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Database: UniProt/TrEMBL
Entry: A0A1S3IQM4_LINUN
LinkDB: A0A1S3IQM4_LINUN
Original site: A0A1S3IQM4_LINUN 
ID   A0A1S3IQM4_LINUN        Unreviewed;       906 AA.
AC   A0A1S3IQM4;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   22-NOV-2017, entry version 5.
DE   RecName: Full=DNA ligase {ECO:0000256|RuleBase:RU000617};
DE            EC=6.5.1.1 {ECO:0000256|RuleBase:RU000617};
GN   Name=LOC106165996 {ECO:0000313|RefSeq:XP_013399844.1};
OS   Lingula unguis.
OC   Eukaryota; Metazoa; Lophotrochozoa; Brachiopoda; Linguliformea;
OC   Lingulata; Lingulida; Linguloidea; Lingulidae; Lingula.
OX   NCBI_TaxID=7574 {ECO:0000313|Proteomes:UP000085678, ECO:0000313|RefSeq:XP_013399844.1};
RN   [1] {ECO:0000313|RefSeq:XP_013399844.1}
RP   IDENTIFICATION.
RC   TISSUE=Gonads {ECO:0000313|RefSeq:XP_013399844.1};
RG   RefSeq;
RL   Submitted (FEB-2017) to UniProtKB.
CC   -!- CATALYTIC ACTIVITY: ATP + (deoxyribonucleotide)(n)-3'-hydroxyl +
CC       5'-phospho-(deoxyribonucleotide)(m) = (deoxyribonucleotide)(n+m) +
CC       AMP + diphosphate. {ECO:0000256|RuleBase:RU000617}.
CC   -!- SIMILARITY: Belongs to the ATP-dependent DNA ligase family.
CC       {ECO:0000256|RuleBase:RU004196}.
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DR   RefSeq; XP_013399844.1; XM_013544390.1.
DR   GeneID; 106165996; -.
DR   KEGG; lak:106165996; -.
DR   KO; K10777; -.
DR   Proteomes; UP000085678; Genome assembly.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003910; F:DNA ligase (ATP) activity; IEA:UniProtKB-EC.
DR   GO; GO:0071897; P:DNA biosynthetic process; IEA:InterPro.
DR   GO; GO:0051103; P:DNA ligation involved in DNA repair; IEA:InterPro.
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR   CDD; cd00027; BRCT; 2.
DR   Gene3D; 1.10.3260.10; -; 1.
DR   Gene3D; 3.40.50.10190; -; 2.
DR   InterPro; IPR001357; BRCT_dom.
DR   InterPro; IPR036420; BRCT_dom_sf.
DR   InterPro; IPR000977; DNA_ligase_ATP-dep.
DR   InterPro; IPR012309; DNA_ligase_ATP-dep_C.
DR   InterPro; IPR012310; DNA_ligase_ATP-dep_cent.
DR   InterPro; IPR016059; DNA_ligase_ATP-dep_CS.
DR   InterPro; IPR012308; DNA_ligase_ATP-dep_N.
DR   InterPro; IPR021536; DNA_ligase_IV_dom.
DR   InterPro; IPR036599; DNA_ligase_N_sf.
DR   InterPro; IPR029710; LIG4.
DR   InterPro; IPR012340; NA-bd_OB-fold.
DR   PANTHER; PTHR10459:SF7; PTHR10459:SF7; 1.
DR   Pfam; PF16589; BRCT_2; 1.
DR   Pfam; PF04679; DNA_ligase_A_C; 1.
DR   Pfam; PF01068; DNA_ligase_A_M; 1.
DR   Pfam; PF04675; DNA_ligase_A_N; 1.
DR   Pfam; PF11411; DNA_ligase_IV; 1.
DR   SMART; SM00292; BRCT; 2.
DR   SUPFAM; SSF117018; SSF117018; 1.
DR   SUPFAM; SSF50249; SSF50249; 1.
DR   SUPFAM; SSF52113; SSF52113; 2.
DR   TIGRFAMs; TIGR00574; dnl1; 1.
DR   PROSITE; PS50172; BRCT; 2.
DR   PROSITE; PS00697; DNA_LIGASE_A1; 1.
DR   PROSITE; PS00333; DNA_LIGASE_A2; 1.
DR   PROSITE; PS50160; DNA_LIGASE_A3; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|RuleBase:RU000617};
KW   Complete proteome {ECO:0000313|Proteomes:UP000085678};
KW   DNA damage {ECO:0000256|RuleBase:RU000617};
KW   DNA recombination {ECO:0000256|RuleBase:RU000617};
KW   DNA repair {ECO:0000256|RuleBase:RU000617};
KW   DNA replication {ECO:0000256|RuleBase:RU000617};
KW   Ligase {ECO:0000256|RuleBase:RU000617,
KW   ECO:0000313|RefSeq:XP_013399844.1};
KW   Nucleotide-binding {ECO:0000256|RuleBase:RU000617};
KW   Reference proteome {ECO:0000313|Proteomes:UP000085678}.
FT   DOMAIN      348    482       DNA_LIGASE_A3. {ECO:0000259|PROSITE:
FT                                PS50160}.
FT   DOMAIN      648    731       BRCT. {ECO:0000259|PROSITE:PS50172}.
FT   DOMAIN      838    905       BRCT. {ECO:0000259|PROSITE:PS50172}.
SQ   SEQUENCE   906 AA;  103292 MW;  1CBFD77F8488B6E7 CRC64;
     MTTVASKVPF SELAGLLEKI SKKQGADKKL LLQEFINRWR DFHGKLHADD ANTTDSFYSA
     LRLLLPHLER ERAAYGIKEN TLAKLYIEVL CLGKDSPAAD KLIKYRAPKN AKGDAGDFAT
     VAYFVLKPRC PEKGSLTIEE VNQCLDGIAT NQTTGKKDLV RKNILHLLRN LSALEQKWLI
     RMIMKELKCG LSQQAILNVF HPDANEYFNV TTSLEKVCAN LKDPSTRMHE IEISVGAPFH
     PMLGELAVPK QLDKIMEGKM FYIEIKFDGE RMQLHKKEDE YMYFSRNGHN YSRTFGENPY
     DGNLTPYIAN CFKPGVKNCI LDGEMVGIHP ETKIIRTKGE NFDIKSDTNL DGYQPCLCVF
     DILLLNDRVL SNLPLRERKE ILKDVFNPVE CRMFIAESKE ATTSKECLQA LNDAIDKREE
     GIMVKNPDSV YKPSVRKGGW YKIKPEYMRG LGDDLDVLVV GGYFGVGARG GLVSHFLCAV
     AEPFEPGEKP SKFRSFCRVG SGYSRKELFE FNRRMQDKWI PYSDRKGPPS WLILGREKPS
     LLVEPSDSTI LQIKASEITS DSDKFGTGCT LRFPRVEKIR SDKPWHECLT FTELKELQEQ
     FAGKLAGRHA DEDHEDEPIK KKKKVVVRQE KPLVAPQFRA TDTSQVKKVS ELFEDKEFCV
     VNGSSKHSKA SLEKKIVEYG GTAVQHPGPE TFCVLCDKVQ MKVKNIISTN KHDVVKLDWL
     VRCTEARRLL PWVPSDMLHA RPETEALFKQ NYDDYGDSYT EDTTIDQLMV VFKKVQEEGK
     LKPVSTDFIA EIENKYFVEG STYGLFRLCR VYLDDNTVIG DKSTHIKDCS LELTSLELRM
     YGATLCEMLN EDVTHVVLCD RDLGRIDKFR SLNRSRWQKF HIVTQDWVSD CIDNGKILGE
     RGYEPA
//
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