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Database: UniProt/TrEMBL
Entry: A0A0E1EJL9_STRAG
LinkDB: A0A0E1EJL9_STRAG
Original site: A0A0E1EJL9_STRAG 
ID   A0A0E1EJL9_STRAG        Unreviewed;       816 AA.
AC   A0A0E1EJL9;
DT   27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT   27-MAY-2015, sequence version 1.
DT   07-JUN-2017, entry version 20.
DE   SubName: Full=Sialidase {ECO:0000313|EMBL:AIF87430.1};
GN   ORFNames=AX245_10430 {ECO:0000313|EMBL:OCM71612.1}, EN72_10135
GN   {ECO:0000313|EMBL:AIF87430.1};
OS   Streptococcus agalactiae.
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
OC   Streptococcus.
OX   NCBI_TaxID=1311 {ECO:0000313|EMBL:AIF87430.1, ECO:0000313|Proteomes:UP000028184};
RN   [1] {ECO:0000313|EMBL:AIF87430.1, ECO:0000313|Proteomes:UP000028184}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NGBS061 {ECO:0000313|EMBL:AIF87430.1,
RC   ECO:0000313|Proteomes:UP000028184};
RA   Teatero S., McGeer A., Li A., Gomes J., Seah C., Demczuk W.,
RA   Martin I., Wasserscheid J., Dewar K., Melano R.G., Fittipaldi N.;
RT   "Population Structure and Antimicrobial Susceptibility of Emerging
RT   Invasive Serotype IV Group B Streptococcus in Toronto, Canada.";
RL   Submitted (AUG-2014) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:OCM71612.1, ECO:0000313|Proteomes:UP000093122}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CZ-PW-140 {ECO:0000313|EMBL:OCM71612.1,
RC   ECO:0000313|Proteomes:UP000093122};
RX   PubMed=27411639; DOI=10.1038/srep29799;
RA   Campisi E., Rinaudo C.D., Donati C., Barucco M., Torricelli G.,
RA   Edwards M.S., Baker C.J., Margarit I., Rosini R.;
RT   "Serotype IV Streptococcus agalactiae ST-452 has arisen from large
RT   genomic recombination events between CC23 and the hypervirulent CC17
RT   lineages.";
RL   Sci. Rep. 6:29799-29799(2016).
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DR   EMBL; CP007631; AIF87430.1; -; Genomic_DNA.
DR   EMBL; MAWT01000022; OCM71612.1; -; Genomic_DNA.
DR   RefSeq; WP_000176328.1; NZ_MJHP01000014.1.
DR   EnsemblBacteria; AIF87430; AIF87430; EN72_10135.
DR   EnsemblBacteria; OCM71612; OCM71612; AX245_10430.
DR   KEGG; sage:EN72_10135; -.
DR   PATRIC; fig|1311.133.peg.1968; -.
DR   KO; K01186; -.
DR   Proteomes; UP000028184; Chromosome.
DR   Proteomes; UP000093122; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004308; F:exo-alpha-sialidase activity; IEA:InterPro.
DR   InterPro; IPR026856; Sialidase_fam.
DR   InterPro; IPR011040; Sialidases.
DR   PANTHER; PTHR10628; PTHR10628; 1.
DR   Pfam; PF13088; BNR_2; 1.
DR   SUPFAM; SSF50939; SSF50939; 2.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000028184,
KW   ECO:0000313|Proteomes:UP000093122};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     12     35       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN      520    764       Sialidases. {ECO:0000259|Pfam:PF13088}.
SQ   SEQUENCE   816 AA;  92699 MW;  D6F5CE179A7E9819 CRC64;
     MTLTFGKPSI TIRRLGVITS IYMMLGFILL CGLLHPSTIY SEEIKSDINS FISIDDEKTT
     APIFDSTLDK LTNSIEERQL ELDSDTSDGL IVDDQKDKDM VVVLGDSDSQ EKLSPPLKSE
     IATEENRKQA NLAELNATQP NNRTTYIIPE SSHSIAEQQR FLIESKGSSV ALLNSDEFRK
     TAREDRGFER DKLRSLDIIP KGDLSTSNVI GNTDIASQIS LGFKKNAIQE HHLTKTFSQK
     DGKLSSVIEG MLAIGKEKVE KEIKYSGNLW QKLKAKAHCL VCCVDNLNFE DIKSYFQYYC
     HLNHQLKLPK GAILSAKTEV YRGGDFGRKN KDNVFGYRIP SLLKTEKGTL LAGADERIEQ
     ACDWGNIGMV IRRSEDDGVT WGKRETIVNL RNNPRVPLVT SGDYSGSPIN MDMALVQDTS
     SKTKRIFSIY DMFPEGRGVI SIANTPEKEY TQIGGQSYLN LYNNEKKSKV FTIRDKGIVY
     NFKGKKTDYH VITETTKSDH SNLGDIYKGK QLLGNIYFTK HKTSPFRLAK SSYVWMSYSD
     DDGRTWSSPR DITASLRRRG MKFLGIGPGK GIVLKWGPHA GRIIIPAYST NWKSHLRGSQ
     SSRLIYSDDH GKTWHTGKAV NDNRVLSNGE KIHSLTMDNK KEQNTESVPV QLKNGDIKLF
     MRNLTGNLEV ATSKDGGETW QNHVKRYKEV HDAYVQLSAI RFEHDKKEYI LLVNANGPGK
     KRQDGYARLA QVNRNGSFKW LYHHHIQDGS FAYNSVQQLN NDQFGVLYEH REKHQNSFTL
     NYKVFNWSFL SQNTEKQGTL WEKMAANWHV LFKFYL
//
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