ID A0A191V2B4_9ACTN Unreviewed; 537 AA.
AC A0A191V2B4;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Succinic semialdehyde dehydrogenase {ECO:0000313|EMBL:ANJ09072.1};
GN Name=gabD2 {ECO:0000313|EMBL:ANJ09072.1};
GN ORFNames=GCM10010220_37510 {ECO:0000313|EMBL:GGR81670.1},
GN Spa2297_20165 {ECO:0000313|EMBL:ANJ09072.1};
OS Streptomyces parvulus.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=146923 {ECO:0000313|EMBL:ANJ09072.1, ECO:0000313|Proteomes:UP000078468};
RN [1] {ECO:0000313|EMBL:ANJ09072.1, ECO:0000313|Proteomes:UP000078468}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=2297 {ECO:0000313|EMBL:ANJ09072.1,
RC ECO:0000313|Proteomes:UP000078468};
RA Nishizawa T., Miura T., Harada C., Guo Y., Narisawa K., Ohta H.,
RA Takahashi H., Shirai M.;
RT "Non-Contiguous Finished Genome Sequence of Streptomyces parvulus 2297
RT Integrated Site-Specifically with Actinophage R4.";
RL Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:GGR81670.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=JCM 4068 {ECO:0000313|EMBL:GGR81670.1};
RX PubMed=30832757;
RA Wu L., Ma J.;
RT "The Global Catalogue of Microorganisms (GCM) 10K type strain sequencing
RT project: providing services to taxonomists for standard genome sequencing
RT and annotation.";
RL Int. J. Syst. Evol. Microbiol. 69:895-898(2019).
RN [3] {ECO:0000313|EMBL:GGR81670.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=JCM 4068 {ECO:0000313|EMBL:GGR81670.1};
RA Sun Q., Ohkuma M.;
RL Submitted (DEC-2022) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the aldehyde dehydrogenase family.
CC {ECO:0000256|RuleBase:RU003345}.
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DR EMBL; CP015866; ANJ09072.1; -; Genomic_DNA.
DR EMBL; BMRX01000009; GGR81670.1; -; Genomic_DNA.
DR RefSeq; WP_064729402.1; NZ_CP015866.1.
DR AlphaFoldDB; A0A191V2B4; -.
DR KEGG; spav:Spa2297_20165; -.
DR Proteomes; UP000078468; Chromosome.
DR Proteomes; UP000645274; Unassembled WGS sequence.
DR GO; GO:0016620; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR CDD; cd07101; ALDH_SSADH2_GabD2; 1.
DR InterPro; IPR016161; Ald_DH/histidinol_DH.
DR InterPro; IPR016163; Ald_DH_C.
DR InterPro; IPR029510; Ald_DH_CS_GLU.
DR InterPro; IPR016162; Ald_DH_N.
DR InterPro; IPR015590; Aldehyde_DH_dom.
DR PANTHER; PTHR11699:SF211; ALDEHYDE DEHYDROGENASE FAMILY 16 MEMBER A1; 1.
DR PANTHER; PTHR11699; ALDEHYDE DEHYDROGENASE-RELATED; 1.
DR Pfam; PF00171; Aldedh; 1.
DR SUPFAM; SSF53720; ALDH-like; 1.
DR PROSITE; PS00687; ALDEHYDE_DEHYDR_GLU; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000256|RuleBase:RU003345}.
FT DOMAIN 46..501
FT /note="Aldehyde dehydrogenase"
FT /evidence="ECO:0000259|Pfam:PF00171"
FT REGION 1..26
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 40..64
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 274
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10007"
SQ SEQUENCE 537 AA; 57559 MW; 688A57CDCB1ABF4A CRC64;
MTDAQAPEIT GTNPLAPSPE GARTAADVVT PELVAQLTKG VAGSGRTANH SPFTGEKLAD
LPESTPEDVS RAFEQARAAQ AVWARTPLRR RAAVLLRFHD LVLERQAEVL DLIQLETGKA
RLHAHEEVQA VAVAARHYGR KAPAYLRPKR HTGAVPTLTK VTELRHPRGV VGQIVPWNYP
FELSVGDALP ALVAGNAVVM KPDTESCLTA LWARDLLIEA GLPADVLQAV IGVGPVIGPE
VVKHGDYVSF TGSTRTGREV ATVAADRLVG VSLELGGKNA MLVLDDADVE KAAAGAVRAC
FSSAGQLCVS IERLYVHESV ADAFLDRFAA RTRAMRLGSA LAYGADMGSL VSGHQLETVK
RHVEDAVAKG ARIVAGGVAR PDLGPYFYEP TILDGVTDEM TLCCEETFGP VVSVYRFSDV
DEVVDRANAT PYGLNSSVWT TNARRGREVA ARLRTGTVNI NEGYASAYGS VQSPMGGMKE
SGLGRRHGSE GILKYTESQT VAHQRLLPMA PSLGMDDEKY AAFMSRSLRL MKAFRFR
//
