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Database: UniProt/TrEMBL
Entry: A0A0D6ISA5_SALTM
LinkDB: A0A0D6ISA5_SALTM
Original site: A0A0D6ISA5_SALTM 
ID   A0A0D6ISA5_SALTM        Unreviewed;       883 AA.
AC   A0A0D6ISA5;
DT   27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT   27-MAY-2015, sequence version 1.
DT   31-JAN-2018, entry version 29.
DE   RecName: Full=Phosphoenolpyruvate carboxylase {ECO:0000256|HAMAP-Rule:MF_00595, ECO:0000256|SAAS:SAAS00946768};
DE            Short=PEPC {ECO:0000256|HAMAP-Rule:MF_00595};
DE            Short=PEPCase {ECO:0000256|HAMAP-Rule:MF_00595};
DE            EC=4.1.1.31 {ECO:0000256|HAMAP-Rule:MF_00595, ECO:0000256|SAAS:SAAS00946768};
GN   Name=ppc {ECO:0000256|HAMAP-Rule:MF_00595};
GN   ORFNames=CR079_11880 {ECO:0000313|EMBL:PHM98316.1}, CR080_03710
GN   {ECO:0000313|EMBL:PHM94632.1}, CR081_18290
GN   {ECO:0000313|EMBL:PHK76379.1}, CR082_19235
GN   {ECO:0000313|EMBL:PHK81076.1}, CR083_16455
GN   {ECO:0000313|EMBL:PHK87135.1}, CR084_15050
GN   {ECO:0000313|EMBL:PHP36905.1}, CR085_15360
GN   {ECO:0000313|EMBL:PHP31737.1}, CR086_21795
GN   {ECO:0000313|EMBL:PHP60424.1}, CS350_17575
GN   {ECO:0000313|EMBL:PHZ87968.1}, CTI29_23220
GN   {ECO:0000313|EMBL:ATU62595.1}, DD95_08085
GN   {ECO:0000313|EMBL:KTZ13612.1};
OS   Salmonella typhimurium.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=90371 {ECO:0000313|EMBL:KTZ13612.1, ECO:0000313|Proteomes:UP000054461};
RN   [1] {ECO:0000313|EMBL:KTZ13612.1, ECO:0000313|Proteomes:UP000054461}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CVM N32045 {ECO:0000313|EMBL:KTZ13612.1,
RC   ECO:0000313|Proteomes:UP000054461};
RA   Chen Y., Folster J., Ayers S., Kabera C., Li C., Mukherjee S., Lam C.,
RA   Zhao S., McDermott P.;
RT   "Salmonella Genotype and Phenotype Association.";
RL   Submitted (SEP-2014) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Proteomes:UP000221873, ECO:0000313|Proteomes:UP000222775, ECO:0000313|Proteomes:UP000223380}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SE368 {ECO:0000313|EMBL:PHM98316.1,
RC   ECO:0000313|Proteomes:UP000222775}, SE373
RC   {ECO:0000313|EMBL:PHM94632.1, ECO:0000313|Proteomes:UP000221873},
RC   SE376 {ECO:0000313|EMBL:PHK76379.1,
RC   ECO:0000313|Proteomes:UP000225473}, SE389
RC   {ECO:0000313|EMBL:PHK81076.1, ECO:0000313|Proteomes:UP000224379},
RC   SE426 {ECO:0000313|EMBL:PHK87135.1,
RC   ECO:0000313|Proteomes:UP000223380}, SE484
RC   {ECO:0000313|EMBL:PHP36905.1, ECO:0000313|Proteomes:UP000226254},
RC   SE492 {ECO:0000313|EMBL:PHP31737.1,
RC   ECO:0000313|Proteomes:UP000224064}, and SE494
RC   {ECO:0000313|EMBL:PHP60424.1, ECO:0000313|Proteomes:UP000223987};
RA   Sanad Y., Khajanchi B., Deck J., Cox J., Thaker R., Han J., Nayak R.,
RA   Foley S.;
RT   "Characterization of the Virulence Potential of Salmonella enterica
RT   Isolates Carrying Incompatibility Group FIB Plasmids using Caco-2
RT   Intestinal Epithelial Cells.";
RL   Submitted (OCT-2017) to the EMBL/GenBank/DDBJ databases.
RN   [3] {ECO:0000313|EMBL:PHZ87968.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=CFSAN070646 {ECO:0000313|EMBL:PHZ87968.1};
RA   Hoffmann M., Timme R., Sanchez M., Binet R.;
RT   "Construction of stable fluorescent laboratory control strains.";
RL   Submitted (OCT-2017) to the EMBL/GenBank/DDBJ databases.
RN   [4] {ECO:0000313|EMBL:ATU62595.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=BL10 {ECO:0000313|EMBL:ATU62595.1};
RA   Banno H., Chua N.-H.;
RL   Submitted (OCT-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Forms oxaloacetate, a four-carbon dicarboxylic acid
CC       source for the tricarboxylic acid cycle. {ECO:0000256|HAMAP-
CC       Rule:MF_00595, ECO:0000256|SAAS:SAAS00946761}.
CC   -!- CATALYTIC ACTIVITY: Phosphate + oxaloacetate = H(2)O +
CC       phosphoenolpyruvate + HCO(3)(-). {ECO:0000256|HAMAP-Rule:MF_00595,
CC       ECO:0000256|SAAS:SAAS00946751}.
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000256|HAMAP-
CC         Rule:MF_00595, ECO:0000256|SAAS:SAAS00946766};
CC   -!- SUBUNIT: Homotetramer. {ECO:0000256|HAMAP-Rule:MF_00595}.
CC   -!- SIMILARITY: Belongs to the PEPCase type 1 family.
CC       {ECO:0000256|HAMAP-Rule:MF_00595, ECO:0000256|SAAS:SAAS00946753}.
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DR   EMBL; CP024619; ATU62595.1; -; Genomic_DNA.
DR   EMBL; JYVU01000017; KTZ13612.1; -; Genomic_DNA.
DR   EMBL; PDNM01000022; PHK76379.1; -; Genomic_DNA.
DR   EMBL; PDNL01000027; PHK81076.1; -; Genomic_DNA.
DR   EMBL; PDNK01000030; PHK87135.1; -; Genomic_DNA.
DR   EMBL; PDNN01000004; PHM94632.1; -; Genomic_DNA.
DR   EMBL; PDNO01000013; PHM98316.1; -; Genomic_DNA.
DR   EMBL; PDOJ01000018; PHP31737.1; -; Genomic_DNA.
DR   EMBL; PDOI01000054; PHP36905.1; -; Genomic_DNA.
DR   EMBL; PDOK01000033; PHP60424.1; -; Genomic_DNA.
DR   EMBL; PEHQ01000012; PHZ87968.1; -; Genomic_DNA.
DR   RefSeq; WP_001005548.1; NZ_PEHQ01000012.1.
DR   EnsemblBacteria; KKE08475; KKE08475; TJ44_01455.
DR   EnsemblBacteria; KTZ13612; KTZ13612; DD95_08085.
DR   KEGG; seni:CY43_21530; -.
DR   PATRIC; fig|90371.1185.peg.4480; -.
DR   KO; K01595; -.
DR   Proteomes; UP000054461; Unassembled WGS sequence.
DR   Proteomes; UP000221873; Unassembled WGS sequence.
DR   Proteomes; UP000222775; Unassembled WGS sequence.
DR   Proteomes; UP000223380; Unassembled WGS sequence.
DR   Proteomes; UP000223987; Unassembled WGS sequence.
DR   Proteomes; UP000224064; Unassembled WGS sequence.
DR   Proteomes; UP000224379; Unassembled WGS sequence.
DR   Proteomes; UP000225473; Unassembled WGS sequence.
DR   Proteomes; UP000226254; Unassembled WGS sequence.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0008964; F:phosphoenolpyruvate carboxylase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0015977; P:carbon fixation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006107; P:oxaloacetate metabolic process; IEA:UniProtKB-UniRule.
DR   GO; GO:0006099; P:tricarboxylic acid cycle; IEA:InterPro.
DR   HAMAP; MF_00595; PEPcase_type1; 1.
DR   InterPro; IPR021135; PEP_COase.
DR   InterPro; IPR022805; PEP_COase_bac/pln-type.
DR   InterPro; IPR018129; PEP_COase_Lys_AS.
DR   InterPro; IPR033129; PEPCASE_His_AS.
DR   InterPro; IPR015813; Pyrv/PenolPyrv_Kinase-like_dom.
DR   PANTHER; PTHR30523; PTHR30523; 1.
DR   Pfam; PF00311; PEPcase; 1.
DR   PRINTS; PR00150; PEPCARBXLASE.
DR   SUPFAM; SSF51621; SSF51621; 1.
DR   PROSITE; PS00781; PEPCASE_1; 1.
DR   PROSITE; PS00393; PEPCASE_2; 1.
PE   3: Inferred from homology;
KW   Carbon dioxide fixation {ECO:0000256|HAMAP-Rule:MF_00595,
KW   ECO:0000256|SAAS:SAAS00946757};
KW   Complete proteome {ECO:0000313|Proteomes:UP000054461,
KW   ECO:0000313|Proteomes:UP000221873, ECO:0000313|Proteomes:UP000222775,
KW   ECO:0000313|Proteomes:UP000223380};
KW   Lyase {ECO:0000256|HAMAP-Rule:MF_00595, ECO:0000256|SAAS:SAAS00946754,
KW   ECO:0000313|EMBL:KTZ13612.1};
KW   Magnesium {ECO:0000256|HAMAP-Rule:MF_00595,
KW   ECO:0000256|SAAS:SAAS00946750};
KW   Pyruvate {ECO:0000313|EMBL:KTZ13612.1}.
FT   ACT_SITE    138    138       {ECO:0000256|HAMAP-Rule:MF_00595,
FT                                ECO:0000256|PROSITE-ProRule:PRU10111}.
FT   ACT_SITE    546    546       {ECO:0000256|HAMAP-Rule:MF_00595,
FT                                ECO:0000256|PROSITE-ProRule:PRU10112}.
SQ   SEQUENCE   883 AA;  99003 MW;  2F28CE22308A003E CRC64;
     MNEQYSALRS NVSMLGKVLG ETIKDALGEH ILDRVETIRK LSKSSRAGNE ANRQELLTTL
     QNLSNDELLP VARAFSQFLN LANTAEQYHS ISPKGEAASN PEVIARTLRK LKNQPDLNDA
     TIKKAVESLS LELVLTAHPT EITRRTLIHK MGEINNCLKQ LDNTDIADYE RHQVMRRLRQ
     LIAQSWHTDE IRKQRPSPVD EAKWGFAVVE NSLWQGVPNY LRELNEQLEE NLGYKLPVDF
     VPVRFTSWMG GDRDGNPNVT ADITRHVLLL SRWKATDLFL KDIHVLVSEL SMVDATPELL
     ALVGEEGASE PYRYLMKKLR ARLMATQSWL EARLKGEKLP KPAGLLTQNE QLWEPLYACY
     QSLQACGMGI IANGELLDTL RRVKCFGVPL VRIDIRQEST RHTEALGEIT RYLGIGDYES
     WSEADKQAFL IRELNSKRPL LPRNWEPSND TREVLETCKV IAEAPKGSIA AYVISMAKTP
     SDVLAVHLLL KEAGIGFAMP VAPLFETLDD LNNADDVMTQ LLNIDWYRGL IQGKQMVMIG
     YSDSAKDAGV MAASWAQYQA QDALIKTCEK AGIELTLFHG RGGSIGRGGA PAHAALLSQP
     PGSLKGGLRV TEQGEMIRFK YGLPEVTVSS LSLYTSAILE ANLLPPPEPK DSWRHIMDEL
     SVISCETYRG YVRENKDFVP YFRSATPEQE LGKLPLGSRP AKRRPTGGVE SLRAIPWIFA
     WTQNRLMLPA WLGAGTALQK VVEDGKQSEL EAMCRDWPFF STRLGMLEMV FSKADLWLAD
     YYDQRLVAKT LWPLGKELRD LLEEDIKVVL AIANDSHLMA DLPWIAESIQ LRNVYTDPLN
     VLQAELLYRS RLTEEQGKSP DPRVEQALMV TIAGVAAGMR NTG
//
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