ID A0A1P8NHF0_9MICO Unreviewed; 483 AA.
AC A0A1P8NHF0;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 24-JAN-2024, entry version 31.
DE RecName: Full=Aldehyde dehydrogenase {ECO:0000256|PIRNR:PIRNR036492};
GN ORFNames=BH708_14650 {ECO:0000313|EMBL:APX33746.1};
OS Brachybacterium sp. P6-10-X1.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Dermabacteraceae;
OC Brachybacterium.
OX NCBI_TaxID=1903186 {ECO:0000313|EMBL:APX33746.1, ECO:0000313|Proteomes:UP000185991};
RN [1] {ECO:0000313|EMBL:APX33746.1, ECO:0000313|Proteomes:UP000185991}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=P6-10-X1 {ECO:0000313|EMBL:APX33746.1,
RC ECO:0000313|Proteomes:UP000185991};
RA Zhao B., Liao L., Chen B.;
RT "Complete genome of Brachybacterium sp. P6-10-X1.";
RL Submitted (SEP-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the aldehyde dehydrogenase family.
CC {ECO:0000256|ARBA:ARBA00009986, ECO:0000256|PIRNR:PIRNR036492,
CC ECO:0000256|RuleBase:RU003345}.
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DR EMBL; CP017297; APX33746.1; -; Genomic_DNA.
DR RefSeq; WP_076809828.1; NZ_CP017297.1.
DR AlphaFoldDB; A0A1P8NHF0; -.
DR STRING; 1903186.BH708_14650; -.
DR KEGG; brx:BH708_14650; -.
DR OrthoDB; 6882680at2; -.
DR Proteomes; UP000185991; Chromosome.
DR GO; GO:0016620; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR GO; GO:0006081; P:cellular aldehyde metabolic process; IEA:InterPro.
DR CDD; cd07087; ALDH_F3-13-14_CALDH-like; 1.
DR InterPro; IPR016161; Ald_DH/histidinol_DH.
DR InterPro; IPR016163; Ald_DH_C.
DR InterPro; IPR016160; Ald_DH_CS_CYS.
DR InterPro; IPR029510; Ald_DH_CS_GLU.
DR InterPro; IPR016162; Ald_DH_N.
DR InterPro; IPR015590; Aldehyde_DH_dom.
DR InterPro; IPR012394; Aldehyde_DH_NAD(P).
DR PANTHER; PTHR43570; ALDEHYDE DEHYDROGENASE; 1.
DR PANTHER; PTHR43570:SF16; ALDEHYDE DEHYDROGENASE TYPE III, ISOFORM Q; 1.
DR Pfam; PF00171; Aldedh; 1.
DR PIRSF; PIRSF036492; ALDH; 1.
DR SUPFAM; SSF53720; ALDH-like; 1.
DR PROSITE; PS00070; ALDEHYDE_DEHYDR_CYS; 1.
DR PROSITE; PS00687; ALDEHYDE_DEHYDR_GLU; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000256|PIRNR:PIRNR036492}.
FT DOMAIN 30..451
FT /note="Aldehyde dehydrogenase"
FT /evidence="ECO:0000259|Pfam:PF00171"
FT REGION 1..24
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 233
FT /evidence="ECO:0000256|PIRSR:PIRSR036492-1,
FT ECO:0000256|PROSITE-ProRule:PRU10007"
FT ACT_SITE 267
FT /evidence="ECO:0000256|PIRSR:PIRSR036492-1"
SQ SEQUENCE 483 AA; 52206 MW; 6621B382FA3E21E7 CRC64;
MSTDATSPTP PAPEPGDGPD PAVRPAITAD VAALRASFDA GTTREVSARL AQLEALRTGL
RHERRRLTRA LAQDLGKNGT EAAITEIGVV TQEIAHVRRH LRSWLRPSSL SLGAVLAPSS
GEVRREPLGL TLIIAPWNYP LNLTLTPLVS AIAGGNTVIV KPSEVAPATS AALAHLLRTW
LDPAWVRVVE GAVEETTVLL QQRFDLIFYT GNAAVGRIVA RAAAEHLTPT VLELGGKSPV
FVDDGVDLAV AARRIVWGKF TNTGQTCVAP DYLMATPDTL EKLVPHLRRA TRAMYGRDPR
RSRDYGRMVD LKHFDRVRGL IDDERAVLGG TGEADRAERY LPPTIMADVD WDDPVMAEEI
FGPVLPLLAV GGPDEAIARI REREKPLTAY VFTGKTAIEE RFATETSSGS LAVGMTLAHV
GVPTLPFGGV GESGNGAYHG RAGVQTFTHA KPIARKPLTP DTLRIVYPPY TRAKRALLKR
LFR
//
