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Database: UniProt/TrEMBL
Entry: A0A0E3YES0_9BURK
LinkDB: A0A0E3YES0_9BURK
Original site: A0A0E3YES0_9BURK 
ID   A0A0E3YES0_9BURK        Unreviewed;       746 AA.
AC   A0A0E3YES0;
DT   24-JUN-2015, integrated into UniProtKB/TrEMBL.
DT   24-JUN-2015, sequence version 1.
DT   07-JUN-2017, entry version 12.
DE   SubName: Full=Isocitrate dehydrogenase, NADP-dependent {ECO:0000313|EMBL:AKC71477.1};
GN   ORFNames=MB84_21455 {ECO:0000313|EMBL:AKC71477.1};
OS   Pandoraea oxalativorans.
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Pandoraea.
OX   NCBI_TaxID=573737 {ECO:0000313|EMBL:AKC71477.1, ECO:0000313|Proteomes:UP000035050};
RN   [1] {ECO:0000313|Proteomes:UP000035050}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM-23570 {ECO:0000313|Proteomes:UP000035050};
RA   Ee R., Lim Y.-L., Yong D., Yin W.-F., Chan K.-G.;
RT   "Pandoraea oxalativorans DSM 23570 Genome Sequencing.";
RL   Submitted (JUN-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC         Evidence={ECO:0000256|PIRSR:PIRSR009407-3};
CC       Name=Mn(2+); Xref=ChEBI:CHEBI:29035;
CC         Evidence={ECO:0000256|PIRSR:PIRSR009407-3};
CC       Note=Binds 1 Mg(2+) or Mn(2+) ion per subunit.
CC       {ECO:0000256|PIRSR:PIRSR009407-3};
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DR   EMBL; CP011253; AKC71477.1; -; Genomic_DNA.
DR   RefSeq; WP_046292590.1; NZ_CP011253.3.
DR   EnsemblBacteria; AKC71477; AKC71477; MB84_21455.
DR   KEGG; pox:MB84_21455; -.
DR   PATRIC; fig|573737.6.peg.45; -.
DR   KO; K00031; -.
DR   Proteomes; UP000035050; Chromosome.
DR   GO; GO:0004450; F:isocitrate dehydrogenase (NADP+) activity; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006099; P:tricarboxylic acid cycle; IEA:InterPro.
DR   InterPro; IPR004436; Isocitrate_DH_NADP_mono.
DR   Pfam; PF03971; IDH; 1.
DR   PIRSF; PIRSF009407; IDH_monmr; 1.
DR   TIGRFAMs; TIGR00178; monomer_idh; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000035050};
KW   Magnesium {ECO:0000256|PIRSR:PIRSR009407-3};
KW   Metal-binding {ECO:0000256|PIRSR:PIRSR009407-3}.
FT   REGION      134    141       Substrate binding. {ECO:0000256|PIRSR:
FT                                PIRSR009407-2}.
FT   METAL       352    352       Magnesium or manganese.
FT                                {ECO:0000256|PIRSR:PIRSR009407-3}.
FT   METAL       551    551       Magnesium or manganese.
FT                                {ECO:0000256|PIRSR:PIRSR009407-3}.
FT   METAL       555    555       Magnesium or manganese.
FT                                {ECO:0000256|PIRSR:PIRSR009407-3}.
FT   BINDING     147    147       Substrate. {ECO:0000256|PIRSR:
FT                                PIRSR009407-2}.
FT   BINDING     550    550       Substrate. {ECO:0000256|PIRSR:
FT                                PIRSR009407-2}.
FT   SITE        257    257       Critical for catalysis.
FT                                {ECO:0000256|PIRSR:PIRSR009407-1}.
FT   SITE        422    422       Critical for catalysis.
FT                                {ECO:0000256|PIRSR:PIRSR009407-1}.
SQ   SEQUENCE   746 AA;  82718 MW;  E4DEA86C9488818E CRC64;
     MSTQQPSIIY TLTDEAPLLA TGSFLPIIRT FTAPAGVTVD TSDISVSGRI LGEFPEFLTE
     EQRVPDNLAE LGRLTQDPNT NIIKLPNISA SVFQLQSAIK ELQSKGYKIP DFPEDPKTDE
     EKAIQKRYSK CLGSAVNPVL REGNSDRRAP LAVKNYAKKH PHSMGEWSMA SRTHVAHMKH
     GDFYHGEKSM TIDKARDVKM ELVTNSGKTI VLKPKVSLLD GEIIDSMFMS KKALCDFYEE
     QMEDARKTGV MFSLHVKATM MKVSHPIVFG HAVKIFYKEA FEKHGKLFDE LGVNVNNGLV
     NLYEKIEALP STQREEIIRD LHACHEHRPE LAMVDSAKGI SNLHAPNDVI VDASMPAMIR
     IGGKMWGADG RPKDTKAVIP ESTFARIYQE IINFCKTNGA FDPTTMGTVP NVGLMAQKAE
     EYGSHDKTFE IAEDGVANIV DIATGEVLLS QNVEAGDIWR MCQVKDAPIR DWVKLAVNRV
     RNSGMPAVFW LDPYRPHEAE LIKKVETYLK DYDTNGLDIQ IMSQVRAMRY TLERVIRGLD
     TISVTGNILR DYLTDLFPIM ELGTSAKMLS IVPLMAGGGM YETGAGGSAP KHVKQLVEEN
     HLRWDSLGEF LALAVSLEDL GIKTGNQRAK ILAKTLDAAT GKLLDNNKGP SPKTGELDNR
     GSQFYLSMYW AQELAEQTDD AELAKFFAPL AKQLTENEKT IVGELADVQG KPTDIGGYYK
     PDFEKLEQVM RPSKTFNAAL ASVAKA
//
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