ID A0A0H3F9G8_RAHSY Unreviewed; 1018 AA.
AC A0A0H3F9G8;
DT 16-SEP-2015, integrated into UniProtKB/TrEMBL.
DT 16-SEP-2015, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE RecName: Full=Beta-galactosidase {ECO:0000256|ARBA:ARBA00012756, ECO:0000256|RuleBase:RU361154};
DE EC=3.2.1.23 {ECO:0000256|ARBA:ARBA00012756, ECO:0000256|RuleBase:RU361154};
DE AltName: Full=Lactase {ECO:0000256|ARBA:ARBA00032230, ECO:0000256|RuleBase:RU361154};
GN OrderedLocusNames=Rahaq_0136 {ECO:0000313|EMBL:ADW71766.1};
OS Rahnella sp. (strain Y9602).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Yersiniaceae; Rahnella.
OX NCBI_TaxID=2703885 {ECO:0000313|EMBL:ADW71766.1, ECO:0000313|Proteomes:UP000007257};
RN [1] {ECO:0000313|Proteomes:UP000007257}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Y9602 {ECO:0000313|Proteomes:UP000007257};
RG US DOE Joint Genome Institute;
RA Lucas S., Copeland A., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA Lu M., Detter J.C., Han C., Tapia R., Land M., Hauser L., Kyrpides N.,
RA Ivanova N., Ovchinnikova G., Pagani I., Sobecky P.A., Martinez R.J.,
RA Woyke T.;
RT "Complete sequence of chromosome of Rahnella sp. Y9602.";
RL Submitted (JAN-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ADW71766.1, ECO:0000313|Proteomes:UP000007257}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Y9602 {ECO:0000313|EMBL:ADW71766.1,
RC ECO:0000313|Proteomes:UP000007257};
RX PubMed=22461551; DOI=10.1128/JB.00095-12;
RA Martinez R.J., Bruce D., Detter C., Goodwin L.A., Han J., Han C.S.,
RA Held B., Land M.L., Mikhailova N., Nolan M., Pennacchio L., Pitluck S.,
RA Tapia R., Woyke T., Sobecky P.A.;
RT "Complete Genome Sequence of Rahnella sp. Strain Y9602, a
RT Gammaproteobacterium Isolate from Metal- and Radionuclide-Contaminated
RT Soil.";
RL J. Bacteriol. 194:2113-2114(2012).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Hydrolysis of terminal non-reducing beta-D-galactose residues
CC in beta-D-galactosides.; EC=3.2.1.23;
CC Evidence={ECO:0000256|ARBA:ARBA00001412,
CC ECO:0000256|RuleBase:RU361154};
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 2 family.
CC {ECO:0000256|ARBA:ARBA00007401, ECO:0000256|RuleBase:RU361154}.
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DR EMBL; CP002505; ADW71766.1; -; Genomic_DNA.
DR RefSeq; WP_013573484.1; NC_015061.1.
DR AlphaFoldDB; A0A0H3F9G8; -.
DR KEGG; rah:Rahaq_0136; -.
DR eggNOG; COG3250; Bacteria.
DR HOGENOM; CLU_002346_0_2_6; -.
DR OrthoDB; 9758603at2; -.
DR Proteomes; UP000007257; Chromosome.
DR GO; GO:0009341; C:beta-galactosidase complex; IEA:InterPro.
DR GO; GO:0004565; F:beta-galactosidase activity; IEA:UniProtKB-EC.
DR GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR GO; GO:1901575; P:organic substance catabolic process; IEA:UniProt.
DR Gene3D; 2.70.98.10; -; 1.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 2.
DR InterPro; IPR004199; B-gal_small/dom_5.
DR InterPro; IPR036156; Beta-gal/glucu_dom_sf.
DR InterPro; IPR011013; Gal_mutarotase_sf_dom.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR014718; GH-type_carb-bd.
DR InterPro; IPR006101; Glyco_hydro_2.
DR InterPro; IPR023232; Glyco_hydro_2_AS.
DR InterPro; IPR006103; Glyco_hydro_2_cat.
DR InterPro; IPR023230; Glyco_hydro_2_CS.
DR InterPro; IPR006102; Glyco_hydro_2_Ig-like.
DR InterPro; IPR006104; Glyco_hydro_2_N.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR032312; LacZ_4.
DR PANTHER; PTHR46323; BETA-GALACTOSIDASE; 1.
DR PANTHER; PTHR46323:SF2; BETA-GALACTOSIDASE; 1.
DR Pfam; PF02929; Bgal_small_N; 1.
DR Pfam; PF00703; Glyco_hydro_2; 1.
DR Pfam; PF02836; Glyco_hydro_2_C; 1.
DR Pfam; PF02837; Glyco_hydro_2_N; 1.
DR Pfam; PF16353; LacZ_4; 1.
DR PRINTS; PR00132; GLHYDRLASE2.
DR SMART; SM01038; Bgal_small_N; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF49303; beta-Galactosidase/glucuronidase domain; 2.
DR SUPFAM; SSF74650; Galactose mutarotase-like; 1.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
DR PROSITE; PS00719; GLYCOSYL_HYDROL_F2_1; 1.
DR PROSITE; PS00608; GLYCOSYL_HYDROL_F2_2; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295, ECO:0000256|RuleBase:RU361154};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU361154}.
FT DOMAIN 724..995
FT /note="Beta galactosidase small chain/"
FT /evidence="ECO:0000259|SMART:SM01038"
SQ SEQUENCE 1018 AA; 116584 MW; 43F2AD5859099FB1 CRC64;
MNNWENIEKQ SENRLPPRAS FFSYENPQAA LRFDRAASHG FQLLSGRWQF RFFEHPALVP
DEFYNQPMTE WGHITVPGMW QMEGHGQLQY TDEGFPFPID VPYVPTNNPT GAYQQRFTLD
AAWTGKQTLI KFDGVETYFE VYVNGHYVGF SKGSRLCAEF DISASVKPGE NLLSVRVLQW
ADSTYIEDQD MWWMAGIFRD VYLIGQDPVH LNDFTVVTTF DENYCDAVLN IDAVLRNLLQ
PVSGYRLHAQ LFDDGVCVAQ LSADNLNIGD ETRCRLDIPV SHPRQWNAEH PELYQLLLTL
YDDTGQMISV VPQRVGFRDI RVRDGLFYVN GRYLKLHGVN RHDHDHRKGR AVDMARVERD
IILMKQHNIN AVRTAHYPND PRFYELCDIY GLFVMAETDL ESHGFANVGD LSRISDDPHW
EHAYVERIGR HVMAQKNHPS IIMWSLGNES GYGCNIRAMA KHCKALDPTR LVHYEEDRDA
EVTDVISTMY SRVQMMNAFG EYPHAKPRII CEYAHAMGNG PGGLAEYQAV LNRHDSLQGH
YIWEWCDHGL LETGENGQMR YTYGGDYGDY PNNYNFCMDG LIYPDQTPGP GLREYKQVLC
PVGVSLRGGA LHIKNRYWFS SLEDITLSLT VQVAGRGLET REISLPHLQP GEGETLALPE
FPASGQEVFL NVGIRKNSPT VYSEAQHPLG QYQMLLQAAR PSAMKPAPQK SATLLCDEQK
HQLIVSGEGF RLAFSRLDGE LQSWQVDDEE ITGRAPKLNF FKPVIDNHKQ EFEGLWQPHH
LHIMQQHFRQ MHWARQQDDV VIEVQSIIAP PVFDFGMRCT YRWQISPQGA VTLDLSGSPY
GNFDSIIPKI GLDFGVSRRF TQVEYYGRGP DENYQDSCQA NLIGHYQQPV SRLFENYPMP
QDNGNRQDMR WLSLCDDAGK GIFIQPRQPL NFSLWPYSAQ MLQQAQHIDE LTPDGCLTLN
LDHKISGLGS NSWGSEVLDS YRVYFSAFRY GFTMVPFSQH DTNSQQLAEF TFHPAEEN
//
