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Database: UniProt/TrEMBL
Entry: A0A0K9KGQ1_HAEIF
LinkDB: A0A0K9KGQ1_HAEIF
Original site: A0A0K9KGQ1_HAEIF 
ID   A0A0K9KGQ1_HAEIF        Unreviewed;       394 AA.
AC   A0A0K9KGQ1;
DT   11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT   11-NOV-2015, sequence version 1.
DT   27-SEP-2017, entry version 15.
DE   RecName: Full=Elongation factor Tu {ECO:0000256|HAMAP-Rule:MF_00118, ECO:0000256|RuleBase:RU004061};
DE            Short=EF-Tu {ECO:0000256|HAMAP-Rule:MF_00118};
GN   Name=tuf {ECO:0000256|HAMAP-Rule:MF_00118,
GN   ECO:0000313|EMBL:KMZ25380.1};
GN   Synonyms=tuf_1 {ECO:0000313|EMBL:CWX14844.1}, tufA_1
GN   {ECO:0000313|EMBL:KIS36709.1};
GN   ORFNames=ABN48_09130 {ECO:0000313|EMBL:KMZ25380.1}, ERS515255_01677
GN   {ECO:0000313|EMBL:CWX14844.1}, ERS515279_01572
GN   {ECO:0000313|EMBL:CWX38268.1}, NTHI1209_00127
GN   {ECO:0000313|EMBL:KIS36709.1};
OS   Haemophilus influenzae.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC   Pasteurellaceae; Haemophilus.
OX   NCBI_TaxID=727 {ECO:0000313|EMBL:KMZ25380.1, ECO:0000313|Proteomes:UP000037430};
RN   [1] {ECO:0000313|EMBL:KIS36709.1, ECO:0000313|Proteomes:UP000050700}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=1209 {ECO:0000313|EMBL:KIS36709.1,
RC   ECO:0000313|Proteomes:UP000050700};
RA   Atack J.M., Fox K.L., Power P.M., Clark T., Jurcisek J., Korlach J.,
RA   Bakaletz L.O., Jennings M.P.;
RT   "Methylome analysis of the phasevarions of Haemophilus influenzae.";
RL   Submitted (MAY-2014) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:KMZ25380.1, ECO:0000313|Proteomes:UP000037430}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=HI1408 {ECO:0000313|EMBL:KMZ25380.1,
RC   ECO:0000313|Proteomes:UP000037430};
RA   VanWagoner T.M., Mussa H., Whitby P.W., Morton D.J., Seale T.W.,
RA   Stull T.L.;
RT   "Genome sequences of invasive non-typeable Haemophilus influenzae.";
RL   Submitted (JUN-2015) to the EMBL/GenBank/DDBJ databases.
RN   [3] {ECO:0000313|EMBL:CWX14844.1, ECO:0000313|Proteomes:UP000070891, ECO:0000313|Proteomes:UP000072960}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=2842STDY5882051 {ECO:0000313|EMBL:CWX14844.1,
RC   ECO:0000313|Proteomes:UP000072960}, and 2842STDY5882075
RC   {ECO:0000313|EMBL:CWX38268.1, ECO:0000313|Proteomes:UP000070891};
RG   Pathogen Informatics;
RL   Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: This protein promotes the GTP-dependent binding of
CC       aminoacyl-tRNA to the A-site of ribosomes during protein
CC       biosynthesis. {ECO:0000256|HAMAP-Rule:MF_00118}.
CC   -!- SUBUNIT: Monomer. {ECO:0000256|HAMAP-Rule:MF_00118}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00118}.
CC   -!- SIMILARITY: Belongs to the TRAFAC class translation factor GTPase
CC       superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A
CC       subfamily. {ECO:0000256|HAMAP-Rule:MF_00118}.
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DR   EMBL; FFIH01000012; CWX14844.1; -; Genomic_DNA.
DR   EMBL; FFIN01000005; CWX38268.1; -; Genomic_DNA.
DR   EMBL; JMQP01000001; KIS36709.1; -; Genomic_DNA.
DR   EMBL; LFDJ01000020; KMZ25380.1; -; Genomic_DNA.
DR   RefSeq; WP_005654658.1; NZ_MPJI01000012.1.
DR   EnsemblBacteria; CWX14844; CWX14844; ERS515255_01677.
DR   EnsemblBacteria; CWX38268; CWX38268; ERS515279_01572.
DR   EnsemblBacteria; KIS36709; KIS36709; NTHI1209_00127.
DR   EnsemblBacteria; KMZ25380; KMZ25380; ABN48_09130.
DR   KEGG; hic:NTHIC486_00369; -.
DR   KEGG; hiw:NTHI477_01689; -.
DR   KEGG; hiw:NTHI477_01728; -.
DR   KEGG; hix:NTHI723_01115; -.
DR   PATRIC; fig|727.529.peg.1669; -.
DR   KO; K02358; -.
DR   Proteomes; UP000037430; Unassembled WGS sequence.
DR   Proteomes; UP000050700; Unassembled WGS sequence.
DR   Proteomes; UP000070891; Unassembled WGS sequence.
DR   Proteomes; UP000072960; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR   GO; GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-UniRule.
DR   CDD; cd03697; EFTU_II; 1.
DR   HAMAP; MF_00118_B; EF_Tu_B; 1.
DR   InterPro; IPR004161; EFTu-like_2.
DR   InterPro; IPR033720; EFTU_2.
DR   InterPro; IPR031157; G_TR_CS.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR005225; Small_GTP-bd_dom.
DR   InterPro; IPR000795; TF_GTP-bd_dom.
DR   InterPro; IPR009000; Transl_B-barrel.
DR   InterPro; IPR009001; Transl_elong_EF1A/Init_IF2_C.
DR   InterPro; IPR004541; Transl_elong_EFTu/EF1A_bac/org.
DR   InterPro; IPR004160; Transl_elong_EFTu/EF1A_C.
DR   Pfam; PF00009; GTP_EFTU; 1.
DR   Pfam; PF03144; GTP_EFTU_D2; 1.
DR   Pfam; PF03143; GTP_EFTU_D3; 1.
DR   PRINTS; PR00315; ELONGATNFCT.
DR   SUPFAM; SSF50447; SSF50447; 1.
DR   SUPFAM; SSF50465; SSF50465; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00485; EF-Tu; 1.
DR   TIGRFAMs; TIGR00231; small_GTP; 1.
DR   PROSITE; PS00301; G_TR_1; 1.
DR   PROSITE; PS51722; G_TR_2; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000037430,
KW   ECO:0000313|Proteomes:UP000050700, ECO:0000313|Proteomes:UP000070891,
KW   ECO:0000313|Proteomes:UP000072960};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00118};
KW   Elongation factor {ECO:0000256|HAMAP-Rule:MF_00118,
KW   ECO:0000313|EMBL:KMZ25380.1};
KW   GTP-binding {ECO:0000256|HAMAP-Rule:MF_00118};
KW   Hydrolase {ECO:0000313|EMBL:KMZ25380.1};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00118};
KW   Protein biosynthesis {ECO:0000256|HAMAP-Rule:MF_00118}.
FT   DOMAIN       10    204       Tr-type G. {ECO:0000259|PROSITE:PS51722}.
FT   NP_BIND      19     26       GTP. {ECO:0000256|HAMAP-Rule:MF_00118}.
FT   NP_BIND      81     85       GTP. {ECO:0000256|HAMAP-Rule:MF_00118}.
FT   NP_BIND     136    139       GTP. {ECO:0000256|HAMAP-Rule:MF_00118}.
SQ   SEQUENCE   394 AA;  43297 MW;  2D3ABC985BAA732D CRC64;
     MSKEKFERTK PHVNVGTIGH VDHGKTTLTA AITTVLAKHY GGAARAFDQI DNAPEEKARG
     ITINTSHVEY DTPTRHYAHV DCPGHADYVK NMITGAAQMD GAILVVAATD GPMPQTREHI
     LLGRQVGVPY IIVFLNKCDM VDDEELLELV EMEVRELLSQ YDFPGDDTPI VRGSALQALN
     GVAEWEEKIL ELAGHLDTYI PEPERAIDQP FLLPIEDVFS ISGRGTVVTG RVERGIIRTG
     DEVEIVGIKD TAKTTVTGVE MFRKLLDEGR AGENIGALLR GTKREEIERG QVLAKPGSIT
     PHTDFESEVY VLSKDEGGRH TPFFKGYRPQ FYFRTTDVTG TIELPEGVEM VMPGDNIKMT
     VSLIHPIAMD QGLRFAIREG GRTVGAGVVA KIIK
//
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