ID A0A0E3P673_9EURY Unreviewed; 492 AA.
AC A0A0E3P673;
DT 24-JUN-2015, integrated into UniProtKB/TrEMBL.
DT 24-JUN-2015, sequence version 1.
DT 24-JAN-2024, entry version 34.
DE SubName: Full=Aldehyde dehydrogenase {ECO:0000313|EMBL:AKB29270.1};
DE EC=1.2.1.3 {ECO:0000313|EMBL:AKB29270.1};
GN ORFNames=MSSIT_2551 {ECO:0000313|EMBL:AKB29270.1};
OS Methanosarcina siciliae T4/M.
OC Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC Methanosarcinales; Methanosarcinaceae; Methanosarcina.
OX NCBI_TaxID=1434120 {ECO:0000313|EMBL:AKB29270.1, ECO:0000313|Proteomes:UP000033111};
RN [1] {ECO:0000313|EMBL:AKB29270.1, ECO:0000313|Proteomes:UP000033111}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=T4/M {ECO:0000313|EMBL:AKB29270.1,
RC ECO:0000313|Proteomes:UP000033111};
RA Henriksen J.R., Luke J., Reinhart S., Benedict M.N., Youngblut N.D.,
RA Metcalf M.E., Whitaker R.J., Metcalf W.W.;
RT "Methanogenic archaea and the global carbon cycle.";
RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the aldehyde dehydrogenase family.
CC {ECO:0000256|RuleBase:RU003345}.
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DR EMBL; CP009506; AKB29270.1; -; Genomic_DNA.
DR RefSeq; WP_048173027.1; NZ_CP009506.1.
DR AlphaFoldDB; A0A0E3P673; -.
DR GeneID; 41606638; -.
DR KEGG; msw:MSSIT_2551; -.
DR PATRIC; fig|1434120.4.peg.3351; -.
DR HOGENOM; CLU_005391_1_0_2; -.
DR OrthoDB; 6342at2157; -.
DR Proteomes; UP000033111; Chromosome.
DR GO; GO:0004029; F:aldehyde dehydrogenase (NAD+) activity; IEA:UniProtKB-EC.
DR GO; GO:0043878; F:glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity; IEA:UniProtKB-EC.
DR CDD; cd07131; ALDH_AldH-CAJ73105; 1.
DR InterPro; IPR016161; Ald_DH/histidinol_DH.
DR InterPro; IPR016163; Ald_DH_C.
DR InterPro; IPR016160; Ald_DH_CS_CYS.
DR InterPro; IPR029510; Ald_DH_CS_GLU.
DR InterPro; IPR016162; Ald_DH_N.
DR InterPro; IPR015590; Aldehyde_DH_dom.
DR PANTHER; PTHR11699:SF211; ALDEHYDE DEHYDROGENASE FAMILY 16 MEMBER A1; 1.
DR PANTHER; PTHR11699; ALDEHYDE DEHYDROGENASE-RELATED; 1.
DR Pfam; PF00171; Aldedh; 1.
DR SUPFAM; SSF53720; ALDH-like; 1.
DR PROSITE; PS00070; ALDEHYDE_DEHYDR_CYS; 1.
DR PROSITE; PS00687; ALDEHYDE_DEHYDR_GLU; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|RuleBase:RU003345,
KW ECO:0000313|EMBL:AKB29270.1}.
FT DOMAIN 17..476
FT /note="Aldehyde dehydrogenase"
FT /evidence="ECO:0000259|Pfam:PF00171"
FT REGION 1..20
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 249
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10007"
SQ SEQUENCE 492 AA; 53281 MW; 2E81E4A42A87ECBF CRC64;
MVQEYKLHIG GESKDSATGE TFDDINPATL ENLATIQVAG SVDVDRAVEA AEEGFRAWGE
VPVPRRAEVL FRAARILQER KEDLARFMTE EMGKVLPETR GDVQEAIDIA IYAAGEGRRM
FGETTTSELK DKFCMTVLRP IGVVGMITPW NFPMAIPGWK IMPALIAGNS IVFKPASDTP
LLAIKLVEIL LEAGLPPGVV NIVTGPGGST GKAIVQHPRI KAISFTGSLE TGKWIMEECA
KTMKRVSLEL GGKNPVIIMD DADLELALEG VLWGAFGTTG QRCTATSRLI LHEKIKDEFT
ARLLAKTKLL RIGNGLLPET DIGPVINKAQ LEKIERYVRI GIEEGATLLL GGKTIDSGLP
GYFFEPTVFT DVKPDMKIAQ EEIFGPVLSI ITVSGLEEAI EVANNTRYGL SSAIYTESVG
KAFRAVNKIE AGITYVNAPT IGAEVHLPFG GVKGTGNGFR EAGTEAVKEF TEVKAVYIDY
SGRLQRAQID TE
//
