ID A0A1C7D539_9SPHN Unreviewed; 537 AA.
AC A0A1C7D539;
DT 30-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 30-NOV-2016, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=site-specific DNA-methyltransferase (adenine-specific) {ECO:0000256|ARBA:ARBA00011900};
DE EC=2.1.1.72 {ECO:0000256|ARBA:ARBA00011900};
GN ORFNames=A6F65_00144 {ECO:0000313|EMBL:ANU06472.1};
OS Paraurantiacibacter namhicola.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC Erythrobacteraceae; Paraurantiacibacter.
OX NCBI_TaxID=645517 {ECO:0000313|EMBL:ANU06472.1, ECO:0000313|Proteomes:UP000092698};
RN [1] {ECO:0000313|EMBL:ANU06472.1, ECO:0000313|Proteomes:UP000092698}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JCM 16345 {ECO:0000313|EMBL:ANU06472.1,
RC ECO:0000313|Proteomes:UP000092698};
RA Cheng H., Wu Y.-H., Jian S.-L., Huo Y.-Y., Wang C.-S., Xu X.-W.;
RT "Complete genome sequence of Altererythrobacter namhicola JCM 16345T,
RT containing esterase-encoding genes.";
RL Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a 2'-deoxyadenosine in DNA + S-adenosyl-L-methionine = an
CC N(6)-methyl-2'-deoxyadenosine in DNA + H(+) + S-adenosyl-L-
CC homocysteine; Xref=Rhea:RHEA:15197, Rhea:RHEA-COMP:12418, Rhea:RHEA-
CC COMP:12419, ChEBI:CHEBI:15378, ChEBI:CHEBI:57856, ChEBI:CHEBI:59789,
CC ChEBI:CHEBI:90615, ChEBI:CHEBI:90616; EC=2.1.1.72;
CC Evidence={ECO:0000256|ARBA:ARBA00001279};
CC -!- SIMILARITY: Belongs to the N(4)/N(6)-methyltransferase family.
CC {ECO:0000256|ARBA:ARBA00006594}.
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DR EMBL; CP016545; ANU06472.1; -; Genomic_DNA.
DR RefSeq; WP_067784684.1; NZ_CP016545.1.
DR AlphaFoldDB; A0A1C7D539; -.
DR STRING; 645517.A6F65_00144; -.
DR REBASE; 155872; M2.Ana16345ORF143P.
DR KEGG; anh:A6F65_00144; -.
DR PATRIC; fig|645517.4.peg.145; -.
DR OrthoDB; 9806213at2; -.
DR Proteomes; UP000092698; Chromosome.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0009007; F:site-specific DNA-methyltransferase (adenine-specific) activity; IEA:UniProtKB-EC.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR002052; DNA_methylase_N6_adenine_CS.
DR InterPro; IPR011639; MethylTrfase_TaqI-like_dom.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR33841; DNA METHYLTRANSFERASE YEEA-RELATED; 1.
DR PANTHER; PTHR33841:SF5; TYPE II METHYLTRANSFERASE M.HINDII; 1.
DR Pfam; PF07669; Eco57I; 1.
DR PRINTS; PR00507; N12N6MTFRASE.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS00092; N6_MTASE; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW ECO:0000313|EMBL:ANU06472.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000092698};
KW Restriction system {ECO:0000256|ARBA:ARBA00022747};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 199..298
FT /note="Type II methyltransferase M.TaqI-like"
FT /evidence="ECO:0000259|Pfam:PF07669"
FT COILED 75..102
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 537 AA; 60202 MW; CF4D00E2289EA2F6 CRC64;
MSEQATFALK GRNPDVLSCI ANLSNDEVFT PPEFANRMLD TLEEAWAADN DGASIWADSS
VTFLDPCTKS GVFLREITKR LITGLEEEIP DLQERVDHIL TKQVFGIGIT QLTALLARRS
LYCSKHATGE HSVASTFDND NGNVWFERTE HSWVGGKCKY CGVAKETFER GDDMETHAYA
LIHTENAKAL AREIFGDSMQ FDVVIGNPPY QLNTGGYGTQ ARPIYHQFVE QAKALEPRYL
SMIIPSRWFS GGMGLDDFRQ SMLSDASVRS IDDFLAASDV FPGVGLKGGV CYFLWDRDNL
GACRVATHYQ GREPSIMTRP LLEEGADIFV RFNEGLSILK KVVAHETGSD GSLALPEEKR
FINLVSSIGA YGLESTFRGR DEKKDDDLKV YRNGGVGYIA RSEVGKEEHT FDKWKVFIGR
AAPGTGNKDT YPHKILSTPF LGEPGSISSW TYMYIGPFEK KSEAQSVLSY LSCRLTRLLI
LLHKPSADTT RKVYTFVPKQ DWSKMWSDAD LYEKYRLSDE EIGFIEAFVR PMDVEVD
//
