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Database: UniProt/TrEMBL
Entry: A0A1P8Y0Q7_9ACTN
LinkDB: A0A1P8Y0Q7_9ACTN
Original site: A0A1P8Y0Q7_9ACTN 
ID   A0A1P8Y0Q7_9ACTN        Unreviewed;      1281 AA.
AC   A0A1P8Y0Q7;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   30-AUG-2017, entry version 4.
DE   SubName: Full=Alpha-ketoglutarate decarboxylase {ECO:0000313|EMBL:AQA14026.1};
GN   Name=kgd {ECO:0000313|EMBL:AQA14026.1};
GN   ORFNames=BV401_30070 {ECO:0000313|EMBL:AQA14026.1};
OS   Streptomyces autolyticus.
OC   Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae;
OC   Streptomyces.
OX   NCBI_TaxID=75293 {ECO:0000313|EMBL:AQA14026.1, ECO:0000313|Proteomes:UP000187851};
RN   [1] {ECO:0000313|Proteomes:UP000187851}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CGMCC0516 {ECO:0000313|Proteomes:UP000187851};
RA   Yin M., Jiang M., Lu T.;
RT   "Streptomyces autolyticus CGMCC0516 complete genome sequence.";
RL   Submitted (JAN-2017) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; CP019458; AQA14026.1; -; Genomic_DNA.
DR   Proteomes; UP000187851; Chromosome.
DR   GO; GO:0004591; F:oxoglutarate dehydrogenase (succinyl-transferring) activity; IEA:InterPro.
DR   GO; GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
DR   GO; GO:0016746; F:transferase activity, transferring acyl groups; IEA:InterPro.
DR   GO; GO:0006099; P:tricarboxylic acid cycle; IEA:InterPro.
DR   InterPro; IPR001078; 2-oxoacid_DH_actylTfrase.
DR   InterPro; IPR032106; 2-oxogl_dehyd_N.
DR   InterPro; IPR011603; 2oxoglutarate_DH_E1.
DR   InterPro; IPR001017; DH_E1.
DR   InterPro; IPR031717; KGD_C.
DR   InterPro; IPR029061; THDP-binding.
DR   InterPro; IPR005475; Transketolase-like_Pyr-bd.
DR   PANTHER; PTHR23152; PTHR23152; 1.
DR   Pfam; PF00198; 2-oxoacid_dh; 1.
DR   Pfam; PF16078; 2-oxogl_dehyd_N; 1.
DR   Pfam; PF00676; E1_dh; 1.
DR   Pfam; PF16870; OxoGdeHyase_C; 1.
DR   Pfam; PF02779; Transket_pyr; 1.
DR   SMART; SM00861; Transket_pyr; 1.
DR   SUPFAM; SSF52518; SSF52518; 2.
DR   TIGRFAMs; TIGR00239; 2oxo_dh_E1; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000187851}.
FT   DOMAIN      933   1126       Transket_pyr. {ECO:0000259|SMART:
FT                                SM00861}.
SQ   SEQUENCE   1281 AA;  140009 MW;  C143F8E0C2E3B4D2 CRC64;
     MSPQSPNTSS VSTEEQDGQG SNPAAAFGPN EWLVDEIYQQ YLQDPNSVDR AWWDFFADYK
     PGQDTGSAVA APPQAVAASA APAAPAKPAA AQPAEAKPAV PAAKPAAAAP AAPKPAAAQP
     AAPAAKAAPA APAAPAKPAP VKPTPAEPTV SKKEPAAPAA GPEFVTLRGP SAAVAKNMNA
     SLELPTATSV RAVPVKLLFD NRIVINNHLK RARGGKVSFT HLIGYAMVQA LKAMPSMNHS
     FAEKDGKPTL VKPEHINLGL AIDLVKPNGD RQLVVAAIKK AETLNFFEFW QAYEDIVRRA
     RAGKLTMDDF TGVTASLTNP GGIGTVHSVP RLMPGQGLIV GVGAMEYPAE FQGTSQDTLN
     KLGISKVMTL TSTYDHRVIQ GAASGEFLRI MSQLLLGEND FFDEIFKALR IPYEPVRWLK
     DIDVSHDDDV TKAARVFDLI HSYRVRGHVM ADTDPLEYRQ RKHPDLDIIE HGLTLWDLER
     EFAVGGFAGK TMMKLRDILG VLRDSYCRTT GIEFMHIQDP KQRKWIQDRV ERSHDKPERE
     EQLRILRRLN AAEAFETFLQ TKYVGQKRFS LEGGESVIPL LDAVLDAAAE SRLDEVVVGM
     AHRGRLNVLA NIVGKSYAQI FREFEGNLDP KSMHGSGDVK YHLGADGTFT GLDGEQIKVS
     LTANPSHLEA VDPVLEGVVR AKQDIIGKAG TDFTVLPVAL HGDAAFAGQG VVAETLNMSQ
     LRGYRTGGTV HIVINNQVGF TAAPAASRSS MYATDVARMI EAPIFHVNGD DPEAVVRVAR
     LAFEFRQAFN KDVVIDLICY RRRGHNETDN PGFTQPLMYD LIDKKRSVRK LYTESLIGRG
     DITLEEAEQA LQDFQGQLEK VFTEVRDAVS APAPAHVPEP QPEFPVTVQT AVSQEVVKRI
     AESQVNIPDR ITVHPRLYPQ LQRRAAMIED DSIDWGMGET LAIGSLLMEG TPVRLAGQDS
     RRGTFGQRHA VLVDRETGDD YTPLLYLTED QGRYNVYDSL LSEYAAMGFE YGYSLARPDA
     LVMWEAQFGD FVNGAQTIVD EFISSAEQKW GQTSGVTLLL PHGYEGQGPD HSSARIERFL
     QLCAQNNMTV AAPTLPSNYF HLLRWQVHNP HHKPLVVFTP KSMLRLKAAA SSTEEFLSGS
     FRPVIGDETA DPAAVRKVVF CSGKVYYDLA AERDKRGAHD TAIIRLERLY PLPGAELQAE
     IAKYSGVQKF VWAQEEPANQ GAWPFVALNL IDHLELSVGA DVPAAERLVR VSRPHSSSPA
     VGSNKRHQSE QGALVSEVFE I
//
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