ID A0A119KM73_9BURK Unreviewed; 342 AA.
AC A0A119KM73;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=alcohol dehydrogenase {ECO:0000256|ARBA:ARBA00013190};
DE EC=1.1.1.1 {ECO:0000256|ARBA:ARBA00013190};
GN ORFNames=WT44_03255 {ECO:0000313|EMBL:KWA67460.1}, WT74_26510
GN {ECO:0000313|EMBL:AOK56276.1};
OS Burkholderia stagnalis.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Burkholderia; Burkholderia cepacia complex.
OX NCBI_TaxID=1503054 {ECO:0000313|EMBL:KWA67460.1};
RN [1] {ECO:0000313|EMBL:KWA67460.1, ECO:0000313|Proteomes:UP000068603}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MSMB1960WGS {ECO:0000313|EMBL:KWA67460.1,
RC ECO:0000313|Proteomes:UP000068603};
RA Sahl J., Keim P., Wagner D.;
RT "Expanding the genomic diversity of Burkholderia species for the
RT development of highly accurate diagnostics.";
RL Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:AOK56276.1, ECO:0000313|Proteomes:UP000094682}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MSMB735WGS {ECO:0000313|EMBL:AOK56276.1,
RC ECO:0000313|Proteomes:UP000094682};
RA Sahl J., Wagner D., Keim P.;
RT "Diversity of Burkholderia near neighbor genomes.";
RL Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947,
CC ECO:0000256|RuleBase:RU361277};
CC -!- SIMILARITY: Belongs to the zinc-containing alcohol dehydrogenase
CC family. {ECO:0000256|ARBA:ARBA00008072, ECO:0000256|RuleBase:RU361277}.
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DR EMBL; CP013461; AOK56276.1; -; Genomic_DNA.
DR EMBL; LPHB01000012; KWA67460.1; -; Genomic_DNA.
DR RefSeq; WP_060018207.1; NZ_LPMY01000080.1.
DR AlphaFoldDB; A0A119KM73; -.
DR STRING; 1503054.WT74_26510; -.
DR GeneID; 46329657; -.
DR KEGG; bstg:WT74_26510; -.
DR Proteomes; UP000068603; Unassembled WGS sequence.
DR Proteomes; UP000094682; Chromosome 2.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd08297; CAD3; 1.
DR Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR013149; ADH-like_C.
DR InterPro; IPR013154; ADH-like_N.
DR InterPro; IPR002328; ADH_Zn_CS.
DR InterPro; IPR011032; GroES-like_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR020843; PKS_ER.
DR PANTHER; PTHR42940; ALCOHOL DEHYDROGENASE 1-RELATED; 1.
DR PANTHER; PTHR42940:SF8; VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 11; 1.
DR Pfam; PF08240; ADH_N; 1.
DR Pfam; PF00107; ADH_zinc_N; 1.
DR SMART; SM00829; PKS_ER; 1.
DR SUPFAM; SSF50129; GroES-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS00059; ADH_ZINC; 1.
PE 3: Inferred from homology;
KW Metal-binding {ECO:0000256|RuleBase:RU361277};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Zinc {ECO:0000256|RuleBase:RU361277}.
FT DOMAIN 14..338
FT /note="Enoyl reductase (ER)"
FT /evidence="ECO:0000259|SMART:SM00829"
SQ SEQUENCE 342 AA; 36028 MW; 8A5B4238059CEE28 CRC64;
MTQTMKAAVV HAFGEPLRIE EVPVPTPGPG QILVNIKASG VCHTDLHAAD GDWPVKPSLP
FIPGHEGVGV VAAVGAGVTH VREGDRVGVP WLYTACGHCE HCYSGWETLC HQQQNTGYSV
NGSYAEYVLA DPDYVGHLPA QVAFDEIAPI LCAGVTVYKG IRVTDTRPGQ WLAISGIGGL
GHVAVQYARA MGLHVAAIDV AQDKLALAKQ LGAELTIDAS TSDPAAIIQK EIGGAHGVLV
TAVSRSAFAQ ALGMVRRGGT VALNGLPPGD FPLPIFSTVL NGITVRGSIV GTRRDLQESL
DFAADGLVRA HIHRDRLGNI NEIFAKLRAG QVDGRVVLTE MR
//
