome sequence of the most widely cultivated cacao type and its use
RT to identify candidate genes regulating pod color.";
RL Genome Biol. 14:R53.1-R53.24(2013).
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947};
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CM001881; EOY20940.1; -; Genomic_DNA.
DR RefSeq; XP_007036439.1; XM_007036377.2.
DR AlphaFoldDB; A0A061FTY6; -.
DR SMR; A0A061FTY6; -.
DR STRING; 3641.A0A061FTY6; -.
DR EnsemblPlants; EOY20940; EOY20940; TCM_012263.
DR EnsemblPlants; Tc03v2_t002080.1; Tc03v2_p002080.1; Tc03v2_g002080.
DR GeneID; 18604061; -.
DR Gramene; EOY20940; EOY20940; TCM_012263.
DR Gramene; Tc03v2_t002080.1; Tc03v2_p002080.1; Tc03v2_g002080.
DR KEGG; tcc:18604061; -.
DR eggNOG; KOG1343; Eukaryota.
DR InParanoid; A0A061FTY6; -.
DR OMA; VCGEHRE; -.
DR OrthoDB; 124800at2759; -.
DR Proteomes; UP000026915; Chromosome 3.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0000118; C:histone deacetylase complex; IBA:GO_Central.
DR GO; GO:0004407; F:histone deacetylase activity; IBA:GO_Central.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0000122; P:negative regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR CDD; cd09992; HDAC_classII; 1.
DR Gene3D; 3.40.800.20; Histone deacetylase domain; 1.
DR InterPro; IPR000286; His_deacetylse.
DR InterPro; IPR023801; His_deacetylse_dom.
DR InterPro; IPR037138; His_deacetylse_dom_sf.
DR InterPro; IPR023696; Ureohydrolase_dom_sf.
DR InterPro; IPR001876; Znf_RanBP2.
DR PANTHER; PTHR10625:SF16; HISTONE DEACETYLASE 15; 1.
DR PANTHER; PTHR10625; HISTONE DEACETYLASE HDAC1-RELATED; 1.
DR Pfam; PF00850; Hist_deacetyl; 1.
DR PRINTS; PR01270; HDASUPER.
DR SUPFAM; SSF52768; Arginase/deacetylase; 1.
DR PROSITE; PS01358; ZF_RANBP2_1; 1.
PE 4: Predicted;
KW Chromatin regulator {ECO:0000256|ARBA:ARBA00022853};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000026915};
KW Repressor {ECO:0000256|ARBA:ARBA00022491};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 112..131
FT /note="RanBP2-type"
FT /evidence="ECO:0000259|PROSITE:PS01358"
FT REGION 1..25
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 42..77
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..19
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 580 AA; 64059 MW; 66D37DFFE7478EAC CRC64;
MVSETVQVSC VTNGGAKNNQ GFKRKHLGSD ENTTACCHDE VSDDKGDIGT SGRDTSTNIN
DDTQPDGVSK RKRLPKELTF QDMYNNQDAF DDDDEDDSDW EPVQKHLEIL KWFCTNCTMV
NLDDVVHCDI CGEHKESGIL KHGFYASPCS PELDLIQVES EARERDKDLR FEASASNCST
AVGFDERMLL HSEVEMKSHP HPERPDRLRA IAASLAVAGI FPGKCYPIPA REITQEELRR
VHSLEHIETV ELTSQILSSY FTPDTYANEH SAYAARLAAG LCANLASAIF SGRVRNGFAL
VRPPGHHAGV TQAMGFCLHN NAAVAALAAQ AAGAKKVLIV DWDVHHGNGT QEIFEQNKSV
LYISLHRHEG GKFYPGTGAA FEVGSKGAEG YCVNIPWSRG GVGDNDYIFA FQHVVLPIAS
KFSPDFTIIS AGFDAARGDP LGCCDVTPAG YAQMTHMLSA LSGGRLLVIL EGGYNLRSIS
SSATAVIKVL LGESSGYEPE NIVPSKSGLH TVLEVLKIQM KYWPPLSSSY EKLQSQWGMY
SMENKKKQVK KRRLFEPPLW WRWGRKQLLY HILTGHFHLK
//
