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Database: UniProt/TrEMBL
Entry: A0A127D7L4_9BACI
LinkDB: A0A127D7L4_9BACI
Original site: A0A127D7L4_9BACI 
ID   A0A127D7L4_9BACI        Unreviewed;      4956 AA.
AC   A0A127D7L4;
DT   08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT   08-JUN-2016, sequence version 1.
DT   25-OCT-2017, entry version 12.
DE   SubName: Full=Thioester reductase {ECO:0000313|EMBL:AMM92984.1};
GN   ORFNames=UP17_11020 {ECO:0000313|EMBL:AMM92984.1};
OS   Bacillus simplex.
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=1478 {ECO:0000313|EMBL:AMM92984.1, ECO:0000313|Proteomes:UP000070470};
RN   [1] {ECO:0000313|EMBL:AMM92984.1, ECO:0000313|Proteomes:UP000070470}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SH-B26 {ECO:0000313|EMBL:AMM92984.1,
RC   ECO:0000313|Proteomes:UP000070470};
RA   van der Voort M., Raaijmakers J.;
RT   "Beneficial Bacilli from the sugar beet rhizosphere.";
RL   Submitted (MAR-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation
CC       of feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00258}.
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DR   EMBL; CP011008; AMM92984.1; -; Genomic_DNA.
DR   RefSeq; WP_061463047.1; NZ_CP011008.1.
DR   EnsemblBacteria; AMM92984; AMM92984; UP17_11020.
DR   GeneID; 29409059; -.
DR   KEGG; bsj:UP17_11020; -.
DR   PATRIC; fig|1478.10.peg.2516; -.
DR   Proteomes; UP000070470; Chromosome.
DR   GO; GO:0016788; F:hydrolase activity, acting on ester bonds; IEA:InterPro.
DR   GO; GO:0031177; F:phosphopantetheine binding; IEA:InterPro.
DR   GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR   Gene3D; 1.10.1200.10; -; 4.
DR   Gene3D; 3.40.50.1820; -; 1.
DR   InterPro; IPR010071; AA_adenyl_domain.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR036736; ACP-like_sf.
DR   InterPro; IPR025110; AMP-bd_C.
DR   InterPro; IPR020845; AMP-binding_CS.
DR   InterPro; IPR000873; AMP-dep_Synth/Lig.
DR   InterPro; IPR001242; Condensatn.
DR   InterPro; IPR010060; NRPS_synth.
DR   InterPro; IPR020806; PKS_PP-bd.
DR   InterPro; IPR009081; PP-bd_ACP.
DR   InterPro; IPR006162; Ppantetheine_attach_site.
DR   InterPro; IPR001031; Thioesterase.
DR   Pfam; PF00501; AMP-binding; 4.
DR   Pfam; PF13193; AMP-binding_C; 4.
DR   Pfam; PF00668; Condensation; 5.
DR   Pfam; PF00550; PP-binding; 4.
DR   Pfam; PF00975; Thioesterase; 1.
DR   SMART; SM00823; PKS_PP; 4.
DR   SUPFAM; SSF47336; SSF47336; 4.
DR   SUPFAM; SSF53474; SSF53474; 1.
DR   TIGRFAMs; TIGR01733; AA-adenyl-dom; 4.
DR   TIGRFAMs; TIGR01720; NRPS-para261; 1.
DR   PROSITE; PS50075; ACP_DOMAIN; 4.
DR   PROSITE; PS00455; AMP_BINDING; 4.
DR   PROSITE; PS00012; PHOSPHOPANTETHEINE; 4.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000070470}.
FT   DOMAIN     1004   1071       Carrier. {ECO:0000259|PROSITE:PS50075}.
FT   DOMAIN     2047   2114       Carrier. {ECO:0000259|PROSITE:PS50075}.
FT   DOMAIN     3103   3169       Carrier. {ECO:0000259|PROSITE:PS50075}.
FT   DOMAIN     4621   4688       Carrier. {ECO:0000259|PROSITE:PS50075}.
SQ   SEQUENCE   4956 AA;  563789 MW;  BA592A1623B63938 CRC64;
     MRSDLLAKLD SLSPEKREWL QKQMQKKEKE TLPLSYAQQR LWFMDRFNPN SSLYNIPTVW
     RLKGHWLPGA LEKGLNRLIE RHDSLRTVFK EVGDQPVQHI VEYLPGKLPV EDYSHLPLEV
     KEKEIESLIA REAQEPFDLM NGPLIRNQLV QLGKDEWLLL CTMHHIISDA WSIGILINEL
     LAFYEEETSG KPAGLNSLSI QYADFAKWQK QWLQGEVLDR QLTYWQEELS GELPILQLPL
     DCPRPVTQTY AGDTCRVIVP HTLLSALKNL SQREGSTLFM TLMAAYQSFL ARYTGQNDIL
     VGSPIANRNH KGVEELIGFF VNTLVYRADL NGAPTFQEIL SQIKKKALKA YEYQDIPFEK
     VVEAVQPERS TSHSPIFQTM FTLQNIKQER LELSGRSLEM IESNISIAKF DLSLTAYEVE
     EDLHVTFEYN TDLFDSRTIA RMAGHFENWL NEIVHHPDES YTNLTMLSDT EQKQLLEEWN
     DTDAVYAHES MIHELFEQQV ARTPEAVAVV YEGGQLTYQE LNEKANKMAH YLQKRDIGPE
     SLVGICFERS PDMMIGLLGI LKAGGAYVPL DPSYPENRLR YILKDSQIQV LLTKEALQGW
     LPEGIQAICL DRDQAAISKE SGLAPVSGVT AKNLAYIIYT SGSTGNPKGV MIEHHSVINR
     LQWMQKNYPL SEQDTILQKT PFSFDVSVWE LFWWSFVGAR VCLLPPGGEK DPAMIEECIE
     RYRVTTMHFV PSMLSAFLDY MEKSKAKKDV SSLCQVFTSG EALNSEQVRR FKGVFYDFQQ
     TKLSNLYGPT EATVDVTYYN CDLEKELMLI PIGRPIDNTD LYVLDQNQQV VPVGVAGELY
     LGGVGLARGY FNRPELTAER FIPHPFKEGE RLYRTGDLVR YLNDRNLEYI GRVDNQVKIR
     GFRIELGEVE AVLHDHPSVK EAVVLVREDH PGDKRLVAYV VGEGNTGEWR EHLKAQLPNY
     MVPAYFVEME AMPLTPNSKI DRKALLALEG QSVSADIVLP RTPGEELIAS VWSQVLGIGN
     IGVQASFFEL GGHSLLATQV VSRLQEVFQI ELPLRELFEY STVEALAKRL DQLRKGDKKR
     EIPPLMPMER GDAIPLSYAQ QRLWFIDQFT PNSALYNMPM VCRLTGNWVP EALEKGWNQL
     IERHESLRTV FHEVDGHPVQ QIQPHAFRSL SQMDLTMLSP EERESEVKRL LQQETEVPFD
     LEEGPLIRTI LLRVGEEEWV LLCTLHHIVS DGWSMGVLLE EWIAFYKEAM GEKEAELEPL
     PIQYADFAQW QKGWLKEEVL EQQLHYWQEE LSGELPLLQL PMDRPRPAVQ THRGSTHTVL
     LSRSLRDKLN EISRQEGSTL FMTLLAAYQS FLSRYTGQED ILVGSPIANR NYRESEGLIG
     FFVNTLVYRA DLSGTPTFQD ILSRVRQKAL NAYEYQDIPF EKVVEVVQPE RSTSHSPIFQ
     TMFILQNMKQ ELPVLADRRI EMIESHSPIA KFDLSVMAAE TEEGLLFAFE YNKDLFDVTT
     IERMAGHFET WLNEVSHHPQ KPLNSLGMLS EFERDLLVET WNDTAMEMSQ VGLICDGFED
     QVARRPGAIA VVDQMREWTY GELDARANQL AHVLQRKGVV PESVVGVYLP RSAELMASLL
     GILKAGGAYV VLDPLYPKSR LQYMIEDAGV QIVVTTAAQE SLSEQVETVR LEEITDESVI
     APKRRVKPEH LAYIVYTSGS TGKPKGVMVE YRSLMNMVSW HQAVYQITAQ DRATQIAGIA
     FDSAVQEIWP YLTAGAALYL STEELRINPE ALRDWLIDSR ITASFAPTPI LERLLKLSWP
     EKTDLRFIIT GGDQLTQYPS EQIPFAVINQ YGPSENTVVA TDCYVPVGMS TGTPSIGRPI
     ANTEVYVLDS HLQPVPVGVI GDLYIGGKSL ARGYANRPEL TEEKFILHPF KSGERLYFTG
     DKASYLPGGD LQFHGRMDDQ VKIRGFRIEL GEVEATLQAH LSVKEAVVLV REDHPGDKRL
     VAYVAGEGSV HEWREHLQTH LPNYMVPAHF VEMAFLPLTP NGKLDLKALP MPDEPSTENT
     VYPRTLMEEL IASVWSQVLE MENIGVQASF FELGGHSLLA TQVVSRLKEA LQIELLVREL
     FEHSTVEALA KRLDQLCKGD KKREIPPLIP MERGEAIPLS YAQQRLWFID QFQPNSALYN
     MPMVCRLTGN WVPEALETGW NRLIERHESL RTVFHEVDGQ PVQQIQPYAL RSLPKMDLTT
     LSPEEREREM EQWIKNEVEA PFDLVQGPLI RGQIVQIAEE EWILLCTMHH IISDGWSMEI
     LLQEWMAFYE DAVGGKPAEL APLPIQYADF AQWQREWLKE EVLDRQLAYW KEELSGELPV
     LMLPIDRPRP AVQTHSGSTH TVLLSRALRD KLNELSRQEG STLFMTLLAS YQSFLSRYTG
     QSDILVGSPI ANRNYREIEG LIGFFVNTLV YRADLSGAPT FQELLSQVRT KALKAYEYQD
     VPFEKIVEVI QSERSISHSP IFQTMFTLQN TKHELPELHG RSLEAMEIQD SNAKFDLSLS
     AIEKEEGLIL SFVFNTGLFD VVTIRRMAEH FEKWLNEIVE HPDKSLAKLT LLPEMERQLL
     EEWNDNAETY PRESVIHRLF EDQVDLTPDT VAVVDENQQL TYRELNEKAN QLAHYLQKCG
     VGTESLVGLC FQRSVEMIVG LMGIWKAGAA YVPLDPLYPE SRLRYILQDT GIQVLVTNEA
     LKEWIPEEVE AVCLDRDQAM ISRESTLSPI CEVAGENLAY VIYTSGSTGN PKGVLVQHHS
     VLNLSYGLQK EVFSHETPVN MRVGLNASIA FDVSIQQLQM LLYGSSLYII PDEVRSDPQQ
     FVSYIRENKL EMFDMTPSLL QLLIDGGLLE TNDGVHVPSK VLVGGEAIVP SLWEQLVEAD
     KIHFYNVYGP TECTVDATCY RIKKDGKRVT IGRPLPNVQA YVLDGNWLPV PVGVTGELYI
     GGAGLARGYL NRPELTSERF IPHPFKEGER LYRTGDLVRH LPDGNLDYLG RLDNQVKIRG
     FRIELGEIEA TLQEHLSVKE AVVMVREDQP GDKRLVAYVV GEGRKEEWRE YLKAQLPSHM
     VPAYFVGMEE LPLTLNGKID RKTLPVPDHQ GTKGGYVAPR NESEQILTMI WERVLGTKPI
     GIHENFFEIG GDSILSIQIV SRARQAGLQL TPKQMFEHQT ISELAQVVKE EQGVQAEQGV
     VTGELILTPI QQWFFAQDHP NPHHWNQSMF FRTKERLDIV LLEKAVRTLL IHHDALRLRY
     ERFPDGAWKQ RNEGIEEHST LTVISLEEVP QAEWHQVIQA EIDTAQASLH LHAGPLMRMV
     YFDEGEKRAG RLFWVIHHLA VDGVSWRILL EDLQTAYNQA SHAQMIQLPT KSTSFKAWSE
     KLHHYAEAGI VQGVRDYWEQ QSEQEVAMLP VDTTLEVPAN TGTEEITVVL DEKETRALLQ
     EISSTHRVQI NEVLLTALVQ ATAAWTGHTT LTVDLEGHGR EEIIEDVDLS RTVGWFTSIY
     PVHLNITGAN TPTAALKAVK EQVRQIPNKG VDYGILRYLN PAMRERFQSQ ITPSISFNYL
     GQFDQMFSDD AMFAPETGFT RLDHAPGSKR SHLIDVIGIV TDGKLHFTWV YNVGQFAEST
     IQSVAENMLH QLSGLIHSSG GESTLTVSDF AIANLIPADL NKVLCKMNRG KNYPIIDLYP
     LSPLQEGMIF HTLHDQGDEH SVPYMVQLSF LFKGKLDILT FEQAWKSTIQ RHEIFRSAFV
     WDEIENPLQV VYAHIPFKLN EVDWSALSAE EKEEKRKAFL ATDRKQAFLF DEAPLMRVTV
     IQEAEDEYRV VWTHHHILLD GWSLPLVFNE LLTVYQKRIK GEAVDLPKSP LYKKYIQWLK
     VQDLEQAEQF WREKLKGFTA PTLLGLESKE QEKGYTEKVT YLSEEQTQAL QNWAKRKRLT
     LNTVIQGAWA YLMSRYSGED DIVYGVTSSG RPTEIIDVEN IVGPFITTSP TRIKLLDDIK
     VMDWLQKIQE EEIERRQYEY ASLTDIQGWS EVPRGTPLFH SLYVFENYPV KEESSGNLEI
     GELEGVEQTH YPLGLTVVPE SQLLLKLKYD RSKFNGLTIE RMLGHLSQVL KQMIENVDQT
     LSELVYVTEI EKKQLLEEWN DNAAAYPRES VIHKLFEDQV DRTPDTVAVV DENQQLTYRE
     LNEKANQLAH YLHKCGVGTE SLVGLCFQRS VEMIVGLMGI WKAGAAYVPL DPAYPESHLR
     YILEDTGIQI LVTNEVSQGW IPEEVETVYL DRDQAMISQE NTLSPICKVT GENLAYVIYT
     SGSTGNPKGV LVQHHSVLNL SYGLQKEVFS HETPVNMRVG LNASIAFDSS VKQLQMLLYG
     SSLYIIPNEV RSDPQQFVSY IRENKLEMFD ITPSLLQLII DEGALETNDG VHVPSKVLVG
     GEAIMPSLWE QLVEADKVHF YNVYGPTECT VDATCYRIKK DSKRVTIGRP LPNVQAYVLD
     GNWLPVPVGV TGELYIGGAG LARGYLNRPE LTSERFIPHP FNDGERLYRT GDLVRYLADG
     HLDYLGRIDN QVKIRGFRIE LGEIEANLEC HPSVKEAVVL IREDQPGDQR LVAYVVGEGN
     MHEWREHLKR QVPNYMVPAH FIEVDAVPLT TNGKVDRKAL NSLTIQREST FSTPIIPRDE
     IEYQLITIWQ DLLQIEDVHV NDDFFDLGGH SLLVIKLISK VREKFGKEIK VSALIKNPTV
     EGIAYLIREN HGMAKSLSVL VPLQESEKRP FFCVHPFMGN VFCYIQLARL LKDHCSFYGL
     QNPLVEKEGM NGLTLSEVVQ LYIEEMKRAQ PVGPYRLGGW SLGGAIAYEI ATMLRNQGEE
     VEVLVLMDTK VPSEQDYKAE DEMLSYILEH FSHLELVEQE EELVHQQGML VDQLIAEGVL
     RPDADLTSLK QITDAHRKCL NLMAEHILTP YFGEVIYFSA EEGRELFTDW KPLLQGKVNK
     HSVPGPHEEI VFSPAVEKIA KSLVNEFEGS VTQISR
//
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