GenomeNet

Database: UniProt/TrEMBL
Entry: A0A1I8MTB8_MUSDO
LinkDB: A0A1I8MTB8_MUSDO
Original site: A0A1I8MTB8_MUSDO 
ID   A0A1I8MTB8_MUSDO        Unreviewed;       597 AA.
AC   A0A1I8MTB8;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   27-SEP-2017, entry version 9.
DE   RecName: Full=Phosphotransferase {ECO:0000256|RuleBase:RU362007};
DE            EC=2.7.1.- {ECO:0000256|RuleBase:RU362007};
GN   Name=105261744 {ECO:0000313|VectorBase:MDOA008245-PA};
OS   Musca domestica (House fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
OC   Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha;
OC   Muscoidea; Muscidae; Musca.
OX   NCBI_TaxID=7370 {ECO:0000313|Proteomes:UP000095301, ECO:0000313|VectorBase:MDOA008245-PA};
RN   [1] {ECO:0000313|Proteomes:UP000095301, ECO:0000313|VectorBase:MDOA008245-PA}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Aabys {ECO:0000313|Proteomes:UP000095301,
RC   ECO:0000313|VectorBase:MDOA008245-PA};
RX   PubMed=25315136; DOI=10.1186/s13059-014-0466-3;
RA   Scott J.G., Warren W.C., Beukeboom L.W., Bopp D., Clark A.G.,
RA   Giers S.D., Hediger M., Jones A.K., Kasai S., Leichter C.A., Li M.,
RA   Meisel R.P., Minx P., Murphy T.D., Nelson D.R., Reid W.R.,
RA   Rinkevich F.D., Robertson H.M., Sackton T.B., Sattelle D.B.,
RA   Thibaud-Nissen F., Tomlinson C., van de Zande L., Walden K.K.,
RA   Wilson R.K., Liu N.;
RT   "Genome of the house fly, Musca domestica L., a global vector of
RT   diseases with adaptations to a septic environment.";
RL   Genome Biol. 15:RESEARCH0466.1-RESEARCH0466.16(2014).
RN   [2] {ECO:0000313|VectorBase:MDOA008245-PA}
RP   IDENTIFICATION.
RC   STRAIN=Aabys {ECO:0000313|VectorBase:MDOA008245-PA};
RG   VectorBase;
RL   Submitted (NOV-2016) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the hexokinase family.
CC       {ECO:0000256|RuleBase:RU362007, ECO:0000256|SAAS:SAAS00672880}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   RefSeq; XP_019891905.1; XM_020036346.1.
DR   GeneID; 105261744; -.
DR   KEGG; mde:105261744; -.
DR   VectorBase; MDOA008245-RA; MDOA008245-PA; MDOA008245.
DR   KO; K00844; -.
DR   Proteomes; UP000095301; Whole Genome Shotgun Assembly.
DR   GO; GO:0005623; C:cell; IEA:GOC.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0005536; F:glucose binding; IEA:InterPro.
DR   GO; GO:0004396; F:hexokinase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0001678; P:cellular glucose homeostasis; IEA:InterPro.
DR   GO; GO:0006096; P:glycolytic process; IEA:UniProtKB-KW.
DR   InterPro; IPR001312; Hexokinase.
DR   InterPro; IPR019807; Hexokinase_BS.
DR   InterPro; IPR022673; Hexokinase_C.
DR   InterPro; IPR022672; Hexokinase_N.
DR   PANTHER; PTHR19443; PTHR19443; 1.
DR   Pfam; PF00349; Hexokinase_1; 1.
DR   Pfam; PF03727; Hexokinase_2; 1.
DR   PROSITE; PS00378; HEXOKINASE_1; 1.
DR   PROSITE; PS51748; HEXOKINASE_2; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|RuleBase:RU362007,
KW   ECO:0000256|SAAS:SAAS00672869};
KW   Complete proteome {ECO:0000313|Proteomes:UP000095301};
KW   Glycolysis {ECO:0000256|RuleBase:RU362007,
KW   ECO:0000256|SAAS:SAAS00672870};
KW   Kinase {ECO:0000256|RuleBase:RU362007, ECO:0000256|SAAS:SAAS00672871};
KW   Nucleotide-binding {ECO:0000256|RuleBase:RU362007,
KW   ECO:0000256|SAAS:SAAS00672883};
KW   Reference proteome {ECO:0000313|Proteomes:UP000095301};
KW   Transferase {ECO:0000256|RuleBase:RU362007,
KW   ECO:0000256|SAAS:SAAS00672884}.
FT   DOMAIN      149    344       Hexokinase_1. {ECO:0000259|Pfam:PF00349}.
FT   DOMAIN      350    584       Hexokinase_2. {ECO:0000259|Pfam:PF03727}.
SQ   SEQUENCE   597 AA;  64632 MW;  9A5CBBBC338B150E CRC64;
     MDKELNVAMQ NASINECLKT ATTTDSSANG CCSKQNSAAT PTSPSTNTFG ARCPLPNGTV
     AAAAPKTNGC CCNCSATTTT KTSSPSSATI DRDETDRSSS ATAAAAAAAT FTLGGEGITG
     HKTTNPPPAA PTTTAPFANA SVAEKRKMVH ELCQQLILTD EQIDELTYRI LHEIKRGLAK
     DTHAKANVKC FVTYVQDLPN GNERGKFLAL DLGGTNFRVL LIHLKEDHDF QMESRIYAIP
     QHIMLGSGTQ LFDHIAECLS NFMVEHNVKS ERLPLGFTFS FPLTQLGLTK GLLVTWTKGF
     NCAGVVNEDV VQLLKDAIAR RGDVQIDVCA ILNDTTGTLM SCAWKNHNCK IGLIVGTGSN
     ACYVERVEEA EMFDGASNGK PHVLINTEWG AFGDNGALDF VRTEFDEEVD RHSINPGKQV
     FEKMISGMYM GELVRLAIVK MVNAGVLFKG QDSDVLMTRG QFFTKYVSEI EADEPGTYTN
     CRLVLEELGL TEATDDDCAN VRYICECVSR RAAHLVSSGI ACLINKMNEP HVTVGVDGSV
     YRFHPKFHTL MVEKISQLVK PGITFDLMLS EDGSGRGAAL VAAVACREDN LPKKKKE
//
DBGET integrated database retrieval system