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Database: UniProt/TrEMBL
Entry: A0A0M1T200_KLEPN
LinkDB: A0A0M1T200_KLEPN
Original site: A0A0M1T200_KLEPN 
ID   A0A0M1T200_KLEPN        Unreviewed;       394 AA.
AC   A0A0M1T200;
DT   11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT   11-NOV-2015, sequence version 1.
DT   25-OCT-2017, entry version 19.
DE   RecName: Full=Elongation factor Tu {ECO:0000256|HAMAP-Rule:MF_00118, ECO:0000256|RuleBase:RU004061};
DE            Short=EF-Tu {ECO:0000256|HAMAP-Rule:MF_00118};
GN   Name=tuf {ECO:0000256|HAMAP-Rule:MF_00118,
GN   ECO:0000313|EMBL:AST72277.1};
GN   ORFNames=B5K12_04375 {ECO:0000313|EMBL:OWU97730.1}, B5K12_17440
GN   {ECO:0000313|EMBL:OWU95260.1}, CI103_02020
GN   {ECO:0000313|EMBL:AST72277.1}, CI103_26245
GN   {ECO:0000313|EMBL:AST76730.1}, RJA_26045
GN   {ECO:0000313|EMBL:ARV42415.1};
OS   Klebsiella pneumoniae subsp. pneumoniae.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Klebsiella.
OX   NCBI_TaxID=72407 {ECO:0000313|EMBL:ARV42415.1};
RN   [1] {ECO:0000313|EMBL:ARV42415.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=RJA166 {ECO:0000313|EMBL:ARV42415.1};
RA   Qu H., Ou H.-Y.;
RT   "The complete genome sequence of K1 hypervirulent Klebsiella
RT   pneumoniae RJA166.";
RL   Submitted (JAN-2017) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:OWU95260.1, ECO:0000313|Proteomes:UP000197539}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=KpvST23L_OXA-48 {ECO:0000313|EMBL:OWU95260.1,
RC   ECO:0000313|Proteomes:UP000197539};
RA   Turton J.F., Payne Z., Turton J.A., Hopkins K.L., Coward A.,
RA   Doumith M.;
RT   "Virulence genes in isolates of Klebsiella pneumoniae from the United
RT   Kingdom during 2016, including among carbapenemase positive
RT   hypervirulent K1-ST23 and non-hypervirulent types ST147, ST15 and
RT   ST383.";
RL   Submitted (MAR-2017) to the EMBL/GenBank/DDBJ databases.
RN   [3] {ECO:0000313|EMBL:AST72277.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=AUSMDU00008079 {ECO:0000313|EMBL:AST72277.1};
RA   Kwong J.C., Lane C., Romanes F., Goncalves da Silva A., Easton M.,
RA   Cronin K., Waters M.J., Tomita T., Stevens K., Schultz M.B.,
RA   Baines S.L., Sherry N.L., Carter G., Mu A., Sait M., Ballard S.A.,
RA   Seemann T., Stinear T.P., Howden B.P.;
RT   "Real-time genomic and epidemiological investigation of a multi-
RT   institutional outbreak of KPC-producing Enterobacteriaceae reveals
RT   complex transmission dynamics and informs management responses.";
RL   Submitted (AUG-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: This protein promotes the GTP-dependent binding of
CC       aminoacyl-tRNA to the A-site of ribosomes during protein
CC       biosynthesis. {ECO:0000256|HAMAP-Rule:MF_00118}.
CC   -!- SUBUNIT: Monomer. {ECO:0000256|HAMAP-Rule:MF_00118}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00118}.
CC   -!- SIMILARITY: Belongs to the TRAFAC class translation factor GTPase
CC       superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A
CC       subfamily. {ECO:0000256|HAMAP-Rule:MF_00118}.
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DR   EMBL; CP019047; ARV42415.1; -; Genomic_DNA.
DR   EMBL; CP022691; AST72277.1; -; Genomic_DNA.
DR   EMBL; CP022691; AST76730.1; -; Genomic_DNA.
DR   EMBL; MZMX01000025; OWU95260.1; -; Genomic_DNA.
DR   EMBL; MZMX01000006; OWU97730.1; -; Genomic_DNA.
DR   RefSeq; WP_004174069.1; NZ_MZMX01000025.1.
DR   SMR; A0A0M1T200; -.
DR   EnsemblBacteria; AIW74358; AIW74358; KPNIH32_01100.
DR   EnsemblBacteria; AIW78919; AIW78919; KPNIH32_25445.
DR   KEGG; kpg:KPNIH32_01100; -.
DR   KEGG; kpg:KPNIH32_25445; -.
DR   KEGG; kpt:VK055_3117; -.
DR   KEGG; kpt:VK055_3750; -.
DR   KEGG; kpv:KPNIH29_01060; -.
DR   KEGG; kpv:KPNIH29_24130; -.
DR   KEGG; kpw:KPNIH30_01095; -.
DR   KEGG; kpw:KPNIH30_24575; -.
DR   KEGG; kpy:KPNIH31_01090; -.
DR   KEGG; kpy:KPNIH31_23630; -.
DR   KO; K02358; -.
DR   Proteomes; UP000197539; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR   GO; GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-UniRule.
DR   CDD; cd03697; EFTU_II; 1.
DR   HAMAP; MF_00118_B; EF_Tu_B; 1.
DR   InterPro; IPR004161; EFTu-like_2.
DR   InterPro; IPR033720; EFTU_2.
DR   InterPro; IPR031157; G_TR_CS.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR005225; Small_GTP-bd_dom.
DR   InterPro; IPR000795; TF_GTP-bd_dom.
DR   InterPro; IPR009000; Transl_B-barrel.
DR   InterPro; IPR009001; Transl_elong_EF1A/Init_IF2_C.
DR   InterPro; IPR004541; Transl_elong_EFTu/EF1A_bac/org.
DR   InterPro; IPR004160; Transl_elong_EFTu/EF1A_C.
DR   Pfam; PF00009; GTP_EFTU; 1.
DR   Pfam; PF03144; GTP_EFTU_D2; 1.
DR   Pfam; PF03143; GTP_EFTU_D3; 1.
DR   PRINTS; PR00315; ELONGATNFCT.
DR   SUPFAM; SSF50447; SSF50447; 1.
DR   SUPFAM; SSF50465; SSF50465; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00485; EF-Tu; 1.
DR   TIGRFAMs; TIGR00231; small_GTP; 1.
DR   PROSITE; PS00301; G_TR_1; 1.
DR   PROSITE; PS51722; G_TR_2; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000197539};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00118};
KW   Elongation factor {ECO:0000256|HAMAP-Rule:MF_00118,
KW   ECO:0000313|EMBL:ARV42415.1};
KW   GTP-binding {ECO:0000256|HAMAP-Rule:MF_00118};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00118};
KW   Protein biosynthesis {ECO:0000256|HAMAP-Rule:MF_00118}.
FT   DOMAIN       10    204       Tr-type G. {ECO:0000259|PROSITE:PS51722}.
FT   NP_BIND      19     26       GTP. {ECO:0000256|HAMAP-Rule:MF_00118}.
FT   NP_BIND      81     85       GTP. {ECO:0000256|HAMAP-Rule:MF_00118}.
FT   NP_BIND     136    139       GTP. {ECO:0000256|HAMAP-Rule:MF_00118}.
SQ   SEQUENCE   394 AA;  43246 MW;  DBA4133541205DD8 CRC64;
     MSKEKFERTK PHVNVGTIGH VDHGKTTLTA AITTVLAKTY GGSARAFDQI DNAPEEKARG
     ITINTSHVEY DTPTRHYAHV DCPGHADYVK NMITGAAQMD GAILVVAATD GPMPQTREHI
     LLGRQVGVPY IIVFLNKCDM VDDEELLELV EMEVRELLSQ YDFPGDDTPI VRGSALKALE
     GDAEWEAKII ELAGHLDTYI PEPERAIDKP FLLPIEDVFS ISGRGTVVTG RVERGIIKVG
     EEVEIVGIKE TAKTTCTGVE MFRKLLDEGR AGENVGVLLR GIKREEIERG QVLAKPGTIN
     PHTKFESEVY ILSKDEGGRH TPFFKGYRPQ FYFRTTDVTG TIELPEGVEM VMPGDNIKMV
     VTLIHPIAMD DGLRFAIREG GRTVGAGVVA KVLG
//
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