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Database: UniProt/TrEMBL
Entry: A0A0D0ID86_HAEIF
LinkDB: A0A0D0ID86_HAEIF
Original site: A0A0D0ID86_HAEIF 
ID   A0A0D0ID86_HAEIF        Unreviewed;       394 AA.
AC   A0A0D0ID86;
DT   29-APR-2015, integrated into UniProtKB/TrEMBL.
DT   29-APR-2015, sequence version 1.
DT   05-JUL-2017, entry version 20.
DE   RecName: Full=Elongation factor Tu {ECO:0000256|HAMAP-Rule:MF_00118, ECO:0000256|RuleBase:RU004061};
DE            Short=EF-Tu {ECO:0000256|HAMAP-Rule:MF_00118};
GN   Name=tuf {ECO:0000256|HAMAP-Rule:MF_00118,
GN   ECO:0000313|EMBL:KIP48556.1};
GN   Synonyms=tuf_1 {ECO:0000313|EMBL:CWX44008.1}, tufA_2
GN   {ECO:0000313|EMBL:KIS36058.1};
GN   ORFNames=ABN48_00685 {ECO:0000313|EMBL:KMZ29466.1}, BV935_01465
GN   {ECO:0000313|EMBL:OMQ00351.1}, BV935_06775
GN   {ECO:0000313|EMBL:OMP96128.1}, ERS515286_01424
GN   {ECO:0000313|EMBL:CWX44008.1}, NTHI1209_01698
GN   {ECO:0000313|EMBL:KIS36058.1}, SU59_07265
GN   {ECO:0000313|EMBL:KIP48556.1};
OS   Haemophilus influenzae.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC   Pasteurellaceae; Haemophilus.
OX   NCBI_TaxID=727 {ECO:0000313|EMBL:KIP48556.1, ECO:0000313|Proteomes:UP000032058};
RN   [1] {ECO:0000313|EMBL:KIS36058.1, ECO:0000313|Proteomes:UP000050700}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=1209 {ECO:0000313|EMBL:KIS36058.1,
RC   ECO:0000313|Proteomes:UP000050700};
RA   Atack J.M., Fox K.L., Power P.M., Clark T., Jurcisek J., Korlach J.,
RA   Bakaletz L.O., Jennings M.P.;
RT   "Methylome analysis of the phasevarions of Haemophilus influenzae.";
RL   Submitted (MAY-2014) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:KIP48556.1, ECO:0000313|Proteomes:UP000032058}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=RMHi93 {ECO:0000313|EMBL:KIP48556.1,
RC   ECO:0000313|Proteomes:UP000032058};
RA   Giufre M., De Chiara M., Guidotti S., Torricelli G., De Angelis G.,
RA   Cardines R., Pizza M., Censini S., Muzzi A., Cerquetti M., Soriani M.;
RT   "Whole-genome sequences of nonencapsulated Haemophilus influenzae
RT   strains isolated in Italy.";
RL   Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
RN   [3] {ECO:0000313|EMBL:KMZ29466.1, ECO:0000313|Proteomes:UP000037430}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=HI1408 {ECO:0000313|EMBL:KMZ29466.1,
RC   ECO:0000313|Proteomes:UP000037430};
RA   VanWagoner T.M., Mussa H., Whitby P.W., Morton D.J., Seale T.W.,
RA   Stull T.L.;
RT   "Genome sequences of invasive non-typeable Haemophilus influenzae.";
RL   Submitted (JUN-2015) to the EMBL/GenBank/DDBJ databases.
RN   [4] {ECO:0000313|EMBL:CWX44008.1, ECO:0000313|Proteomes:UP000074061}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=2842STDY5882080 {ECO:0000313|EMBL:CWX44008.1,
RC   ECO:0000313|Proteomes:UP000074061};
RG   Pathogen Informatics;
RL   Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
RN   [5] {ECO:0000313|EMBL:OMP96128.1, ECO:0000313|Proteomes:UP000189053}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=hi467 {ECO:0000313|Proteomes:UP000189053}, and Hi467
RC   {ECO:0000313|EMBL:OMP96128.1};
RA   Giufre' M., Cardines R., Cerquetti M.;
RT   "Whole-Genome sequence of a Haemophilus influenzae type e strain
RT   isolated from invasive disease, in Italy.";
RL   Submitted (JAN-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: This protein promotes the GTP-dependent binding of
CC       aminoacyl-tRNA to the A-site of ribosomes during protein
CC       biosynthesis. {ECO:0000256|HAMAP-Rule:MF_00118}.
CC   -!- SUBUNIT: Monomer. {ECO:0000256|HAMAP-Rule:MF_00118}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00118}.
CC   -!- SIMILARITY: Belongs to the TRAFAC class translation factor GTPase
CC       superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A
CC       subfamily. {ECO:0000256|HAMAP-Rule:MF_00118}.
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DR   EMBL; FFIP01000003; CWX44008.1; -; Genomic_DNA.
DR   EMBL; JXMH01000027; KIP48556.1; -; Genomic_DNA.
DR   EMBL; JMQP01000002; KIS36058.1; -; Genomic_DNA.
DR   EMBL; LFDJ01000003; KMZ29466.1; -; Genomic_DNA.
DR   EMBL; MTBH01000037; OMP96128.1; -; Genomic_DNA.
DR   EMBL; MTBH01000005; OMQ00351.1; -; Genomic_DNA.
DR   RefSeq; WP_005667564.1; NZ_MTGI01000004.1.
DR   SMR; A0A0D0ID86; -.
DR   EnsemblBacteria; CWX44008; CWX44008; ERS515286_01424.
DR   EnsemblBacteria; KIP48556; KIP48556; SU59_07265.
DR   EnsemblBacteria; KIS36058; KIS36058; NTHI1209_01698.
DR   EnsemblBacteria; KMZ29466; KMZ29466; ABN48_00685.
DR   KEGG; hic:NTHIC486_00411; -.
DR   KEGG; hih:NF38_01990; -.
DR   KEGG; hih:NF38_02185; -.
DR   KEGG; hix:NTHI723_01074; -.
DR   PATRIC; fig|727.529.peg.482; -.
DR   eggNOG; ENOG4105CGV; Bacteria.
DR   eggNOG; COG0050; LUCA.
DR   KO; K02358; -.
DR   Proteomes; UP000032058; Unassembled WGS sequence.
DR   Proteomes; UP000037430; Unassembled WGS sequence.
DR   Proteomes; UP000050700; Unassembled WGS sequence.
DR   Proteomes; UP000074061; Unassembled WGS sequence.
DR   Proteomes; UP000189053; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR   GO; GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-HAMAP.
DR   CDD; cd03697; EFTU_II; 1.
DR   HAMAP; MF_00118_B; EF_Tu_B; 1.
DR   InterPro; IPR004161; EFTu-like_2.
DR   InterPro; IPR033720; EFTU_2.
DR   InterPro; IPR031157; G_TR_CS.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR005225; Small_GTP-bd_dom.
DR   InterPro; IPR000795; TF_GTP-bd_dom.
DR   InterPro; IPR009000; Transl_B-barrel.
DR   InterPro; IPR009001; Transl_elong_EF1A/Init_IF2_C.
DR   InterPro; IPR004541; Transl_elong_EFTu/EF1A_bac/org.
DR   InterPro; IPR004160; Transl_elong_EFTu/EF1A_C.
DR   Pfam; PF00009; GTP_EFTU; 1.
DR   Pfam; PF03144; GTP_EFTU_D2; 1.
DR   Pfam; PF03143; GTP_EFTU_D3; 1.
DR   PRINTS; PR00315; ELONGATNFCT.
DR   SUPFAM; SSF50447; SSF50447; 1.
DR   SUPFAM; SSF50465; SSF50465; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00485; EF-Tu; 1.
DR   TIGRFAMs; TIGR00231; small_GTP; 1.
DR   PROSITE; PS00301; G_TR_1; 1.
DR   PROSITE; PS51722; G_TR_2; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000032058,
KW   ECO:0000313|Proteomes:UP000037430, ECO:0000313|Proteomes:UP000050700,
KW   ECO:0000313|Proteomes:UP000074061};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00118};
KW   Elongation factor {ECO:0000256|HAMAP-Rule:MF_00118,
KW   ECO:0000313|EMBL:CWX44008.1};
KW   GTP-binding {ECO:0000256|HAMAP-Rule:MF_00118};
KW   Hydrolase {ECO:0000313|EMBL:KIP48556.1};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00118};
KW   Protein biosynthesis {ECO:0000256|HAMAP-Rule:MF_00118}.
FT   DOMAIN       10    204       Tr-type G (guanine nucleotide-binding).
FT                                {ECO:0000259|PROSITE:PS51722}.
FT   NP_BIND      19     26       GTP. {ECO:0000256|HAMAP-Rule:MF_00118}.
FT   NP_BIND      81     85       GTP. {ECO:0000256|HAMAP-Rule:MF_00118}.
FT   NP_BIND     136    139       GTP. {ECO:0000256|HAMAP-Rule:MF_00118}.
SQ   SEQUENCE   394 AA;  43354 MW;  79AC25FAAF3CEE26 CRC64;
     MSKEKFERTK PHVNVGTIGH VDHGKTTLTA AITTVLAKHY GGAARAFDQI DNAPEEKARG
     ITINTSHVEY DTPTRHYAHV DCPGHADYVK NMITGAAQMD GAILVVAATD GPMPQTREHI
     LLGRQVGVPY IIVFLNKCDM VDDEELLELV EMEVRELLSQ YDFPGDDTPI VRGSALQALN
     GVAEWEEKIL ELANHLDTYI PEPERAIDQP FLLPIEDVFS ISGRGTVVTG RVERGIIRTG
     DEVEIVGIKD TAKTTVTGVE MFRKLLDEGR AGENIGALLR GTKREEIERG QVLAKPGSIT
     PHTDFESEVY VLSKDEGGRH TPFFKGYRPQ FYFRTTDVTG TIELPEGVEM VMPGDNIKMT
     VSLIHPIAMD QGLRFAIREG GRTVGAGVVA KIIK
//
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