ID   A0A1I8N1Y0_MUSDO        Unreviewed;      1099 AA.
AC   A0A1I8N1Y0;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   27-MAR-2024, entry version 42.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblMetazoa:MDOA010687-PD};
OS   Musca domestica (House fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Muscoidea;
OC   Muscidae; Musca.
OX   NCBI_TaxID=7370 {ECO:0000313|EnsemblMetazoa:MDOA010687-PD};
RN   [1] {ECO:0000313|EnsemblMetazoa:MDOA010687-PD}
RP   IDENTIFICATION.
RC   STRAIN=Aabys {ECO:0000313|EnsemblMetazoa:MDOA010687-PD};
RG   EnsemblMetazoa;
RL   Submitted (MAY-2020) to UniProtKB.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=H2O + N(6)-acetyl-L-lysyl-[histone] = acetate + L-lysyl-
CC         [histone]; Xref=Rhea:RHEA:58196, Rhea:RHEA-COMP:9845, Rhea:RHEA-
CC         COMP:11338, ChEBI:CHEBI:15377, ChEBI:CHEBI:29969, ChEBI:CHEBI:30089,
CC         ChEBI:CHEBI:61930; EC=3.5.1.98;
CC         Evidence={ECO:0000256|ARBA:ARBA00001028};
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DR   AlphaFoldDB; A0A1I8N1Y0; -.
DR   STRING; 7370.A0A1I8N1Y0; -.
DR   EnsemblMetazoa; MDOA010687-RD; MDOA010687-PD; MDOA010687.
DR   VEuPathDB; VectorBase:MDOA010687; -.
DR   eggNOG; KOG1343; Eukaryota.
DR   eggNOG; KOG1867; Eukaryota.
DR   Proteomes; UP000095301; Unassembled WGS sequence.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   CDD; cd10002; HDAC10_HDAC6-dom1; 1.
DR   Gene3D; 3.40.800.20; Histone deacetylase domain; 2.
DR   Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR   InterPro; IPR000286; His_deacetylse.
DR   InterPro; IPR023801; His_deacetylse_dom.
DR   InterPro; IPR037138; His_deacetylse_dom_sf.
DR   InterPro; IPR023696; Ureohydrolase_dom_sf.
DR   InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR   InterPro; IPR001607; Znf_UBP.
DR   PANTHER; PTHR10625:SF4; HISTONE DEACETYLASE 6, ISOFORM G; 1.
DR   PANTHER; PTHR10625; HISTONE DEACETYLASE HDAC1-RELATED; 1.
DR   Pfam; PF00850; Hist_deacetyl; 2.
DR   Pfam; PF02148; zf-UBP; 1.
DR   PRINTS; PR01270; HDASUPER.
DR   SMART; SM00290; ZnF_UBP; 1.
DR   SUPFAM; SSF52768; Arginase/deacetylase; 2.
DR   SUPFAM; SSF57850; RING/U-box; 1.
DR   PROSITE; PS50271; ZF_UBP; 1.
PE   4: Predicted;
SQ   SEQUENCE   1099 AA;  123771 MW;  FB86EC82C969C0D7 CRC64;
     MSSPIVTRRG AQKAKIQTRA MVKSSVENRK PNAALLEAKR KAKLLKMQQP TQLDGTVKDI
     FQNAVNAKYM KQRPTGLVYD ESMSQHRCLW DDKHPECPER FIRVLDRCRE LNLVERCQLI
     SSRRATKDEI MLLHSEEHYK LLEKTSGVHD DEKMEDFSSH YDSVYIHPTT FDLSLLAAGS
     TIDLVENVVS GTIQNGMAII RPPGHHAMKA EFNGYCFFNN VAIATQYALD ILKVNKILII
     DWDVHHGQGT QRFFYHDPRV LYFSIHRFEH GTFWPNLKES DFDAIGYGPG LGYNFNLPLN
     KTGMTNGDYL AIFQQILIPV ACEFQPELII VSAGYDAALG CPEGEMEVTP AFYSHLINPL
     LKLANSRLAV VLEGGYCLES LAEGAALTLR ALLGEPCPAL VEKLEPPCPS IQESIFNCIY
     AHRPYWKCLQ AQGTYTMEDI NNVNPQNNLH KVSRLFVGGS PLPERFPTRD TAPKIPLDVI
     ERNAQRLKRL KAETKLFSPK VRVCYVYDEL MLQHANTYEE GHPEQPARIQ KIYEMHQDYK
     LLERMQKLPS RSATTDEVCL AHTRSHLNSI RRIGEKDELQ NMGAKFNSVY FHPKTFECAT
     LAAGSVLQVV DKVVKGEARS GVCIVRPPGH HAESDVPHGF CIFNNVAIAA QYAIRDHGLK
     RVLIVDWDVH HGNGTQHIFE SNPNVLYISI HRYDNASFFP KSKDGDFDCV GKGAGIGFNV
     NIPWNKKGMG DLEYIMAFQH IIMPIAYEFD PQLVLVSAGF DAAIGDPLGG CKVTPEAYGL
     FTHWLSALAN GRIIVCLEGG YNVNSISYAM TMCTKSLLGD PIPPVQLNGS YIRPPTAAYL
     SCIETLQNCI SVQERYWKSL AFGKRLPQVS GENNNEDFLS ATLQNLDITR DDVQGAAGGS
     GDAQQDISLE ASGSKPKVKV KTLTEFLTEH MQAFENNEMF AVVPLKHCPH LSQLHPEDAP
     KSINTNQPCN ECSSVAENWM CLSCHKVLCG RYVMEHMMFH NIETSHPMAL SFSDLSVWCY
     PCESYIDNRQ LHVYKNLAHL NKFGEEMQWA YEEDEQPDKS KRKDDDSDDD DDDDDSSSCS
     RPFGSQQNYY IQLNVDSNN
//