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Database: UniProt/TrEMBL
Entry: A0A0G3EQX8_9BURK
LinkDB: A0A0G3EQX8_9BURK
Original site: A0A0G3EQX8_9BURK 
ID   A0A0G3EQX8_9BURK        Unreviewed;       746 AA.
AC   A0A0G3EQX8;
DT   16-SEP-2015, integrated into UniProtKB/TrEMBL.
DT   16-SEP-2015, sequence version 1.
DT   05-JUL-2017, entry version 15.
DE   SubName: Full=Isocitrate dehydrogenase {ECO:0000313|EMBL:AKJ69458.1};
GN   ORFNames=ABW99_15805 {ECO:0000313|EMBL:AKJ69458.1};
OS   Pandoraea thiooxydans.
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Pandoraea.
OX   NCBI_TaxID=445709 {ECO:0000313|EMBL:AKJ69458.1, ECO:0000313|Proteomes:UP000036700};
RN   [1] {ECO:0000313|Proteomes:UP000036700}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 25325 {ECO:0000313|Proteomes:UP000036700};
RA   Lim Y.L., Ee R., Yong D., How K.Y., Yin W.F., Chan K.G.;
RL   Submitted (JUN-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC         Evidence={ECO:0000256|PIRSR:PIRSR009407-3};
CC       Name=Mn(2+); Xref=ChEBI:CHEBI:29035;
CC         Evidence={ECO:0000256|PIRSR:PIRSR009407-3};
CC       Note=Binds 1 Mg(2+) or Mn(2+) ion per subunit.
CC       {ECO:0000256|PIRSR:PIRSR009407-3};
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DR   EMBL; CP011568; AKJ69458.1; -; Genomic_DNA.
DR   RefSeq; WP_047215371.1; NZ_CP014839.1.
DR   KEGG; ptx:ABW99_15805; -.
DR   PATRIC; fig|445709.3.peg.3344; -.
DR   KO; K00031; -.
DR   Proteomes; UP000036700; Chromosome.
DR   GO; GO:0004450; F:isocitrate dehydrogenase (NADP+) activity; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006099; P:tricarboxylic acid cycle; IEA:InterPro.
DR   InterPro; IPR004436; Isocitrate_DH_NADP_mono.
DR   Pfam; PF03971; IDH; 1.
DR   PIRSF; PIRSF009407; IDH_monmr; 1.
DR   TIGRFAMs; TIGR00178; monomer_idh; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000036700};
KW   Magnesium {ECO:0000256|PIRSR:PIRSR009407-3};
KW   Metal-binding {ECO:0000256|PIRSR:PIRSR009407-3};
KW   Reference proteome {ECO:0000313|Proteomes:UP000036700}.
FT   REGION      134    141       Substrate binding. {ECO:0000256|PIRSR:
FT                                PIRSR009407-2}.
FT   METAL       352    352       Magnesium or manganese.
FT                                {ECO:0000256|PIRSR:PIRSR009407-3}.
FT   METAL       551    551       Magnesium or manganese.
FT                                {ECO:0000256|PIRSR:PIRSR009407-3}.
FT   METAL       555    555       Magnesium or manganese.
FT                                {ECO:0000256|PIRSR:PIRSR009407-3}.
FT   BINDING     147    147       Substrate. {ECO:0000256|PIRSR:
FT                                PIRSR009407-2}.
FT   BINDING     550    550       Substrate. {ECO:0000256|PIRSR:
FT                                PIRSR009407-2}.
FT   SITE        257    257       Critical for catalysis.
FT                                {ECO:0000256|PIRSR:PIRSR009407-1}.
FT   SITE        422    422       Critical for catalysis.
FT                                {ECO:0000256|PIRSR:PIRSR009407-1}.
SQ   SEQUENCE   746 AA;  82374 MW;  3ABABB71145A653D CRC64;
     MSAEQSTIIY TLTDEAPLLA TSAFLPIIRT FTAPAGIQVE TSDISVAGRI LGEFPEFLTE
     EQRVPDNLAE LGRLTQLPDT NIIKLPNISA SVHQLVGAIK ELQSKGYNVP DFPEDPKTEV
     EKTIRQRYSK CLGSAVNPVL REGNSDRRAP AAVKNYARKH PHSMGEWSMA SRTHVAHMKH
     GDFYHGEKSM TLDRARDVKM ELLTADGKTI VLKPKVALQA GEIIDSMFMS KTALCEFYEE
     QMEDARKTGV MLSLHVKATM MKVSHPIVFG HAVKIFYKDA FAKHGKLFDE LGVNVNNGLV
     NLYDKIESLP SSKREEIIRD LHACHEHRPE LAMVDSAKGI SNLYAPNDVI VDASMPAMIR
     IGGKMWGADG RPKDTKAVIP ESTFARIYQE VINFCKTNGN FDPVTMGTVP NVGLMAQQAE
     EYGSHDKTFE VPEAGEARIV DIATGEVLLV QNVEQGDIWR MCQVKDAPIR DWVKLAVTRA
     RNSGMPAIFW LDPYRPHEAE LIKKVETYLK DHDTTGLDIQ IMSQVRAMRY TLERVIRGLD
     TISVTGNILR DYLTDLFPIM ELGTSAKMLS IVPLMAGGGM YETGAGGSAP KHVKQLVEEN
     HLRWDSLGEF LALAVSLEET GIKTGNARAK LLARTLDAAT GKLLENNKNP SPKTGQLDNR
     GSQFYLALYW AQALAEQTED AELAARFAPL AQQLTDNEPA IVAELSAVQG KPVDIGGYYK
     PDFAKLDAVM RPSQTFNRAL AAVNAA
//
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