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Database: UniProt/TrEMBL
Entry: A0A0B6AKH4_BACMB
LinkDB: A0A0B6AKH4_BACMB
Original site: A0A0B6AKH4_BACMB 
ID   A0A0B6AKH4_BACMB        Unreviewed;       922 AA.
AC   A0A0B6AKH4;
DT   01-APR-2015, integrated into UniProtKB/TrEMBL.
DT   01-APR-2015, sequence version 1.
DT   22-NOV-2017, entry version 21.
DE   RecName: Full=Phosphoenolpyruvate carboxylase {ECO:0000256|HAMAP-Rule:MF_00595, ECO:0000256|SAAS:SAAS00946768};
DE            Short=PEPC {ECO:0000256|HAMAP-Rule:MF_00595};
DE            Short=PEPCase {ECO:0000256|HAMAP-Rule:MF_00595};
DE            EC=4.1.1.31 {ECO:0000256|HAMAP-Rule:MF_00595, ECO:0000256|SAAS:SAAS00946768};
GN   Name=ppc {ECO:0000256|HAMAP-Rule:MF_00595};
GN   ORFNames=BG04_3106 {ECO:0000313|EMBL:AJI21547.1};
OS   Bacillus megaterium (strain ATCC 14581 / DSM 32 / JCM 2506 / NBRC
OS   15308 / NCIMB 9376 / NCTC 10342 / VKM B-512).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=1348623 {ECO:0000313|EMBL:AJI21547.1, ECO:0000313|Proteomes:UP000031829};
RN   [1] {ECO:0000313|EMBL:AJI21547.1, ECO:0000313|Proteomes:UP000031829}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 14581 / DSM 32 / JCM 2506 / NBRC 15308 / NCIMB 9376 /
RC   NCTC 10342 / VKM B-512 {ECO:0000313|Proteomes:UP000031829};
RX   PubMed=25931591;
RA   Johnson S.L., Daligault H.E., Davenport K.W., Jaissle J., Frey K.G.,
RA   Ladner J.T., Broomall S.M., Bishop-Lilly K.A., Bruce D.C.,
RA   Gibbons H.S., Coyne S.R., Lo C.C., Meincke L., Munk A.C.,
RA   Koroleva G.I., Rosenzweig C.N., Palacios G.F., Redden C.L.,
RA   Minogue T.D., Chain P.S.;
RT   "Complete genome sequences for 35 biothreat assay-relevant bacillus
RT   species.";
RL   Genome Announc. 3:0-0(2015).
CC   -!- FUNCTION: Forms oxaloacetate, a four-carbon dicarboxylic acid
CC       source for the tricarboxylic acid cycle. {ECO:0000256|HAMAP-
CC       Rule:MF_00595, ECO:0000256|SAAS:SAAS00946761}.
CC   -!- CATALYTIC ACTIVITY: Phosphate + oxaloacetate = H(2)O +
CC       phosphoenolpyruvate + HCO(3)(-). {ECO:0000256|HAMAP-Rule:MF_00595,
CC       ECO:0000256|SAAS:SAAS00946751}.
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000256|HAMAP-
CC         Rule:MF_00595, ECO:0000256|SAAS:SAAS00946766};
CC   -!- SUBUNIT: Homotetramer. {ECO:0000256|HAMAP-Rule:MF_00595}.
CC   -!- SIMILARITY: Belongs to the PEPCase type 1 family.
CC       {ECO:0000256|HAMAP-Rule:MF_00595, ECO:0000256|SAAS:SAAS00946753}.
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DR   EMBL; CP009920; AJI21547.1; -; Genomic_DNA.
DR   RefSeq; WP_016763122.1; NZ_JJMH01000063.1.
DR   EnsemblBacteria; AJI21547; AJI21547; BG04_3106.
DR   GeneID; 29907233; -.
DR   KEGG; bmeg:BG04_3106; -.
DR   KO; K01595; -.
DR   Proteomes; UP000031829; Chromosome.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0008964; F:phosphoenolpyruvate carboxylase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0015977; P:carbon fixation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006107; P:oxaloacetate metabolic process; IEA:UniProtKB-UniRule.
DR   GO; GO:0006099; P:tricarboxylic acid cycle; IEA:InterPro.
DR   HAMAP; MF_00595; PEPcase_type1; 1.
DR   InterPro; IPR021135; PEP_COase.
DR   InterPro; IPR022805; PEP_COase_bac/pln-type.
DR   InterPro; IPR018129; PEP_COase_Lys_AS.
DR   InterPro; IPR015813; Pyrv/PenolPyrv_Kinase-like_dom.
DR   PANTHER; PTHR30523; PTHR30523; 1.
DR   Pfam; PF00311; PEPcase; 1.
DR   PRINTS; PR00150; PEPCARBXLASE.
DR   SUPFAM; SSF51621; SSF51621; 1.
DR   PROSITE; PS00781; PEPCASE_1; 1.
PE   3: Inferred from homology;
KW   Carbon dioxide fixation {ECO:0000256|HAMAP-Rule:MF_00595,
KW   ECO:0000256|SAAS:SAAS00946757};
KW   Complete proteome {ECO:0000313|Proteomes:UP000031829};
KW   Lyase {ECO:0000256|HAMAP-Rule:MF_00595,
KW   ECO:0000256|SAAS:SAAS00946754};
KW   Magnesium {ECO:0000256|HAMAP-Rule:MF_00595,
KW   ECO:0000256|SAAS:SAAS00946750};
KW   Pyruvate {ECO:0000313|EMBL:AJI21547.1}.
FT   ACT_SITE    152    152       {ECO:0000256|HAMAP-Rule:MF_00595,
FT                                ECO:0000256|PROSITE-ProRule:PRU10111}.
FT   ACT_SITE    579    579       {ECO:0000256|HAMAP-Rule:MF_00595}.
SQ   SEQUENCE   922 AA;  105985 MW;  44CB8D90BE3230CA CRC64;
     MVTVEAAERQ NSSTALRRDV KFLGQLLGKV LVHQGGEELL SKVEKIREVA KSLRENKDEV
     IYKEIKNEIV TLEQPMREQV IRAFAVYFHL VNIAEQNHRI RRRREYQQQE DSIMQPGSLE
     SAVVSLKNNG VAPDVIANLL QTLSLELIIT AHPTEATRRS VLDIHKRMAE LLKNLDNPTL
     TKRERTEIEE RLFSEVLILW QTNELRDRKP TVMDEVSNGL YYFDETLFEV LPQLHQELEN
     SLQENYPEEN WKVPNILRFG SWIGGDRDGN PNVTPKVTWQ TLVKQRKLAI RKYKESLTQL
     RQRLSQSTKR VAVSDNLLDS INQEISLLPE KKRWRIKHEV YRCKLTIMLH KLNLVGESEA
     GYQRSEELLH DLFLIKDSLQ KHQPQDYQLK SLCKLIRQVE LFGFHLATLD IRNHSGEHEA
     AIKEIFHAVS LAEDYSALTE EKKVELLGKV LQDPRPVISF VENYSKETQQ VIEVFNMIHR
     AHKEFGERSI EVYLISMTQS ASDLLEVMVL AKEAGIYRLH ADGRIESKLN IAPLLETIDD
     LTAGPKIMEQ LFQLDFYREH LRKQQDLQEI MLGYSDGSKD GGTLTANWKL YKAQQEIHDM
     AKKYQVRLKF FHGRGGSLGR GGGPLNRSIL SQPVETLGDG VKITEQGEVL SSRYALYDIA
     YRSLEQAVSA LLTAAANVSQ EAEQCDIRTH EWEETMDEIS TASLRKYQEL VFKDPDFLTY
     FKQATPLPEL GALNIGSRPM SRKGSDRFED LRAIPWVFAW TQSRQLLPAW YAAGTGLQHL
     VEKSGDIQLL QQMYKEWPFF RSTVDNLQMA LTKADLMAAK EYTEMVQDPA ISERIFTAIK
     KEYNLTKEMI LQITGQKELM DHLPTIKESI KLRNPYVDPL TFLQVKVISK LREDEAGTLN
     EELLKEALLT INGIAAGLRN TG
//
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