GenomeNet

Database: UniProt/TrEMBL
Entry: A0A0H3ANG6_BRUO2
LinkDB: A0A0H3ANG6_BRUO2
Original site: A0A0H3ANG6_BRUO2 
ID   A0A0H3ANG6_BRUO2        Unreviewed;       272 AA.
AC   A0A0H3ANG6;
DT   16-SEP-2015, integrated into UniProtKB/TrEMBL.
DT   16-SEP-2015, sequence version 1.
DT   25-OCT-2017, entry version 17.
DE   RecName: Full=Enoyl-[acyl-carrier-protein] reductase [NADH] {ECO:0000256|PIRNR:PIRNR000094};
DE            EC=1.3.1.9 {ECO:0000256|PIRNR:PIRNR000094};
GN   Name=fabI-2 {ECO:0000313|EMBL:ABQ60373.1};
GN   OrderedLocusNames=BOV_2083 {ECO:0000313|EMBL:ABQ60373.1};
OS   Brucella ovis (strain ATCC 25840 / 63/290 / NCTC 10512).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales;
OC   Brucellaceae; Brucella.
OX   NCBI_TaxID=444178 {ECO:0000313|EMBL:ABQ60373.1, ECO:0000313|Proteomes:UP000006383};
RN   [1] {ECO:0000313|Proteomes:UP000006383}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 25840 / 63/290 / NCTC 10512
RC   {ECO:0000313|Proteomes:UP000006383};
RX   PubMed=19436743; DOI=10.1371/journal.pone.0005519;
RA   Tsolis R.M., Seshadri R., Santos R.L., Sangari F.J., Lobo J.M.,
RA   de Jong M.F., Ren Q., Myers G., Brinkac L.M., Nelson W.C., Deboy R.T.,
RA   Angiuoli S., Khouri H., Dimitrov G., Robinson J.R., Mulligan S.,
RA   Walker R.L., Elzer P.E., Hassan K.A., Paulsen I.T.;
RT   "Genome degradation in Brucella ovis corresponds with narrowing of its
RT   host range and tissue tropism.";
RL   PLoS ONE 4:E5519-E5519(2009).
CC   -!- CATALYTIC ACTIVITY: An acyl-[acyl-carrier protein] + NAD(+) = a
CC       trans-2,3-dehydroacyl-[acyl-carrier protein] + NADH.
CC       {ECO:0000256|PIRNR:PIRNR000094}.
CC   -!- SIMILARITY: Belongs to the short-chain dehydrogenases/reductases
CC       (SDR) family. FabI subfamily. {ECO:0000256|PIRNR:PIRNR000094}.
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DR   EMBL; CP000708; ABQ60373.1; -; Genomic_DNA.
DR   RefSeq; WP_002965233.1; NC_009505.1.
DR   ProteinModelPortal; A0A0H3ANG6; -.
DR   SMR; A0A0H3ANG6; -.
DR   EnsemblBacteria; ABQ60373; ABQ60373; BOV_2083.
DR   GeneID; 29594839; -.
DR   KEGG; bov:BOV_2083; -.
DR   KO; K00208; -.
DR   OMA; NHSIAWG; -.
DR   Proteomes; UP000006383; Chromosome I.
DR   GO; GO:0004318; F:enoyl-[acyl-carrier-protein] reductase (NADH) activity; IEA:UniProtKB-EC.
DR   GO; GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.
DR   InterPro; IPR014358; Enoyl-ACP_Rdtase_NADH.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR002347; SDR_fam.
DR   PANTHER; PTHR43159:SF2; PTHR43159:SF2; 1.
DR   PIRSF; PIRSF000094; Enoyl-ACP_rdct; 1.
DR   PRINTS; PR00081; GDHRDH.
DR   SUPFAM; SSF51735; SSF51735; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000006383};
KW   Fatty acid biosynthesis {ECO:0000256|PIRNR:PIRNR000094};
KW   Fatty acid metabolism {ECO:0000256|PIRNR:PIRNR000094};
KW   Lipid biosynthesis {ECO:0000256|PIRNR:PIRNR000094};
KW   Lipid metabolism {ECO:0000256|PIRNR:PIRNR000094};
KW   NAD {ECO:0000256|PIRNR:PIRNR000094};
KW   Oxidoreductase {ECO:0000256|PIRNR:PIRNR000094,
KW   ECO:0000313|EMBL:ABQ60373.1}.
FT   ACT_SITE    147    147       Proton acceptor. {ECO:0000256|PIRSR:
FT                                PIRSR000094-1}.
FT   ACT_SITE    157    157       Proton acceptor. {ECO:0000256|PIRSR:
FT                                PIRSR000094-1}.
SQ   SEQUENCE   272 AA;  29300 MW;  6DC206B38472DC31 CRC64;
     MEGLMQGKRG LIMGVANNHS LAWGIAKQLA AQGAELAFTY QGDALGKRVK PLAEQVGSDF
     VLPCDVEDIA TVDAVFEEIE KKWGGLDFLV HAIGFSDKTE LKGRYADVTT RENFSRTMVI
     SAYSFTEVAQ RAEKLMKDGG SILTLTYGGS TRTIPNYNVM GVAKAALEAM VRYLAADYGP
     QGIRVNAISA GPVRTLAGAG IGDARAIFSY QRRNSPLRRT VDIDDVGKSA VYLLSDLSSG
     VTGEIHFVDS GYNIVSMPTL EELKSSDSER GE
//
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