ID A0A140E4L9_9GAMM Unreviewed; 530 AA.
AC A0A140E4L9;
DT 06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT 06-JUL-2016, sequence version 1.
DT 24-JAN-2024, entry version 25.
DE RecName: Full=Aldehyde dehydrogenase {ECO:0000256|PIRNR:PIRNR036492};
GN ORFNames=JT25_002370 {ECO:0000313|EMBL:AMK75343.1};
OS Methylomonas denitrificans.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Methylococcales;
OC Methylococcaceae; Methylomonas.
OX NCBI_TaxID=1538553 {ECO:0000313|EMBL:AMK75343.1, ECO:0000313|Proteomes:UP000030512};
RN [1] {ECO:0000313|EMBL:AMK75343.1, ECO:0000313|Proteomes:UP000030512}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FJG1 {ECO:0000313|EMBL:AMK75343.1,
RC ECO:0000313|Proteomes:UP000030512};
RX PubMed=25580993; DOI=10.1111/1462-2920.12772;
RA Kits K.D., Klotz M.G., Stein L.Y.;
RT "Methane oxidation coupled to nitrate reduction under hypoxia by the
RT Gammaproteobacterium Methylomonas denitrificans, sp. nov. type strain
RT FJG1.";
RL Environ. Microbiol. 17:3219-3232(2015).
CC -!- SIMILARITY: Belongs to the aldehyde dehydrogenase family.
CC {ECO:0000256|ARBA:ARBA00009986, ECO:0000256|PIRNR:PIRNR036492,
CC ECO:0000256|RuleBase:RU003345}.
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DR EMBL; CP014476; AMK75343.1; -; Genomic_DNA.
DR RefSeq; WP_036272035.1; NZ_CP014476.1.
DR AlphaFoldDB; A0A140E4L9; -.
DR STRING; 1538553.JT25_002370; -.
DR KEGG; mdn:JT25_002370; -.
DR OrthoDB; 9812625at2; -.
DR Proteomes; UP000030512; Chromosome.
DR GO; GO:0016620; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR GO; GO:0006081; P:cellular aldehyde metabolic process; IEA:InterPro.
DR CDD; cd07099; ALDH_DDALDH; 1.
DR InterPro; IPR016161; Ald_DH/histidinol_DH.
DR InterPro; IPR016163; Ald_DH_C.
DR InterPro; IPR029510; Ald_DH_CS_GLU.
DR InterPro; IPR016162; Ald_DH_N.
DR InterPro; IPR015590; Aldehyde_DH_dom.
DR InterPro; IPR012394; Aldehyde_DH_NAD(P).
DR PANTHER; PTHR11699:SF211; ALDEHYDE DEHYDROGENASE FAMILY 16 MEMBER A1; 1.
DR PANTHER; PTHR11699; ALDEHYDE DEHYDROGENASE-RELATED; 1.
DR Pfam; PF00171; Aldedh; 1.
DR PIRSF; PIRSF036492; ALDH; 1.
DR SUPFAM; SSF53720; ALDH-like; 1.
DR PROSITE; PS00687; ALDEHYDE_DEHYDR_GLU; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000256|PIRNR:PIRNR036492};
KW Reference proteome {ECO:0000313|Proteomes:UP000030512}.
FT DOMAIN 3..450
FT /note="Aldehyde dehydrogenase"
FT /evidence="ECO:0000259|Pfam:PF00171"
FT ACT_SITE 234
FT /evidence="ECO:0000256|PIRSR:PIRSR036492-1,
FT ECO:0000256|PROSITE-ProRule:PRU10007"
FT ACT_SITE 268
FT /evidence="ECO:0000256|PIRSR:PIRSR036492-1"
SQ SEQUENCE 530 AA; 58362 MW; 62E4F1EE8ECDC516 CRC64;
MTTIQAVSPV DGRVLGDFPV SDQAVIQQQM LAARAAAHIW AKRPVAERAK ILAKLVPLLM
AELDSICELI SLTTGKVRTE ALLGEIYPVL DLARYYQKHA ANILSYRGIP TSPFAFPGAT
AGIERRPYGV VAVISPWNYP FQLSVGPMLT ALFAGNAAIL KPSELSLPIG QLIVDLFKQL
DLPEGLVQWL VGDGETGAQL IDASPDLVFF TGGLNSGKAV MQRAAQHPIP VMLELGGKDP
MLVFNDAQLP RAADAALYGA FCNSGQVCVS VERLYVQQDC HDEFLSLLQQ GVAQLQVGHD
PQGDLGAMTT ERQLAIVEAH FQDAIAQGAQ ASGPLEKQGN YLKPVVLWNV HHGMRVMREE
SFGPLLPVMA FADEAQAIHL ANDSEFGLNA SIWSRDITKA ERVAGQLEVG NWAINDVIKN
IGHPGLPFGG VKKSGFGRYH GAEGLRSFTY PVSGMTSRSH LPKEPNWFPY SEQRYQDFKG
YMDFVYGSGY LLQRIKRNWP ALQAFREYSA FDLTQRWQNL KLLLSWKRDY
//
