ID A0A1B1M818_STRLN Unreviewed; 354 AA.
AC A0A1B1M818;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=Maltose operon transcriptional repressor {ECO:0000313|EMBL:ANS64785.1};
GN ORFNames=SLCG_5852 {ECO:0000313|EMBL:AXG57007.1}, SLINC_2561
GN {ECO:0000313|EMBL:ANS64785.1};
OS Streptomyces lincolnensis.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1915 {ECO:0000313|EMBL:ANS64785.1, ECO:0000313|Proteomes:UP000092598};
RN [1] {ECO:0000313|EMBL:ANS64785.1, ECO:0000313|Proteomes:UP000092598}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL 2936 {ECO:0000313|EMBL:ANS64785.1,
RC ECO:0000313|Proteomes:UP000092598};
RA Meng S.C.;
RT "Enhancement of antibiotic productionsby engineered nitrateutilization in
RT actinobacteria.";
RL Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:AXG57007.1, ECO:0000313|Proteomes:UP000253884}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LC-G {ECO:0000313|EMBL:AXG57007.1,
RC ECO:0000313|Proteomes:UP000253884};
RX PubMed=29574602; DOI=10.1007/s10295-018-2029-1;
RA Xu Y., Tan G., Ke M., Li J., Tang Y., Meng S., Niu J., Wang Y., Liu R.,
RA Wu H., Bai L., Zhang L., Zhang B.;
RT "Enhanced lincomycin production by co-overexpression of metK1 and metK2 in
RT Streptomyces lincolnensis.";
RL J. Ind. Microbiol. Biotechnol. 45:345-355(2018).
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DR EMBL; CP016438; ANS64785.1; -; Genomic_DNA.
DR EMBL; CP022744; AXG57007.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1B1M818; -.
DR STRING; 1915.SLINC_2561; -.
DR KEGG; sls:SLINC_2561; -.
DR PATRIC; fig|1915.4.peg.2833; -.
DR Proteomes; UP000092598; Chromosome.
DR Proteomes; UP000253884; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd01392; HTH_LacI; 1.
DR CDD; cd06292; PBP1_AglR_RafR-like; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR InterPro; IPR000843; HTH_LacI.
DR InterPro; IPR046335; LacI/GalR-like_sensor.
DR InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR30146:SF121; HTH-TYPE TRANSCRIPTIONAL REPRESSOR CYTR; 1.
DR PANTHER; PTHR30146; LACI-RELATED TRANSCRIPTIONAL REPRESSOR; 1.
DR Pfam; PF00356; LacI; 1.
DR Pfam; PF13377; Peripla_BP_3; 1.
DR PRINTS; PR00036; HTHLACI.
DR SMART; SM00354; HTH_LACI; 1.
DR SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS00356; HTH_LACI_1; 1.
DR PROSITE; PS50932; HTH_LACI_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000092598};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 13..64
FT /note="HTH lacI-type"
FT /evidence="ECO:0000259|PROSITE:PS50932"
SQ SEQUENCE 354 AA; 37410 MW; 9BDFB60D2DFCAFF1 CRC64;
MTIRPVQSGA VTTRLADIAA QAGVSEATVS RVLNGKPGVA ATTRQSVLAA LDVLGYERPV
RLRQRSEGLV GLITPELENP IFPALAQVIG QALTRQGYTP VLATQTPGGS TEDELTEMLV
DRGVAGIIFV SGLHADTSAD MQRYEQLRAQ GVPFVLVDGF SPKVQAPFIS PDDRAAMTLA
VTHLVSLGHT RIGLALGPKR FVPVQRKIEG FVRTMQDQLG LAAAAVESEF VQHSLYTLEG
GQAAATALMD RSCTAVVCAS DMMALGAIRA ARQRGLDVPR DVSVVGFDDS PLIAFTDPPL
TTVRKPVPAM GQAAVRTLLE EIGGTPAPHS EFVFMPELVV RGSTASAPGE RSRP
//
