ID A0A143BTV5_9ACTN Unreviewed; 587 AA.
AC A0A143BTV5;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 24-JAN-2024, entry version 22.
DE SubName: Full=Beta-galactosidase {ECO:0000313|EMBL:AMW08687.1};
GN ORFNames=A4E84_03675 {ECO:0000313|EMBL:AMW08687.1};
OS Streptomyces qaidamensis.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces; Streptomyces aurantiacus group.
OX NCBI_TaxID=1783515 {ECO:0000313|EMBL:AMW08687.1, ECO:0000313|Proteomes:UP000076096};
RN [1] {ECO:0000313|EMBL:AMW08687.1, ECO:0000313|Proteomes:UP000076096}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=S10 {ECO:0000313|EMBL:AMW08687.1,
RC ECO:0000313|Proteomes:UP000076096};
RA Evans L.H., Alamgir A., Owens N., Weber N.D., Virtaneva K., Barbian K.,
RA Babar A., Rosenke K.;
RL Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 35 family.
CC {ECO:0000256|ARBA:ARBA00009809}.
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DR EMBL; CP015098; AMW08687.1; -; Genomic_DNA.
DR RefSeq; WP_062925155.1; NZ_CP015098.1.
DR AlphaFoldDB; A0A143BTV5; -.
DR STRING; 1783515.A4E84_03675; -.
DR KEGG; stsi:A4E84_03675; -.
DR Proteomes; UP000076096; Chromosome.
DR GO; GO:0004565; F:beta-galactosidase activity; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 2.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR InterPro; IPR026283; B-gal_1-like.
DR InterPro; IPR048912; BetaGal1-like_ABD1.
DR InterPro; IPR048913; BetaGal_gal-bd.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR031330; Gly_Hdrlase_35_cat.
DR InterPro; IPR019801; Glyco_hydro_35_CS.
DR InterPro; IPR001944; Glycoside_Hdrlase_35.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR PANTHER; PTHR23421:SF165; BETA-GALACTOSIDASE; 1.
DR PANTHER; PTHR23421; BETA-GALACTOSIDASE RELATED; 1.
DR Pfam; PF21317; BetaGal_ABD_1; 1.
DR Pfam; PF21467; BetaGal_gal-bd; 1.
DR Pfam; PF01301; Glyco_hydro_35; 1.
DR PIRSF; PIRSF006336; B-gal; 1.
DR PRINTS; PR00742; GLHYDRLASE35.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 2.
DR PROSITE; PS01182; GLYCOSYL_HYDROL_F35; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801}.
FT DOMAIN 11..324
FT /note="Glycoside hydrolase 35 catalytic"
FT /evidence="ECO:0000259|Pfam:PF01301"
FT DOMAIN 370..481
FT /note="Beta-galactosidase 1-like first all-beta"
FT /evidence="ECO:0000259|Pfam:PF21317"
FT DOMAIN 500..558
FT /note="Beta-galactosidase galactose-binding"
FT /evidence="ECO:0000259|Pfam:PF21467"
FT ACT_SITE 159
FT /note="Proton donor"
FT /evidence="ECO:0000256|PIRSR:PIRSR006336-1"
FT ACT_SITE 235
FT /note="Nucleophile"
FT /evidence="ECO:0000256|PIRSR:PIRSR006336-1"
SQ SEQUENCE 587 AA; 63422 MW; 8F77C60A23582D47 CRC64;
MPALTTTSDG FLLHGEPFRI ISGALHYFRV HPGLWSDRLR KARLMGLNTV ETYIPWNHHQ
PDPEAPLALD GFLDLPRFLR LAQDEGLRVL LRPGPFICAE WDGGGLPDWL TSDPDIRLRT
SDPRFTGAVD RYLDLLLPAL RPHLAAAGGP VIGVQVENEY GAYGDDSAYL KHLADAFRAR
GVEELLFTCD QADPEHLATG SVPGVLATGT FGSRVEQSLA RLREHQPEGP LFCAEFWIGW
FDHWGGPHHV RDAADAAADL DRLLSAGASV NIYMFHGGTN FGFANGANHK HAYTPTVTSY
DYDAALTECG DPGPKYHAFR EVIARHATVP DEPAPAPGPK LPPTPVDVDS RVALLPLAAS
LPGAVRTDAP VTMDELGQRT GYALYRTTFP ADGDGLLHFA RGVGDRAQVF VDGAPVGVLE
SERHDTSLPV RVPRPGATLE VLVENMGGVN YGPRIGAPKG LLGPVSFNGT DLTGWDCHPL
PPAPDALPFA PADDAPVTVP AFHRGTFEVG TPADAFLALP GWTKGQAWVN GFHLGRYWNR
GPQRTLYVPA PVLRPGSNEL VLLELHGSTA TRALLTDTPD LGPENTW
//
