ID A0A0L8H2F2_OCTBM Unreviewed; 2082 AA.
AC A0A0L8H2F2;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 24-JAN-2024, entry version 35.
DE RecName: Full=SET domain-containing protein {ECO:0000259|PROSITE:PS50280};
GN ORFNames=OCBIM_22024077mg {ECO:0000313|EMBL:KOF83274.1};
OS Octopus bimaculoides (California two-spotted octopus).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Cephalopoda;
OC Coleoidea; Octopodiformes; Octopoda; Incirrata; Octopodidae; Octopus.
OX NCBI_TaxID=37653 {ECO:0000313|EMBL:KOF83274.1};
RN [1] {ECO:0000313|EMBL:KOF83274.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=UCB-OBI-ISO-001 {ECO:0000313|EMBL:KOF83274.1};
RC TISSUE=Gonad {ECO:0000313|EMBL:KOF83274.1};
RA Tran T., Druce J.;
RT "MeaNS - Measles Nucleotide Surveillance Program.";
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KQ419533; KOF83274.1; -; Genomic_DNA.
DR RefSeq; XP_014776058.1; XM_014920572.1.
DR STRING; 37653.A0A0L8H2F2; -.
DR EnsemblMetazoa; Ocbimv22024077m; Ocbimv22024077m.p; Ocbimv22024077m.g.
DR EnsemblMetazoa; XM_014920572.1; XP_014776058.1; LOC106873279.
DR GeneID; 106873279; -.
DR KEGG; obi:106873279; -.
DR OMA; KHLMNEW; -.
DR OrthoDB; 2919208at2759; -.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd15550; PHD_MLL5; 1.
DR CDD; cd10529; SET_SETD5-like; 1.
DR Gene3D; 2.170.270.10; SET domain; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR001214; SET_dom.
DR InterPro; IPR046341; SET_dom_sf.
DR InterPro; IPR019786; Zinc_finger_PHD-type_CS.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR001965; Znf_PHD.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR46462; UPSET, ISOFORM A; 1.
DR PANTHER; PTHR46462:SF3; UPSET, ISOFORM A; 1.
DR Pfam; PF20826; PHD_5; 1.
DR Pfam; PF00856; SET; 1.
DR SMART; SM00249; PHD; 1.
DR SMART; SM00317; SET; 1.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR SUPFAM; SSF82199; SET domain; 1.
DR PROSITE; PS50280; SET; 1.
DR PROSITE; PS01359; ZF_PHD_1; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 352..471
FT /note="SET"
FT /evidence="ECO:0000259|PROSITE:PS50280"
FT REGION 64..92
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 195..214
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 222..298
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 740..766
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 792..875
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 912..949
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1032..1051
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1085..1136
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1168..1195
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1234..1263
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1547..1572
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1588..2082
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 66..86
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 195..211
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 228..246
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 247..275
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 279..298
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 792..821
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 829..843
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 844..875
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 933..949
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1090..1123
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1171..1192
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1556..1570
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1592..1643
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1648..1664
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1690..1705
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1707..1744
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1745..1764
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1767..1853
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1856..1887
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1888..1943
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1944..1960
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1961..2049
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2050..2082
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2082 AA; 225953 MW; 69FCE6D116F17A6A CRC64;
MSLVARQELI APASAAVKMA AGTHPESREA VCAAATTQED PNYPPPEAYA RCFGLPYQVK
LDHNYVAPPP PTPPQSPPPL PTQPPPSSKI NGHLEIDVSS VPAVKEKDVD TEDSITRCIC
ELQHDDGYMI CCDKCSVWQH IDCMGVRNNI PDSYFCEKCE PRQVDVEKAR LIQTRKLEEL
TGSYSDIRYE AVKGKNRVTG EHTDTSATDT DPEEVNNRMM ALVEKNKKTK RTKQKPVKKK
RMKAAKENKK ENKDKEPTVN KKQKMPKDTA KKTPRTKAAR KVQISSTVDN GDTRGPWNIS
AKSMVQEHEK EHEKGTEKLH GNILSIAVLE ALSKVKVNGQ MSPEKHIKRE ELLVQLCELA
CLQKNKKGLQ ATENLKEGQL ISEYVGRVSL KEECINASMK RLKPFTLVYS KLEGAELFID
ASTLGNVSRY IRRSCSPNAE MRHLLHHGFI RFLIYSTKVI SKGAEITIPF DFTREDGVLH
TECACSRINC PLSKPKTKKI NINRNRRKIK NKSIPENMLD SVSDSACIGV MPSIISSTIN
NDPTDADTKA AAVAAAMAVA AAAEAQPLAI PLEMKPPRSS NANVIYKTIP SSPSIPTSMV
KLYPSSQTSQ PASRSSVYTH ANTTGTSLSP TISLPVSIVS SELSIQASPN NCSVSSISLP
PIPSAPMPLT MPAKSACTLE DLAAVATAPN AAMAAIAVSN NSNSDAPMLQ LPPPPTPTEA
EAAAAAAAAV DAAVAAPPLP THVEGEISPT IDDNLEPPRK MTREERKMEA IVKAFEKLEK
REERRKEALA RLENARKSQE EKKRESPEDE EKVELKDTKP DISTLSKPPS TKKKKKAHPI
STRRRSRVNS GGSCSEAALS QDENSNMGSN QTTALSSPLA VAPSLVVTLA GQISSPQPVT
VTAPTTVTTI TPTTSLSSSL SQTPPVQPPP QSAPQNINQQ NDISNTPSSF KFKTKKMSEW
LEGKDTKTVL PATKTEPLEV NIEETAFVTC FHSPRSSLEH LHRRMSHISV SGKMDSSVGS
AKKRWLRQAM HETGPTGMDS GKDSPQPINS VVCDVASPNA VASMPSPGAS PQADFVTPLK
KRRLARESLS SDQPLMSTPS TSSPSQTSNL DVPSTSAHSI SFEDSDIKSS HQLKSPPEDL
HLEKYKLISA EANYSGMGSE LRDLIESDTC ESQPPPYSDS TRGISDSEET SGPEGLESLA
AAAEQCSAVD VSSCNSRTNL LSQVTTLQSM TADHVKSECE DDETLDASET TEHQNPDTLD
SANHFEQNSI KEEIACETKE LTNTKPLSEN STWTTLFHDS LKDHVEGEIK HSEAMASNSL
AVQPVFTNFS NVFKKQKENS SDIHPFEIKK EKIQETCDDK ISSINEVKSS EYSQKHVLEN
SVDHAETPTC DSGTNIHFSL EKEVPKSECS VLPVRRDSCQ FSPQAGKDGR NQASDVVSVG
ESIDSKIRET HHQNTSCATH LQSDLCTSVR ISVTEKENSI RNEVEMDTST NVANYGQLPA
PVEIDTLINT VLPTVPAPNL ILESSLPTKA PSKKKVSLLE YRKRLKEKKD PNAASAYSQG
KVSTKSTPVP ADKAPTLAVL PLFVEPVSPA KENESSEVKE HRDKKSESRW TEKPMSLTER
LRQEFGLEES DEEENKTESK WHCKRQSVQT PPPPPPPPSS VQPHLHHPGN PSGEELLAEP
LPVAPSHSVL TQYPPLQNQL QGSMLSGRPP LPPPPPPPHQ SRLLIPNQST PLPPPPPPPS
TVAVSESPVI PSLMSIQTYH QRFQAPAGQP GPPPPLPTQN QLPPPPPQQV PPPGPVVSAA
PPPPPPMPLI TSPRPPCVVG PPPPPPNVQA GPQQPPPPQQ QPQQQPPPPL PQISQHHTHY
AYQGVVSSAS HLQSSTQTTQ FSHPAPVPAV SSQPPQYPPG PPPPVSQATA NYGPPPPQLP
GPALQQSQFT HPPPPPPPPN TGQIPCQGQS LVLQNQSTAN FQMPPPPPPP PHGTTYVRQP
PPPPQAILPP PPNGGSYPPP PQHVAPPYVP PPAPTGNPSN HPPPQPFTTT QTQQPLPPPP
PPPPPQQQQQ QQQPYTINQT QLSSSTPKTY FPRSKYNQSQ NY
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