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Database: UniProt/TrEMBL
Entry: A0A1D9GNY8_9ALTE
LinkDB: A0A1D9GNY8_9ALTE
Original site: A0A1D9GNY8_9ALTE 
ID   A0A1D9GNY8_9ALTE        Unreviewed;       747 AA.
AC   A0A1D9GNY8;
DT   15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT   15-FEB-2017, sequence version 1.
DT   27-SEP-2017, entry version 6.
DE   SubName: Full=Isocitrate dehydrogenase (NADP(+)) {ECO:0000313|EMBL:AOY89348.1};
GN   ORFNames=BKP64_14870 {ECO:0000313|EMBL:AOY89348.1};
OS   Marinobacter salinus.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Alteromonadales;
OC   Alteromonadaceae; Marinobacter.
OX   NCBI_TaxID=1874317 {ECO:0000313|EMBL:AOY89348.1, ECO:0000313|Proteomes:UP000177445};
RN   [1] {ECO:0000313|EMBL:AOY89348.1, ECO:0000313|Proteomes:UP000177445}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Hb8 {ECO:0000313|EMBL:AOY89348.1,
RC   ECO:0000313|Proteomes:UP000177445};
RA   Park S.-J.;
RT   "Marinobacter salinus sp. nov., a moderately halophilic bacterium
RT   isolated from a tidal flat environment.";
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC         Evidence={ECO:0000256|PIRSR:PIRSR009407-3};
CC       Name=Mn(2+); Xref=ChEBI:CHEBI:29035;
CC         Evidence={ECO:0000256|PIRSR:PIRSR009407-3};
CC       Note=Binds 1 Mg(2+) or Mn(2+) ion per subunit.
CC       {ECO:0000256|PIRSR:PIRSR009407-3};
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DR   EMBL; CP017715; AOY89348.1; -; Genomic_DNA.
DR   RefSeq; WP_070971784.1; NZ_CP017715.1.
DR   KEGG; msq:BKP64_14870; -.
DR   KO; K00031; -.
DR   Proteomes; UP000177445; Chromosome.
DR   GO; GO:0004450; F:isocitrate dehydrogenase (NADP+) activity; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006099; P:tricarboxylic acid cycle; IEA:InterPro.
DR   InterPro; IPR004436; Isocitrate_DH_NADP_mono.
DR   Pfam; PF03971; IDH; 1.
DR   PIRSF; PIRSF009407; IDH_monmr; 1.
DR   TIGRFAMs; TIGR00178; monomer_idh; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000177445};
KW   Magnesium {ECO:0000256|PIRSR:PIRSR009407-3};
KW   Metal-binding {ECO:0000256|PIRSR:PIRSR009407-3};
KW   Reference proteome {ECO:0000313|Proteomes:UP000177445}.
FT   REGION      134    141       Substrate binding. {ECO:0000256|PIRSR:
FT                                PIRSR009407-2}.
FT   METAL       352    352       Magnesium or manganese.
FT                                {ECO:0000256|PIRSR:PIRSR009407-3}.
FT   METAL       550    550       Magnesium or manganese.
FT                                {ECO:0000256|PIRSR:PIRSR009407-3}.
FT   METAL       554    554       Magnesium or manganese.
FT                                {ECO:0000256|PIRSR:PIRSR009407-3}.
FT   BINDING     147    147       Substrate. {ECO:0000256|PIRSR:
FT                                PIRSR009407-2}.
FT   BINDING     549    549       Substrate. {ECO:0000256|PIRSR:
FT                                PIRSR009407-2}.
FT   SITE        257    257       Critical for catalysis.
FT                                {ECO:0000256|PIRSR:PIRSR009407-1}.
FT   SITE        422    422       Critical for catalysis.
FT                                {ECO:0000256|PIRSR:PIRSR009407-1}.
SQ   SEQUENCE   747 AA;  83441 MW;  DF9355C386DF7825 CRC64;
     MTSSKAKIVY TLTDEAPALA TRSLLPILET FAKPAGIEFE TSDISLAARI LANFPDYLEE
     DQRVPDALAQ LGDYTKDPDA NIIKLPNISA SIPQLRAAIK ELNDQGYKLP EYKENPETDE
     EKEIQSRYAK ALGSAVNPVL REGNSDRRAP AAVKAFARKY PHSMGEWSPA SRTHVAHMRG
     GDFYSSEQSV TLDKATTARI VFENKQGKQT VLKSELPLQE GEVLDGMFMS KKALVKFFED
     AIEDCEKTGV MFSLHVKATM MKISHPIVFG HAVKVFYKDL FDKYGDLFDE IGVNPNNGLS
     SVVEKIKQLP ESKQEQIQED LHACYEHRPE IAMVDSVKGI TNLHVPSDVI VDASMPAMIR
     NSGKMWARDN KLKDTKAVMP ESTYATIYQE VINFCKTHGA FDPTTMGTVP NVGLMAQKAE
     EYGSHDKTFE IKEDGVVRVI AEDGTVLTEH NVEQGDIWRA CQTKDLPIRD WVKLAVSRAR
     ATGMPAVFWL DDERAHDAQL IKKVETYLKD HDTDGLDIRI MSPVRAIRWT MERLIRGLDT
     ISVSGNVLRD YLTDLFPILE LGTSAKMLSI VPLLNGGGLY ETGAGGSAPK HVQQLIQENH
     LRWDSLGEFL ATAVSLDELG EKHGNDRARL LGQTLDKATE RLLENNQSPS RVTGELDNRG
     SHFHLARYWA EELSKQDSDK ELKEFFTKLS KQLEENKDKI LEEMTVVQGH PADIGGYYHP
     PAEKVCKVMQ PSETLNKILA DARASVK
//
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