GenomeNet

Database: UniProt/TrEMBL
Entry: A0A0H4XE87_9DELT
LinkDB: A0A0H4XE87_9DELT
Original site: A0A0H4XE87_9DELT 
ID   A0A0H4XE87_9DELT        Unreviewed;      5723 AA.
AC   A0A0H4XE87;
DT   14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT   14-OCT-2015, sequence version 1.
DT   25-OCT-2017, entry version 16.
DE   SubName: Full=Non-ribosomal peptide synthetase {ECO:0000313|EMBL:AKQ66397.1};
GN   ORFNames=A176_003309 {ECO:0000313|EMBL:AKQ66397.1};
OS   Myxococcus hansupus.
OC   Bacteria; Proteobacteria; Deltaproteobacteria; Myxococcales;
OC   Cystobacterineae; Myxococcaceae; Myxococcus.
OX   NCBI_TaxID=1297742 {ECO:0000313|EMBL:AKQ66397.1, ECO:0000313|Proteomes:UP000009026};
RN   [1] {ECO:0000313|Proteomes:UP000009026}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=contaminant ex DSM 436 {ECO:0000313|Proteomes:UP000009026};
RA   Subramanian S., Sharma G.;
RL   Submitted (JUN-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation
CC       of feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00258}.
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DR   EMBL; CP012109; AKQ66397.1; -; Genomic_DNA.
DR   EnsemblBacteria; AKQ66397; AKQ66397; A176_003309.
DR   KEGG; mym:A176_003309; -.
DR   PATRIC; fig|1297742.4.peg.3337; -.
DR   Proteomes; UP000009026; Chromosome.
DR   GO; GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.
DR   GO; GO:0031177; F:phosphopantetheine binding; IEA:InterPro.
DR   Gene3D; 1.10.1200.10; -; 5.
DR   Gene3D; 3.20.20.30; -; 1.
DR   InterPro; IPR010071; AA_adenyl_domain.
DR   InterPro; IPR036736; ACP-like_sf.
DR   InterPro; IPR025110; AMP-bd_C.
DR   InterPro; IPR020845; AMP-binding_CS.
DR   InterPro; IPR000873; AMP-dep_Synth/Lig.
DR   InterPro; IPR024011; Biosynth_lucif-like_mOase_dom.
DR   InterPro; IPR001242; Condensatn.
DR   InterPro; IPR011251; Luciferase-like_dom.
DR   InterPro; IPR036661; Luciferase-like_sf.
DR   InterPro; IPR020806; PKS_PP-bd.
DR   InterPro; IPR009081; PP-bd_ACP.
DR   InterPro; IPR006162; Ppantetheine_attach_site.
DR   Pfam; PF00501; AMP-binding; 6.
DR   Pfam; PF13193; AMP-binding_C; 4.
DR   Pfam; PF00296; Bac_luciferase; 1.
DR   Pfam; PF00668; Condensation; 5.
DR   Pfam; PF00550; PP-binding; 5.
DR   SMART; SM00823; PKS_PP; 5.
DR   SUPFAM; SSF47336; SSF47336; 5.
DR   SUPFAM; SSF51679; SSF51679; 1.
DR   TIGRFAMs; TIGR01733; AA-adenyl-dom; 3.
DR   TIGRFAMs; TIGR04020; seco_metab_LLM; 1.
DR   PROSITE; PS50075; ACP_DOMAIN; 5.
DR   PROSITE; PS00455; AMP_BINDING; 5.
DR   PROSITE; PS00012; PHOSPHOPANTETHEINE; 5.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000009026}.
FT   DOMAIN      598    670       Carrier. {ECO:0000259|PROSITE:PS50075}.
FT   DOMAIN     2021   2088       Carrier. {ECO:0000259|PROSITE:PS50075}.
FT   DOMAIN     3081   3147       Carrier. {ECO:0000259|PROSITE:PS50075}.
FT   DOMAIN     4561   4628       Carrier. {ECO:0000259|PROSITE:PS50075}.
FT   DOMAIN     5617   5685       Carrier. {ECO:0000259|PROSITE:PS50075}.
FT   MOD_RES    5650   5650       O-(pantetheine 4'-phosphoryl)serine.
FT                                {ECO:0000256|PROSITE-ProRule:PRU00258}.
SQ   SEQUENCE   5723 AA;  621705 MW;  EEE3684A5390DF2D CRC64;
     MRPPSAVTLM ELLEARTQSL GDTRLYTFLE DGGDDESLSY AGLDLRARRI GAALQALAQA
     GERAVLLYPP GLEYVAGFFG CLYGGLIAVP AYPPDPTRLD RTLPRLRAII RDARATVVLT
     TAFILEMGEG LFEGAPELAA LRWVATDSLP EGTEEGWRRP SPTRDTLAFL QYTSGSTGDP
     KGVLLSNGNL LHNLGLISHA FEVHSDSVGV IWLPPYHDMG LIGGILQPLY AGFPVALMSP
     LAFLRRPRFW LESLSRFGGT VSGGPCFAFD LCVRKVPPSE REGLDLSRWE LAFCGAEPIR
     PEVMLRFSEA FAPVGFKGGA LYPCYGLAEG TLIASGGQKG AGVLTRTWDS EALERNEALE
     AVGGPGARPL VGCGQTLPDQ SLLVVDPEMR LPCPPERVGE IWVSGPSVAL GYWERPEESE
     AAFGARLADS EEGPRFLRTG DLGLMRDGEL FVVGRRKDLI ILRGRNLHPQ DLELTVERSH
     AALRPGCGAA FSIDVGGEER LAVVYEVDAR KPWTAEDVVG AVRRGLSEAH EVQLHTLVLI
     EPGALPKTSS GKIQRRACRA ELLAGTSRSV LNWRESDSSP STQMEAVRVP GEDSTPVTVE
     ALEAWLLSRV AARLRTSPDE LARDVPITSL GLDSLGAVEL ANDIEALGSV FRMEALLHGP
     TVAELARTLF SARGGASGPA LVRGEAGVAA PLSLAQQRLW LFEQLERGSP AYHLPAAVRL
     TGPLDAKALE RAFAEILQRH EALRMSLRED DGTPGQVAAP VPTPVLRWVD LRDTLAADQE
     ASALKLAHDE ARAPFDLVLG PLLRGTVFQL GAQEHLLVVV MHHIASDGAS FGILARELSA
     LYGGQAALAP LAFQYADFAR WRRAQEADGA WASSLDWWKA HLAGTPTALE LPADRLRPPT
     PSYRGGRVSL QLPELLTAKL EALGRSEGAT LFMTLLAAFE VLLARHSGQT DFCVGTAVNG
     RERTGLEGLM GCFLDLVVLR ASVAGAPRFR ELLAQTRRTV LDAFAHRDVP FEQVVETVQP
     ARDRARAPLF QVLFVLQPEP GAGLSLPGLE ARRVEVDPGA TPYDLTLSLA RGAEGVGGWL
     EYATDLFDAA TAERLVARLR VLLEAVAADP EQPISTLPLL PEAERQRMLV DWNDTRTEAP
     DACIHALVAA QVARTPDAVA VVCGAASLTY RELDQRANAV AWRLREQGVG PECVVGLCAD
     RSVDLVVGLL GILKAGGAYL PLDPSYPEAR LSLMLEDSGA SVVLVHRHLA GALPFGGRTV
     VLLDTSEGRA SAAEAPSTAV GPENLAYVLY TSGSTGRPKG VLIPHRNVAN FFTGMDGRVG
     ATPGTWLSVT SVSFDISVLE LLWTLARGFK VVVQGEQGAL GAASRRPVRS RKKPLGFSLF
     YFAADEGAAG AERYRLLLEG ARFADRHGFE AVWTPERHLH AFGGLYPNPS VTGAAIAAIT
     ERVAIRAGSV VLPLHHPVRV AEEWSLVDNL SKGRVGISVA PGWHANDFVL APDNYADRRE
     RSRQDLDTVR RLWRGETLRF PNGAGSPVDV RLRPSPVQKE LPVWLTAAGN PDTFREAGRL
     GAGVLTHLLG QRWEELEERI ALYREAWREA GHAGEGHVTL MLHTFVGHDV ERVREVVEGP
     LRRYLSDSAD LMRGLGRTLG VDLDPSSVRP EDLDALVERA FGRFFEGAGL FGTPRTCREQ
     VARIEALGVD EVACLVDFGV DADAVLASLP ALDAVRQRCE RDFHLQSDGG DSVPAQLRKQ
     AVTHLQCTPS LAQALLLEPG AQGALSGLER LLVGGEALPA ELAARLRDTV GGALLNMYGP
     TETTIWSSTH TVDGVSGAVP IGTPIANTSL YVLDDVLRPV PIGVPGELYI GGAGVARGYH
     ARPELTAERF LPEPWGSQAG ARMYRTGDRV RWRADGTVEF LGRADDQVKV RGFRVEPGEV
     ESALVRHPDV SQAVVVARED VPGSARLVAY VVSRSPAGVP VEALRDFARR SLPEHLVPSA
     VVTLEALPLT PNGKVDRKAL PAPEAAIDVA RREYVAPRTE TEQRVAELWA TLLGMERVSA
     NDDFFALGGH SLLATRAASR IREAFGVDLP LRELFESATP AALGARIDAR LLGASRVPPL
     VARTHSGALP LSFAQQRLWF LEQLEPGGAA YNDSVAVRVE GALDVAVLER CLREVVQRHD
     VLRATFHDDS GTPSWRINAV EQLRLEQVDL SALAGEAQST ALATHLGKAS LRAFDLASGP
     PLRASLVRLS SREQVLLLVL HHLVTDGASM GVLVREVAVL YRAFAKGQPS PLAELPLQYV
     DYSAWQRDWL RGDALDAQLT YWRQRLDGAP RVLELPTDHP RPAVRSSRGT NRSMLLGSEL
     SLALKSLALR EGATPFMVLL AGFSALLSRH SGQSDLCVGT PVAGRDRTEL EGLIGCFVNT
     LVLRVSLEGT PSFRELIGRA RETVLGAFAH QDAPFEELVK ALQPERDLSR SPLFQAMLVM
     QEDPLPEMSV PGVRLSVQPQ PSHTAKFDLR LIFTDTPEGY SANLELSSDL FDADTASRLL
     AHLRELLTAG VREPEQAIVD LPLMPPEERH RVLVTWNDTL KSRAEPQVLH RLIEAQVDRT
     PDAVAVSFEG ETLSYRELDG RANQLARYLR ARGVGPDVRV AMCAERSLEM VVGLLGILKA
     GGAYVPLDPE YPRERLEYML TDASAPVLLT QARLADGMPR GGATVVCLDS EWEGVAREHT
     ERLDVRVQPQ GLAYVIYTSG STGRPKGAMN THAAVCNRLL WMQEAYGLDA SDRVLQKTPF
     SFDVSVWEFF WPLMTGARLV MARPGGHREP AYLTDTVSRE RITTLHFVPS MLRPFLEELD
     LVSSCAGLRR VFCSGEALPA DLRDRFFTVP RAELHNLYGP TEAAVDVTAW ACAREDRRPL
     VPIGRPIANA RMYVLDERLR PVPPGVPGEL FISGEPLARG YWQRPSLTAE RFLPDTVAAV
     PGARMYRTGD KARFLADGAL EYLGRLDDQV KVRGFRIELG EIEAVLSQHA GVRAAAVAVR
     EDIPGDRRLV AYVVATSEGE VSELRDFLGT RLPEHMLPSA FVTLEALPLS PSGKLDRRAL
     PAPERSTLGA GDSYVAPRNA LEQQLARIWA DVLGVERVGT EARFFELGGD SILALQVIAR
     ARQAGIHLTA RQVFQHPTVA GLAQVAASAR RLGEQGPVMG PVPLTPIQTW FVERDLPEAH
     HFNQALLLEP REPLNAEMLS AALRALVDHH DALRLRLTRS TAGWEQSCAE PGRDVPLRQV
     DLAGLTPAAQ ASEMERLATE AQAGLDLADG RLVRAVLFDR GAGQTGRLLL VIHHLAVDGV
     SWRILLEDLE TALGQLGRGG AVALPAKSTS FQAWARRLEE YAASPALTEE LAFWRKAPDS
     DVARLPVDFP AGVNSQGSER VVTSVLDADV TRALLRSAAA GRHTSLEDVL LAGVSRSLAR
     WSGARRLRID LESHGRDELF DDVDLSRTVG WFTALFPVRL DLSKGADAAA VLAEVHAARE
     RRQGRGIGFG LLRYLRRDST VAPASEVLFN YLGQVDAGSR ASALFSLASE STGAAQGTRG
     PRSHVLEVVA RVVQGRLELS WRFSDALHSR ETIDALARGC VETLTELARP TEERYPLSSL
     QHGLLFQVLL EPGTDAYFEQ RSWTLSGPVD VRALRGAWDA VVERHPALRT SFLWEGLDTP
     LQVVGSRITL PWSEHDWRGL PSEDAQAQAL ETFLREDRVR GFELSRAPLM RVALLRLKDD
     AWRFVWSFHH LLLDGWSLAR VLGEVLEAYS VLVRGGEWRP GPVTDFRAYV EWLGHQQPER
     DAAFWRELLE GVEAPTLLPA EGGVKGARDT GEQALELGDA DTAVLQELAR RHGVTPSTWV
     HGAWAMVLSR YGGGADAVFG TTLAGRPPEL PGIEEAVGLF IHTLPVRTRV RSTVALLAWL
     RELQGLLVDL GQREHVPLTR LQEWSDIPRG VPLFESLLVF ENYPVDAALG RGAAGLELKD
     FGAFERTHYP LTAVAVPGRS LRLKVLYRRE RIGDDAAATL VAHWRGLLRT MMARPEQRLG
     DVPVLSEAER RRVLLEWNAT ETAYPREATV HGLFKAQAAR TPSAIAVDHG GTTLTYAELD
     ARAEQVASRL LRLGVQRGST VGLCVERSAE LVVGMLGILK AGAAYVPLDP AYPRERLAWM
     LSDSGARVLV TQERLRATLP SDGVRVLSLD QVSVGEGDGA HVPLTPVSGA EDAAYVIYTS
     GSTGTPKGVC VPHRAVVRLV VETDFIRVVP EDRVAQASNA SFDAATFEVW GALLNGARLV
     GVDRDTALSP RAFANWLKDA GIRVLFLTTA WFNQVVGEAP EAFGGLRQLH FGGEAVDPRP
     VRRVLREGPP ERLLHVYGPT ENTTFSTWHL ITDVPEDAAG IPIGRPLANT VQYVLDDAMA
     PVPPGGVGEL WLGGDGLAWG YLGRPDLTAE RFTPNPFSPR PGARLYRTGD RVRLLPDGAV
     TFVGRVDTQV KVRGFRVEPG EVEAALLRHP GVGQAVVLAR EDAVGGSRRL VAYAVPSGVA
     NAPLAASALR GFLVEHLPAY MVPSAITVLE RLPLTPNGKV DRRALPEPTL EVETLAPRGP
     EEALLAGLFG ELLGVPRVGA DDSFFDLGGH SLLATRVVTR IHATFGVALP LRDLFEEPTV
     ARLAERIRQA RVSSTWVRPP PIVPVSRERP LPLSAMQERL WLLEQLQPGT ALYTVPWAAW
     LSGPLDVPVL ERALAALARR HEALRTTFSS NAGAPVQVIH PNLALPLSVV DLRGVPEGEA
     QALRAAADEV RRPFDLVQGP LFRALLIRTA EDAHLLVLTL HHIISDGWSL GVAVRELTAL
     YGAELHGRAS PLPEPFLQPA DHAVWQREWL QGEALTDQVG YWRKQLAGAP PVLELPKDFA
     RPSLQRFRGD TVAVAIPSEL SQSFRALCVR EGVTPFMGLL AAFQLLLSRV SGQEDVCVGS
     PIAGRQQPGL ENLIGFFVNT LVLRSRLPRS LTFRELLHQV RETTLDAYAR QDVPFEKLVE
     ALQPPRSLSH APLIQVVLAL HEGTRRDAAP EGLTLRPVEL ASGTAKFDLT LSLADTAEGF
     SGTLEFDADL FTRETATRWM HGLQVLMRSA VADAGQALGA LPMMDAAERQ QLLVTWNDTA
     ANYPREACLA ELFEAQAARS PDAIALECED ARLTYAELDR RANQLAWYLR KRGVAPGMPV
     GLCLHRSIDL VVGMLGILKA GGAYVPLDPA YPKERLAFMV EDTRLSVVLA QQTVLALLPT
     GSAEVVLLDS AWDDVSREPE SAPKVSVPAE SLSYVMYTSG STGQPKGVCV PQRAVARLVL
     GSRFARWGAD EVFLQLAPIC FDASTFELWG ALLHGAKLVL FPPRTPTVDA LKDVLTRHGV
     TTLWLTAALF EALSAARPDA LDGVRQLLVG GDVLPPASVR ERLARGGVLV NGYGPTEGTT
     FTCCHVMEGT IAEGAIPIGR PIANTRVYVV DAGLRPVPVG VPGELLIAGD GLAWGYLGRA
     ELTAERFIPD PFGPETGARL YRTGDRVRYR EDGTLEFLER LDAQVKVRGY RVEPGEVEEA
     LRKHQSVAEA VVVARPDPAG GKRLVAYAVP RAGTTLEPRE LRAFLAGSLP EFMVPSALVP
     LTALPLTPVG KVDRSALPEP EVARLAGSTF TEPTSALERQ VAVLWAKVLG VERVGVEDHF
     FADLGGSSMS VVKACALLRD ELKRDVPATR FFEHPTVRAF VMSLERDGEA AAETQDNEAH
     VDRAQQRRQA IRRQGRRGNH GND
//
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