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Database: UniProt/TrEMBL
Entry: A0A0F8XZF9_9ARCH
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Original site: A0A0F8XZF9_9ARCH 
ID   A0A0F8XZF9_9ARCH        Unreviewed;       489 AA.
AC   A0A0F8XZF9;
DT   22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT   22-JUL-2015, sequence version 1.
DT   27-SEP-2017, entry version 12.
DE   RecName: Full=Phosphoenolpyruvate carboxylase {ECO:0000256|HAMAP-Rule:MF_01904};
DE            Short=PEPC {ECO:0000256|HAMAP-Rule:MF_01904};
DE            Short=PEPCase {ECO:0000256|HAMAP-Rule:MF_01904};
DE            EC=4.1.1.31 {ECO:0000256|HAMAP-Rule:MF_01904};
GN   Name=ppcA_2 {ECO:0000313|EMBL:KKK41516.1};
GN   Synonyms=ppcA {ECO:0000256|HAMAP-Rule:MF_01904};
GN   ORFNames=Lokiarch_42400 {ECO:0000313|EMBL:KKK41516.1};
OS   Lokiarchaeum sp. GC14_75.
OC   Archaea; Asgard group; Candidatus Lokiarchaeota; Lokiarchaeum.
OX   NCBI_TaxID=1538547 {ECO:0000313|EMBL:KKK41516.1, ECO:0000313|Proteomes:UP000034722};
RN   [1] {ECO:0000313|EMBL:KKK41516.1, ECO:0000313|Proteomes:UP000034722}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=GC14-75 {ECO:0000313|EMBL:KKK41516.1};
RX   PubMed=25945739; DOI=10.1038/nature14447;
RA   Spang A., Saw J.H., Jorgensen S.L., Zaremba-Niedzwiedzka K.,
RA   Martijn J., Lind A.E., van Eijk R., Schleper C., Guy L., Ettema T.J.;
RT   "Complex archaea that bridge the gap between prokaryotes and
RT   eukaryotes.";
RL   Nature 521:173-179(2015).
CC   -!- FUNCTION: Catalyzes the irreversible beta-carboxylation of
CC       phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four-
CC       carbon dicarboxylic acid source for the tricarboxylic acid cycle.
CC       {ECO:0000256|HAMAP-Rule:MF_01904}.
CC   -!- CATALYTIC ACTIVITY: Phosphate + oxaloacetate = H(2)O +
CC       phosphoenolpyruvate + HCO(3)(-). {ECO:0000256|HAMAP-
CC       Rule:MF_01904}.
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000256|HAMAP-
CC         Rule:MF_01904};
CC   -!- SUBUNIT: Homotetramer. {ECO:0000256|HAMAP-Rule:MF_01904}.
CC   -!- SIMILARITY: Belongs to the PEPCase type 2 family.
CC       {ECO:0000256|HAMAP-Rule:MF_01904}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:KKK41516.1}.
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DR   EMBL; JYIM01000396; KKK41516.1; -; Genomic_DNA.
DR   KEGG; loki:Lokiarch_42400; -.
DR   PATRIC; fig|1538547.4.peg.4443; -.
DR   KO; K01595; -.
DR   Proteomes; UP000034722; Unassembled WGS sequence.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0008964; F:phosphoenolpyruvate carboxylase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0015977; P:carbon fixation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006107; P:oxaloacetate metabolic process; IEA:UniProtKB-UniRule.
DR   GO; GO:0006099; P:tricarboxylic acid cycle; IEA:InterPro.
DR   HAMAP; MF_01904; PEPcase_type2; 1.
DR   InterPro; IPR007566; PEP_COase_arc-type.
DR   InterPro; IPR015813; Pyrv/PenolPyrv_Kinase-like_dom.
DR   Pfam; PF14010; PEPcase_2; 1.
DR   PIRSF; PIRSF006677; UCP006677; 1.
DR   SUPFAM; SSF51621; SSF51621; 1.
DR   TIGRFAMs; TIGR02751; PEPCase_arch; 1.
PE   3: Inferred from homology;
KW   Carbon dioxide fixation {ECO:0000256|HAMAP-Rule:MF_01904};
KW   Complete proteome {ECO:0000313|Proteomes:UP000034722};
KW   Lyase {ECO:0000256|HAMAP-Rule:MF_01904};
KW   Magnesium {ECO:0000256|HAMAP-Rule:MF_01904};
KW   Pyruvate {ECO:0000313|EMBL:KKK41516.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000034722}.
SQ   SEQUENCE   489 AA;  56284 MW;  00C1FE73017FD1E0 CRC64;
     MVKNGVKIPR CMSTQHPDNV NSPFFVNNAI IGGEDEIKEA YYAFSHLGCD EQMWDCEGKE
     VDSYVVKKLL TKYKSFFSEK TLGKDLNLTL RGPNPSVERA EAKVLLEALE SIPRSFDAAR
     LFYNDDIAPI FEVILPMTAS SMEINNVYRY YSDIVVGKET KILTHGKTTI GDWIGEFKPK
     KINVIPLFED IEHMLNAHDI TRDYLQDKNL EYQRVFLARS DPALNYGLIS AVLLNKVTLQ
     RLYRLSEEIN VEIYPIIGAG SSPFRGNLRP QNVENVLEEY PSVSTFTIQS AFKYDNPPED
     VIKAINKLQK TRVKQPQEIN EERCLEIINK YLIEYQKQVV NLAPVINDVA RYVPSRRKRK
     LHIGLFGYSR NMEGIALPRA IKFTAALYSL GLPPEILGLN ALNNDDFQFV SKVYVHFEKD
     LKDSLKYLNI ESRFIPKELK EFLRDFPIYS EVDEIHKKIT EKIQDIKNSE KVNLEEYILS
     AANIRKFLG
//
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