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Database: UniProt/TrEMBL
Entry: A0A0J8TJY9_ACIBA
LinkDB: A0A0J8TJY9_ACIBA
Original site: A0A0J8TJY9_ACIBA 
ID   A0A0J8TJY9_ACIBA        Unreviewed;       745 AA.
AC   A0A0J8TJY9;
DT   14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT   14-OCT-2015, sequence version 1.
DT   25-OCT-2017, entry version 15.
DE   SubName: Full=Isocitrate dehydrogenase, NADP-dependent {ECO:0000313|EMBL:KMV08665.1};
DE            EC=1.1.1.42 {ECO:0000313|EMBL:KMV08665.1};
GN   ORFNames=AB895_0490 {ECO:0000313|EMBL:KMV08665.1}, CAT05_16870
GN   {ECO:0000313|EMBL:OTS33782.1};
OS   Acinetobacter baumannii.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Moraxellaceae; Acinetobacter;
OC   Acinetobacter calcoaceticus/baumannii complex.
OX   NCBI_TaxID=470 {ECO:0000313|EMBL:KMV08665.1, ECO:0000313|Proteomes:UP000036720};
RN   [1] {ECO:0000313|EMBL:KMV08665.1, ECO:0000313|Proteomes:UP000036720}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=B8342 {ECO:0000313|EMBL:KMV08665.1,
RC   ECO:0000313|Proteomes:UP000036720};
RA   Vijaykumar S., Balaji V., Biswas I.;
RT   "Complete genome sequence of Acinetobacter baumannii strain B8342, a
RT   motility positive clinical isolate.";
RL   Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:OTS33782.1, ECO:0000313|Proteomes:UP000195046}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ARLG1800 {ECO:0000313|EMBL:OTS33782.1,
RC   ECO:0000313|Proteomes:UP000195046};
RA   Song R., Chenine A.L., Ruprecht R.M.;
RL   Submitted (MAY-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC         Evidence={ECO:0000256|PIRSR:PIRSR009407-3};
CC       Name=Mn(2+); Xref=ChEBI:CHEBI:29035;
CC         Evidence={ECO:0000256|PIRSR:PIRSR009407-3};
CC       Note=Binds 1 Mg(2+) or Mn(2+) ion per subunit.
CC       {ECO:0000256|PIRSR:PIRSR009407-3};
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:KMV08665.1}.
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DR   EMBL; LFYZ01000001; KMV08665.1; -; Genomic_DNA.
DR   EMBL; NGGR01000056; OTS33782.1; -; Genomic_DNA.
DR   RefSeq; WP_000896678.1; NZ_NGIK01000017.1.
DR   EnsemblBacteria; KMV08665; KMV08665; AB895_0490.
DR   KEGG; abaa:IX88_15600; -.
DR   PATRIC; fig|470.1294.peg.3072; -.
DR   KO; K00031; -.
DR   Proteomes; UP000036720; Unassembled WGS sequence.
DR   Proteomes; UP000195046; Unassembled WGS sequence.
DR   GO; GO:0004450; F:isocitrate dehydrogenase (NADP+) activity; IEA:UniProtKB-EC.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006099; P:tricarboxylic acid cycle; IEA:InterPro.
DR   InterPro; IPR004436; Isocitrate_DH_NADP_mono.
DR   Pfam; PF03971; IDH; 1.
DR   PIRSF; PIRSF009407; IDH_monmr; 1.
DR   TIGRFAMs; TIGR00178; monomer_idh; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000036720,
KW   ECO:0000313|Proteomes:UP000195046};
KW   Magnesium {ECO:0000256|PIRSR:PIRSR009407-3};
KW   Metal-binding {ECO:0000256|PIRSR:PIRSR009407-3};
KW   Oxidoreductase {ECO:0000313|EMBL:KMV08665.1}.
FT   REGION      134    141       Substrate binding. {ECO:0000256|PIRSR:
FT                                PIRSR009407-2}.
FT   METAL       352    352       Magnesium or manganese.
FT                                {ECO:0000256|PIRSR:PIRSR009407-3}.
FT   METAL       551    551       Magnesium or manganese.
FT                                {ECO:0000256|PIRSR:PIRSR009407-3}.
FT   METAL       555    555       Magnesium or manganese.
FT                                {ECO:0000256|PIRSR:PIRSR009407-3}.
FT   BINDING     147    147       Substrate. {ECO:0000256|PIRSR:
FT                                PIRSR009407-2}.
FT   BINDING     550    550       Substrate. {ECO:0000256|PIRSR:
FT                                PIRSR009407-2}.
FT   SITE        257    257       Critical for catalysis.
FT                                {ECO:0000256|PIRSR:PIRSR009407-1}.
FT   SITE        422    422       Critical for catalysis.
FT                                {ECO:0000256|PIRSR:PIRSR009407-1}.
SQ   SEQUENCE   745 AA;  82641 MW;  7000A5AF2B129014 CRC64;
     MAGEKSTIIY TLTDEAPLLA TYSLLPIIET FTKPAGIEIV KSDISVAARV LAEFADYLSE
     EQKVSDNLAE LGRLTQDPDT NIIKLPNISA SVAQLTACIK ELQSKGYAIP DYPENPATEE
     EKTIKARYGK CLGSAVNPVL REGNSDRRAP AAVKNYAKKH PHSMSEWKQW SQTHVSHMEE
     GDFYHGEKSM TLDRPRNVKM ELITNSGKSI VLKPKVALQE GEIIDSMFMS KKALCDFYEK
     QLDDCREAGI LFSLHVKATM MKVSHPIVFG HCVKIYYKEA FEKHGKLFDE LGINVNNGMA
     GLYEKIETLP TSLREEIIED LHACQEHRPA LAMVDSAKGI TNFHSPNDII VDASMPAMIR
     AGGKMWGADG KQYDAKAVMP ESTFARIYQE MINFCKWHGN FDPKTMGTVP NVGLMAQKAE
     EYGSHDKTFE IPEAGIANIT DLDTGEVLLT QNVEEGDIWR MCQVKDAPIR DWVKLAVTRA
     RNSGMPAIFW LDPYRPHENE LIKKVQKYLK DHDTTGLDIQ IMSQVRAMRY TLERVVRGLD
     TISVTGNILR DYLTDLFPIM ELGTSAKMLS IVPLMAGGGM YETGAGGSAP KHVQQLVEEN
     HLRWDSLGEF LALAVSLEEM GIKENNARAK LLAKTLDEAT GKLLDNDKSP SRRTGELDNR
     GSHFYLSLYW AEALAAQDED AELKAKFAPL AKALAENEQK IVAELAQVQG KPADIGGYYA
     VDPAKVSAVM RPSATFNAAL STVQA
//
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