ID A0A1S2YVG4_CICAR Unreviewed; 531 AA.
AC A0A1S2YVG4;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=alanine transaminase {ECO:0000256|ARBA:ARBA00026106};
DE EC=2.6.1.2 {ECO:0000256|ARBA:ARBA00026106};
GN Name=LOC101489034 {ECO:0000313|RefSeq:XP_004510570.1};
OS Cicer arietinum (Chickpea) (Garbanzo).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC NPAAA clade; Hologalegina; IRL clade; Cicereae; Cicer.
OX NCBI_TaxID=3827 {ECO:0000313|Proteomes:UP000087171, ECO:0000313|RefSeq:XP_004510570.1};
RN [1] {ECO:0000313|RefSeq:XP_004510570.1}
RP IDENTIFICATION.
RC TISSUE=Etiolated seedlings {ECO:0000313|RefSeq:XP_004510570.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|ARBA:ARBA00001933};
CC -!- PATHWAY: Amino-acid degradation; L-alanine degradation via transaminase
CC pathway; pyruvate from L-alanine: step 1/1.
CC {ECO:0000256|ARBA:ARBA00025708}.
CC -!- PATHWAY: Photosynthesis; C4 acid pathway.
CC {ECO:0000256|ARBA:ARBA00025709}.
CC -!- SUBUNIT: Homodimer. {ECO:0000256|ARBA:ARBA00011738}.
CC -!- SIMILARITY: Belongs to the class-I pyridoxal-phosphate-dependent
CC aminotransferase family. Alanine aminotransferase subfamily.
CC {ECO:0000256|ARBA:ARBA00025785}.
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DR RefSeq; XP_004510570.1; XM_004510513.3.
DR AlphaFoldDB; A0A1S2YVG4; -.
DR STRING; 3827.A0A1S2YVG4; -.
DR PaxDb; 3827-XP_004510570-1; -.
DR GeneID; 101489034; -.
DR KEGG; cam:101489034; -.
DR eggNOG; KOG0258; Eukaryota.
DR OrthoDB; 5472891at2759; -.
DR UniPathway; UPA00322; -.
DR UniPathway; UPA00528; UER00586.
DR Proteomes; UP000087171; Chromosome Ca7.
DR GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR GO; GO:0008483; F:transaminase activity; IEA:UniProtKB-KW.
DR GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR GO; GO:0042853; P:L-alanine catabolic process; IEA:UniProtKB-UniPathway.
DR CDD; cd00609; AAT_like; 1.
DR Gene3D; 1.10.287.1970; -; 1.
DR Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR InterPro; IPR045088; ALAT1/2-like.
DR InterPro; IPR004839; Aminotransferase_I/II.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR PANTHER; PTHR11751; ALANINE AMINOTRANSFERASE; 1.
DR PANTHER; PTHR11751:SF29; ALANINE TRANSAMINASE; 1.
DR Pfam; PF00155; Aminotran_1_2; 1.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
PE 3: Inferred from homology;
KW Aminotransferase {ECO:0000313|RefSeq:XP_004510570.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000087171};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 155..509
FT /note="Aminotransferase class I/classII"
FT /evidence="ECO:0000259|Pfam:PF00155"
SQ SEQUENCE 531 AA; 58655 MW; 58544D3CE7DD7544 CRC64;
MRKSAADRFK HLFNRSLVFV RHQNQQHNSS SPLHYRLLSS AHFSSMASDS PFPVTAQNIN
PQVLQCQYAV RGEIVTLAQN LQKDLQANPG SHSFDEIIYC NIGNPQSLGQ QPITFFREVL
ALCDYPALLD KSETQGLFSA DSIERAWQIV EQIPGRATGA YSHSQGIQGL RDTIAAGIQE
RDGFPANAND IFLTDGASPA VHMMMQLLIR SENDGILCPI PQYPLYSASI TLHGGHLVPY
YLDEATGWGL EVSEVKKQLE DAKSKGISVR ALVVINPGNP TGQVLAEENQ RDIVEFCKQE
GLVLLADEVY QENVYVPEKK FHSFKKVSRS MGYGDDDISL VSFQSVSKGY HGECGKRGGY
MEVTGFSPDV REQIYKVSSV NLCSNITGQI LASLVMSPPK VGDESYESFM AEKGSILSSL
ATRAKSLEEA LNKLEGVTCN KAEGAMYLFP QIRLPKKAIE AAEAENTAPD AFYCKRLLNA
TGVVVVPGSG FGQVPGTWHF RCTILPQEDK IPAIVTRLTE FHEKFMDEFR D
//
