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Database: UniProt/TrEMBL
Entry: A0A0H6P4D5_VIBCL
LinkDB: A0A0H6P4D5_VIBCL
Original site: A0A0H6P4D5_VIBCL 
ID   A0A0H6P4D5_VIBCL        Unreviewed;       171 AA.
AC   A0A0H6P4D5;
DT   14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT   14-OCT-2015, sequence version 1.
DT   31-JAN-2018, entry version 25.
DE   RecName: Full=Superoxide dismutase [Cu-Zn] {ECO:0000256|RuleBase:RU000393};
DE            EC=1.15.1.1 {ECO:0000256|RuleBase:RU000393};
GN   Name=sodC {ECO:0000313|EMBL:CSC15176.1};
GN   ORFNames=BTY66_04480 {ECO:0000313|EMBL:OQM91434.1}, CSW01_07945
GN   {ECO:0000313|EMBL:ATQ46626.1}, EN12_07685
GN   {ECO:0000313|EMBL:AKO75120.1}, ERS013173_01917
GN   {ECO:0000313|EMBL:CSA85931.1}, ERS013202_02184
GN   {ECO:0000313|EMBL:CSC15176.1};
OS   Vibrio cholerae.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales;
OC   Vibrionaceae; Vibrio.
OX   NCBI_TaxID=666 {ECO:0000313|EMBL:CSC15176.1, ECO:0000313|Proteomes:UP000043247};
RN   [1] {ECO:0000313|EMBL:AKO75120.1, ECO:0000313|Proteomes:UP000036184}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=TSY216 {ECO:0000313|EMBL:AKO75120.1,
RC   ECO:0000313|Proteomes:UP000036184};
RX   PubMed=26079534; DOI=10.3201/eid2107.141055;
RA   Okada K., Natakuathung W., Na-Ubol M., Roobthaisong A., Wongboot W.,
RA   Maruyama F., Nakagawa I., Chantaroj S., Hamada S.;
RT   "Characterization of 3 Megabase-Sized Circular Replicons from Vibrio
RT   cholerae.";
RL   Emerg. Infect. Dis. 21:1262-1263(2015).
RN   [2] {ECO:0000313|EMBL:CSC15176.1, ECO:0000313|Proteomes:UP000039886, ECO:0000313|Proteomes:UP000043247}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=A109 {ECO:0000313|EMBL:CSA85931.1,
RC   ECO:0000313|Proteomes:UP000039886}, A346
RC   {ECO:0000313|EMBL:CSC15176.1}, and A346(2)
RC   {ECO:0000313|Proteomes:UP000043247};
RA   Informatics Pathogen;
RL   Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
RN   [3] {ECO:0000313|EMBL:OQM91434.1, ECO:0000313|Proteomes:UP000192124}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=7714 {ECO:0000313|EMBL:OQM91434.1,
RC   ECO:0000313|Proteomes:UP000192124};
RX   PubMed=28219321;
RA   Kachwamba Y., Mohammed A.A., Lukupulo H., Urio L., Majigo M.,
RA   Mosha F., Matonya M., Kishimba R., Mghamba J., Lusekelo J., Nyanga S.,
RA   Almeida M., Li S., Domman D., Massele S.Y., Stine O.C.;
RT   "Genetic Characterization of Vibrio cholerae O1 isolates from
RT   outbreaks between 2011 and 2015 in Tanzania.";
RL   BMC Infect. Dis. 17:157-157(2017).
RN   [4] {ECO:0000313|EMBL:ATQ46626.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=E7946 {ECO:0000313|EMBL:ATQ46626.1};
RA   Banno H., Chua N.-H.;
RL   Submitted (OCT-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Destroys radicals which are normally produced within the
CC       cells and which are toxic to biological systems.
CC       {ECO:0000256|RuleBase:RU000393}.
CC   -!- CATALYTIC ACTIVITY: 2 superoxide + 2 H(+) = O(2) + H(2)O(2).
CC       {ECO:0000256|RuleBase:RU000393}.
CC   -!- COFACTOR:
CC       Name=Cu cation; Xref=ChEBI:CHEBI:23378;
CC         Evidence={ECO:0000256|RuleBase:RU000393};
CC       Note=Binds 1 copper ion per subunit.
CC       {ECO:0000256|RuleBase:RU000393};
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000256|RuleBase:RU000393};
CC       Note=Binds 1 zinc ion per subunit.
CC       {ECO:0000256|RuleBase:RU000393};
CC   -!- SIMILARITY: Belongs to the Cu-Zn superoxide dismutase family.
CC       {ECO:0000256|RuleBase:RU000393}.
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DR   EMBL; CP007653; AKO75120.1; -; Genomic_DNA.
DR   EMBL; CP024162; ATQ46626.1; -; Genomic_DNA.
DR   EMBL; CWPD01000008; CSA85931.1; -; Genomic_DNA.
DR   EMBL; CWQG01000008; CSC15176.1; -; Genomic_DNA.
DR   EMBL; MSEO01000003; OQM91434.1; -; Genomic_DNA.
DR   RefSeq; WP_001071442.1; NZ_NMTD01000009.1.
DR   EnsemblBacteria; AKO75120; AKO75120; EN12_07685.
DR   EnsemblBacteria; CSA85931; CSA85931; ERS013173_01917.
DR   EnsemblBacteria; CSC15176; CSC15176; ERS013202_02184.
DR   KEGG; vcq:EN18_11095; -.
DR   PATRIC; fig|666.1969.peg.2912; -.
DR   KO; K04565; -.
DR   Proteomes; UP000036184; Chromosome 1.
DR   Proteomes; UP000039886; Unassembled WGS sequence.
DR   Proteomes; UP000043247; Unassembled WGS sequence.
DR   Proteomes; UP000192124; Unassembled WGS sequence.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004784; F:superoxide dismutase activity; IEA:UniProtKB-EC.
DR   CDD; cd00305; Cu-Zn_Superoxide_Dismutase; 1.
DR   Gene3D; 2.60.40.200; -; 1.
DR   InterPro; IPR036423; SOD-like_Cu/Zn_dom_sf.
DR   InterPro; IPR024134; SOD_Cu/Zn_/chaperone.
DR   InterPro; IPR018152; SOD_Cu/Zn_BS.
DR   InterPro; IPR001424; SOD_Cu_Zn_dom.
DR   PANTHER; PTHR10003; PTHR10003; 1.
DR   Pfam; PF00080; Sod_Cu; 1.
DR   SUPFAM; SSF49329; SSF49329; 1.
DR   PROSITE; PS00087; SOD_CU_ZN_1; 1.
DR   PROSITE; PS00332; SOD_CU_ZN_2; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000036184,
KW   ECO:0000313|Proteomes:UP000039886, ECO:0000313|Proteomes:UP000043247,
KW   ECO:0000313|Proteomes:UP000192124};
KW   Copper {ECO:0000256|RuleBase:RU000393};
KW   Metal-binding {ECO:0000256|RuleBase:RU000393};
KW   Oxidoreductase {ECO:0000256|RuleBase:RU000393,
KW   ECO:0000313|EMBL:CSC15176.1}; Signal {ECO:0000256|SAM:SignalP};
KW   Zinc {ECO:0000256|RuleBase:RU000393}.
FT   SIGNAL        1     19       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        20    171       Superoxide dismutase [Cu-Zn].
FT                                {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5011854372.
FT   DOMAIN       31    169       Sod_Cu. {ECO:0000259|Pfam:PF00080}.
SQ   SEQUENCE   171 AA;  17697 MW;  7483250CE4266C79 CRC64;
     MNQFTLFAVV AFFSSSVLAQ EMTVVMTDLS SGQSVGTVTV TDSEYGTVFT PQLTGLPAGL
     HGFHVHANGS CETSSKDGKT VLGGAAGGHY DPQNTGKHGY PWTNDNHLGD LPALYVDAQG
     QANQPVLASR FKMAEVKGKA LMVHAGGDNH SDHPMPLGGG GARIVCGVIG L
//
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